Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Khuzwayo C. Jere"'
Autor:
Chrispin Chaguza, Innocent Chibwe, David Chaima, Patrick Musicha, Latif Ndeketa, Watipaso Kasambara, Chimwemwe Mhango, Upendo L. Mseka, Joseph Bitilinyu-Bangoh, Bernard Mvula, Wakisa Kipandula, Patrick Bonongwe, Richard J. Munthali, Selemani Ngwira, Chikondi A. Mwendera, Akuzike Kalizang’oma, Kondwani C. Jambo, Dzinkambani Kambalame, Arox W. Kamng’ona, A. Duncan Steele, Annie Chauma-Mwale, Daniel Hungerford, Matthew Kagoli, Martin M. Nyaga, Queen Dube, Neil French, Chisomo L. Msefula, Nigel A. Cunliffe, Khuzwayo C. Jere
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Malawi experienced its deadliest Vibrio cholerae (Vc) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths reported between March 2022 and May 2023. Here, we use population genomics to investigate the attributes and o
Externí odkaz:
https://doaj.org/article/6b7cbc3890c14711a1a922c4cd6b9c0a
Autor:
Cindy X. Zhang, Thomas M. Conrad, David Hermann, Melita A. Gordon, Eric Houpt, Pui‐Ying Iroh Tam, Khuzwayo C. Jere, Wilfred Nedi, Darwin J. Operario, Jacob Phulusa, Gerald V. Quinnan Jr, Leigh A. Sawyer, Lynn K. Barrett, Herbert Thole, Neema Toto, Wesley C. Van Voorhis, Samuel L. M. Arnold
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 3, Pp 410-423 (2024)
Abstract Oral drug absorption kinetics are usually established in populations with a properly functioning gastrointestinal tract. However, many diseases and therapeutics can alter gastrointestinal physiology and cause diarrhea. The extent of diarrhea
Externí odkaz:
https://doaj.org/article/eb41958c05d84d0fb5af26988b5b95cf
Autor:
Kayla G. Barnes, Joshua I. Levy, Jillian Gauld, Jonathan Rigby, Oscar Kanjerwa, Christopher B. Uzzell, Chisomo Chilupsya, Catherine Anscombe, Christopher Tomkins-Tinch, Omar Mbeti, Edward Cairns, Herbert Thole, Shannon McSweeney, Marah G. Chibwana, Philip M. Ashton, Khuzwayo C. Jere, John Scott Meschke, Peter Diggle, Jennifer Cornick, Benjamin Chilima, Kondwani Jambo, Kristian G. Andersen, Gift Kawalazira, Steve Paterson, Tonney S. Nyirenda, Nicholas Feasey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The COVID-19 pandemic has profoundly impacted health systems globally and robust surveillance has been critical for pandemic control, however not all countries can currently sustain community pathogen surveillance programs. Wastewater survei
Externí odkaz:
https://doaj.org/article/d44d0de541934d628984d02c52f9cee8
Autor:
Edward Cunningham-Oakes, Christina Bronowski, End Chinyama, Khuzwayo C. Jere, Kulandaipalayam Natarajan C. Sindhu, Gagandeep Kang, Miren Iturriza-Gómara, Alistair C. Darby, Edward P. K. Parker
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract The immunogenicity and effectiveness of oral rotavirus vaccines (ORVs) against severe rotavirus-associated gastroenteritis are impaired in low- and middle-income countries (LMICs) where the burden of disease is highest. Determining risk fact
Externí odkaz:
https://doaj.org/article/e4ea628f8cd740bebab83045b90cc14f
Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets
Autor:
Chikondi Malamba-Banda, Chimwemwe Mhango, Prisca Benedicto-Matambo, Jonathan J. Mandolo, End Chinyama, Orpha Kumwenda, Kayla G. Barnes, Nigel A. Cunliffe, Miren Iturriza-Gomara, Kondwani C. Jambo, Khuzwayo C. Jere
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Strong CD4+ T cell-mediated immune protection following rotavirus infection has been observed in animal models, but its relevance in humans remains unclear. Here, we characterized acute and convalescent CD4+ T cell responses in children who
Externí odkaz:
https://doaj.org/article/f54a11022a924976af074cef85e6c85f
Autor:
Upendo L. Mseka, Jonathan Mandolo, Kenneth Nyoni, Oscar Divala, Dzinkambani Kambalame, Daniel Mapemba, Moses Kamzati, Innocent Chibwe, Marc Y.R. Henrion, Kingsley Manda, Deus Thindwa, Memory Mvula, Bright Odala, Raphael Kamng'ona, Nelson Dzinza, Khuzwayo C. Jere, Nicholas Feasey, Antonia Ho, Abena S. Amoah, Melita Gordon, Todd D. Swarthout, Amelia Crampin, Robert S. Heyderman, Matthew Kagoli, Evelyn Chitsa-Banda, Collins Mitambo, John Phuka, Benson Chilima, Watipaso Kasambara, Kondwani C. Jambo, Annie Chauma-Mwale
Publikováno v:
EClinicalMedicine, Vol 56, Iss , Pp 101800- (2023)
Summary: Background: The B.1.1.529 (Omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the fourth COVID-19 pandemic wave across the southern African region, including Malawi. The seroprevalence of SARS-Co
Externí odkaz:
https://doaj.org/article/d886e6a896034979824c21646a6c6ea9
Autor:
Edward P. K. Parker, Christina Bronowski, Kulandaipalayam Natarajan C. Sindhu, Sudhir Babji, Blossom Benny, Noelia Carmona-Vicente, Nedson Chasweka, End Chinyama, Nigel A. Cunliffe, Queen Dube, Sidhartha Giri, Nicholas C. Grassly, Annai Gunasekaran, Deborah Howarth, Sushil Immanuel, Khuzwayo C. Jere, Beate Kampmann, Jenna Lowe, Jonathan Mandolo, Ira Praharaj, Bakthavatsalam Sandya Rani, Sophia Silas, Vivek Kumar Srinivasan, Mark Turner, Srinivasan Venugopal, Valsan Philip Verghese, Alistair C. Darby, Gagandeep Kang, Miren Iturriza-Gómara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Oral rotavirus vaccine (ORV) efficacy varies between countries, but underlying reasons aren’t fully understood. In this prospective cohort study, authors show that maternal rotavirus-specific antibodies in serum and breastmilk and pre-vaccination m
Externí odkaz:
https://doaj.org/article/d77c8ef898934e4e9eef567e35f7d027
Autor:
Josephine Bwogi, Charles Karamagi, Denis Karuhize Byarugaba, Phionah Tushabe, Sarah Kiguli, Prossy Namuwulya, Samuel S. Malamba, Khuzwayo C. Jere, Ulrich Desselberger, Miren Iturriza-Gomara
Publikováno v:
Viruses, Vol 15, Iss 3, p 738 (2023)
Rotavirus genotypes are species specific. However, interspecies transmission is reported to result in the emergence of new genotypes. A cross-sectional study of 242 households with 281 cattle, 418 goats, 438 pigs, and 258 humans in Uganda was underta
Externí odkaz:
https://doaj.org/article/5105381c68394591831ce4003ecb7d89
Autor:
Frederick N. Were, Khuzwayo C. Jere, George E. Armah, M. Jeffrey Mphahlele, Jason M. Mwenda, A. Duncan Steele
Publikováno v:
Vaccines, Vol 10, Iss 9, p 1463 (2022)
The 13th African Rotavirus Symposium was held as a virtual event hosted by the University of Nairobi, Kenya and The Kenya Paediatric Association on 3rd and 4th November 2021. This biennial event organized under the auspices of the African Rotavirus N
Externí odkaz:
https://doaj.org/article/72ebc5502b00495ea35576590d551e18
Autor:
Khuzwayo C. Jere, Naor Bar-Zeev, Adams Chande, Aisleen Bennett, Louisa Pollock, Pedro F. Sanchez-Lopez, Osamu Nakagomi, Jacqueline E. Tate, Umesh D. Parashar, Robert S. Heyderman, Neil French, Miren Iturriza-Gomara, Nigel A. Cunliffe
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 9, Pp 1734-1737 (2019)
Atypical DS-1–like G1P[8] rotaviruses emerged in 2013 in Malawi after rotavirus vaccine introduction. Vaccine effectiveness among infants hospitalized with acute DS-1–like G1P[8] rotavirus gastroenteritis was 85.6% (95% CI 34.4%–96.8%). These f
Externí odkaz:
https://doaj.org/article/1441846bc0354b37830202bd3c8ec33d