Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Khyati Chandratre"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract The three-dimensional genome organization influences diverse nuclear processes. Here we present Chromatin Interaction Predictor (ChIPr), a suite of regression models based on deep neural networks, random forest, and gradient boosting to pred
Externí odkaz:
https://doaj.org/article/03fc82b49e5643149ec845f72b125c33
Autor:
Hemant Gupta, Khyati Chandratre, Siddharth Sinha, Teng Huang, Xiaobing Wu, Jian Cui, Michael Q. Zhang, San Ming Wang
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Core promoter controls transcription initiation. However, little is known for core promoter diversity in the human genome and its relationship with diseases. We hypothesized that as a functional important component in the genome,
Externí odkaz:
https://doaj.org/article/5940bad1ba09478eb7fbaee648bf6405
The three-dimensional (3D) genome organization influences diverse nuclear processes. Chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) and Hi-C are powerful methods to study the 3D genome organization. However, ChIA-PET and Hi-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::120ee2ccc77d70e380827e0ff887f1cd
https://doi.org/10.1101/2022.11.23.517572
https://doi.org/10.1101/2022.11.23.517572
Autor:
Ce Rong, Guoping Zhao, Maoni Guo, San Ming Wang, Ning Wang, Hui Dong, Xiaoqing Tian, Jing Zhang, Yue Qin, Khyati Chandratre
Publikováno v:
Journal of Medical Genetics. 58:565-569
BackgroundPathogenic variation inBRCA1andBRCA2(BRCA) is one of the most frequent genetic predispositions for hereditary breast cancer. The identification of the variant carriers plays an important role in prevention and treatment of cancer. Despite a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a9321c929cdbd724eeab00e21b28807
https://doi.org/10.1136/jmedgenet-2020-106970
https://doi.org/10.1136/jmedgenet-2020-106970
Autor:
Hui Dong, San Ming Wang, Li Zhang, Xiaoyu Wang, Shanmuga Priya Bhaskaran, Wen-Ming Cao, Xiaobing Wu, Teng Huang, Tianhui Chen, Henry T. Lynch, Khyati Chandratre, Zixin Qin
Publikováno v:
European Journal of Cancer. 125:12-21
Purpose DNA mismatch repair (MMR) genes play important roles in maintaining genome stability. Mutations in MMR genes disrupt their mismatch repair function, cause genome instability and lead to increased risk of cancer in the mutation carriers as rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb84753a9404eae554b48f5395ea348
https://doi.org/10.1016/j.ejca.2019.11.004
https://doi.org/10.1016/j.ejca.2019.11.004
Autor:
Boya Lu, Jian Cui, Yeong C. Kim, Luhan Jiang, Zixin Qin, Siddharth Sinha, Teng Huang, Xiaobing Wu, Khyati Chandratre, Li Zhang, Xiaoyu Wang, Shanmuga Priya Bhaskaran, Hemant Gupta, San Ming Wang
Publikováno v:
International Journal of Cancer
BRCA1 and BRCA2 play essential roles in maintaining the genome stability. Pathogenic germline mutations in these two genes disrupt their function, lead to genome instability and increase the risk of developing breast and ovarian cancers. BRCA mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450276311aa5353cacabf215abf8f5bd
http://europepmc.org/articles/PMC6617753
http://europepmc.org/articles/PMC6617753
Autor:
Khyati Chandratre, Siddharth Sinha, Jian Cui, Teng Huang, Xiaobing Wu, Michael Q. Zhang, San Ming Wang, Hemant Gupta
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-12 (2020)
BMC Genomics
BMC Genomics
Background Core promoter controls transcription initiation. However, little is known for core promoter diversity in the human genome and its relationship with diseases. We hypothesized that as a functional important component in the genome, the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f6d23b9d0b9d5b7819ed3d04ab6b4d
https://doi.org/10.1186/s12864-020-07222-5
https://doi.org/10.1186/s12864-020-07222-5
Autor:
Hui, Dong, Khyati, Chandratre, Yue, Qin, Jing, Zhang, Xiaoqing, Tian, Ce, Rong, Ning, Wang, Maoni, Guo, Guoping, Zhao, San Ming, Wang
Publikováno v:
Journal of medical genetics. 58(8)
Pathogenic variation inIn this study, we usedWe identified 1209Our study provides basic knowledge about the prevalence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9a4c7723f047ea4c9bd94b8b031d9ac
https://pubmed.ncbi.nlm.nih.gov/32467295
https://pubmed.ncbi.nlm.nih.gov/32467295
Autor:
Ommega Internationals, Barkha Shah, Spandan Chaudhary, Arpita Ghosh, Srinivas Vudathala, Dipali Dhawan, Khyati Chandratre, Prashanth G. Bagali
Publikováno v:
Journal of Bioinformatics and Proteomics Review. 2:1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978b7261aac1d510c56bedbf69173ec5
https://doi.org/10.15436/2381-0793.16.1093
https://doi.org/10.15436/2381-0793.16.1093
Autor:
Niraj Sojitra, Spandan Chaudhary, Dipali Dhawan, Sandip Hirapara, Khyati Chandratre, Arpita Ghosh, Prashanth G. Bagali, Sanjay Singh
Publikováno v:
Clinical & Medical Biochemistry Open Access.
Co-inheritance of sickle cell anemia and β-thalassemia traits require medical attention. Individuals with sickle cell and β-thalassemia disorders produce abnormal form of hemoglobin or decreased synthesis or complete absence of the β-globin chains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d397138ffec9d853750d1d74b33bbd5
https://doi.org/10.4172/2471-2663.1000108
https://doi.org/10.4172/2471-2663.1000108