Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Khushnuma Wahabi"'
Autor:
Khushnuma Wahabi, Ahmad Perwez, Shabeena Kamarudheen, Zafar Iqbal Bhat, Anurag Mehta, M. Moshahid A. Rizvi
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Parkin in breast canc
Externí odkaz:
https://doaj.org/article/fec4d6f281274a199e7fa20f18f52461
Autor:
Bhupender Kumar, Zafar Iqbal Bhat, Savita Bansal, Sunil Saini, Afreen Naseem, Khushnuma Wahabi, Archana Burman, Geeta Trilok Kumar, Sundeep Singh Saluja, M Moshahid Alam Rizvi
Publikováno v:
Tumor Biology, Vol 39 (2017)
Globally, colorectal cancer is the third most common type of cancer. Genetic instability leading to cancer development is one of the major causes for development of cancer. Alterations in mitochondrial genome, that is, mutations, single-nucleotide po
Externí odkaz:
https://doaj.org/article/b56dc0d762d846c088b2a2b21e82d0d9
Autor:
Raj Ranjan Tiwari, Hasan Ss, Meher Rizvi, Sundeep Singh Saluja, Ahmad Perwez, Khushnuma Wahabi, Zafar Iqbal Bhat
Publikováno v:
Turk J Gastroenterol
BACKGROUND/AIMS: Alterations in Parkin (PRKN) have been described in many cancers; however, the molecular mechanism that contributes to loss of Parkin expression in colorectal cancer (CRC) remains unclear. The aim of this study was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21209d98ec8f22647a370fa060563758
https://doi.org/10.5152/tjg.2020.18823
https://doi.org/10.5152/tjg.2020.18823
Publikováno v:
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811654213
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b0aa6a15315393eb2a81348b7c1006
https://doi.org/10.1007/978-981-16-5422-0_5
https://doi.org/10.1007/978-981-16-5422-0_5
Autor:
Zafar Iqbal Bhat, Gaurav Sharma, Savita Bansal, Afreen Naseem, Raj Ranjan Tiwari, Bupender Kumar, Meher Rizvi, Khushnuma Wahabi
Publikováno v:
Gene. 682:25-32
Different diseases have been associated with PARK2/PACRG overlapping promoter polymorphisms (rs2276201 and rs9347683) in the recent past. However association of these polymorphisms with cancer remains elusive till date. Thus in this study we evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13d8509d667e6fd412576d257733057
https://doi.org/10.1016/j.gene.2018.10.010
https://doi.org/10.1016/j.gene.2018.10.010
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Breast cancer is a heterogeneous disease that can be subdivided on the basis of histopathological features, genetic alterations, and gene-expression profiles. PTEN gene is considered an established tumor suppressor gene in different types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cc592a26c0f48c312226f73605bd96
https://doi.org/10.31557/apjcp.2019.20.1.269
https://doi.org/10.31557/apjcp.2019.20.1.269
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1876(1)
Parkin, an E3 ubiquitin ligase has been found to be deregulated in a variety of human cancers. Our current understanding is endowed with strong evidences that Parkin plays crucial role in the pathogenesis of cancer by controlling/interfering with maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2aec54ee7417a4ad8b1c3befce21db
https://pubmed.ncbi.nlm.nih.gov/33785381
https://pubmed.ncbi.nlm.nih.gov/33785381
Autor:
Meher Rizvi, Zafar Iqbal Bhat, Khushnuma Wahabi, Anurag Mehta, Shabeena Kamarudheen, Ahmad Perwez
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
BMC Cancer
BMC Cancer
Background Progression of breast cancer involves both genetic and epigenetic factors. Parkin gene has been identified as a tumor suppressor gene in the pathogenesis of various cancers. Nevertheless, the putative role of Parkin in breast cancer remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd09fd49fd2ef7ecddf37f6624f3a51
https://doi.org/10.1186/s12885-019-6013-6
https://doi.org/10.1186/s12885-019-6013-6
Table S1 Clinicopathological characteristics of breast cancer patients included for the study (Nâ =â 156). Table S2 Representative table of primer sequence for PCR and their respective temperature 558 and amplicon size. Table S3 Summary of mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63df2b8045033788ec3f77fd0fd57eba
Figure S1 PARK2 alterations. Figure S2 PARK2 mutations. Figure S3 PARK2 mutations in COSMIC. Figure S4 A. Oncomine analysis showed loss of Parkin expression in different types of breast carcinoma cell line in comparison to other cancer cell lines usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218599c0a5a2e8d020124b3238934a49