Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Khushnooma Italia"'
Publikováno v:
Pediatric Hematology Oncology Journal, Vol 2, Iss 4, Pp 79-84 (2017)
The thalassemias and structural haemoglobin variants are the commonest monogenic disorders globally. India has a huge burden with an estimated 100,000 patients with a β thalassemia syndrome and around 150,000 patients with sickle cell disease, but f
Externí odkaz:
https://doaj.org/article/84dee5f10fa74fe9a260d2b29699ef6b
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82928 (2013)
Our previous study showed a reduction in serum ferritin of β-thalassemia patients on hydroxyurea therapy. Here we aimed to evaluate the efficacy of hydroxyurea alone and in combination with most widely used iron chelators like deferiprone and defera
Externí odkaz:
https://doaj.org/article/1853a7cb27694ada87850c1e2721908a
Autor:
Pratibha Sawant, Pallavi Mehta, Kanjaksha Ghosh, Manju Gorivale, Dipti Upadhye, Roshan B. Colah, Ajit Gorakshakar, Priya Hariharan, Khushnooma Italia, Anita Nadkarni
Publikováno v:
International Journal of Laboratory Hematology. 41:218-226
Introduction The hemoglobinopathies pose a significant health burden in India. Apart from the β thalassemias and sickle cell disorders, α thalassemias and structural hemoglobin variants are also common. Here we have reviewed the phenotypic and mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600efbafb2b2ff496ba63584223b591c
https://doi.org/10.1111/ijlh.12948
https://doi.org/10.1111/ijlh.12948
Autor:
G. Subramanian, Priya Hariharan, Dipti Upadhye, Khushnooma Italia, Pratibha Sawant, Pallavi Mehta, Anita Nadkarni, Malay B. Mukherjee
Publikováno v:
International Journal of Laboratory Hematology. 39:e51-e54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c791215109f743fdad0ea07aedbd0c
https://doi.org/10.1111/ijlh.12608
https://doi.org/10.1111/ijlh.12608
Publikováno v:
Free Radical Research. 50:959-965
In this study, we hypothesize that hydroxyurea could provide an additional benefit as a free radical scavenger and/or iron chelator in β-thalassemia patients with iron overload. Twenty-one β-thalassemia intermedia patients who presented between 3 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ba428126fb6e35f0ec20f6647ac1e1
https://doi.org/10.1080/10715762.2016.1209497
https://doi.org/10.1080/10715762.2016.1209497
Autor:
Kanjaksha Ghosh, Mamta Manglani, Manisha Madkaikar, Surjit Singh, Snehal Mhatre, Sushant Chavan, Deepti Suri, Amita Agrawal, Khushnooma Italia, Anju Mishra, Meghna Rao, Mukesh Desai, Maya Gupta
Publikováno v:
Blood Cells, Molecules, and Diseases. 54:217-223
Purpose Leukocyte adhesion deficiency type-I (LAD-I) is caused by mutations in the ITGB2 gene, encoding the β 2 -subunit of β 2 -integrin (CD18) which leads to markedly reduced expression of CD18 on leukocytes resulting into recurrent life threaten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f66dbd6b9366e92d2f539cf965dc5b
https://doi.org/10.1016/j.bcmd.2015.01.012
https://doi.org/10.1016/j.bcmd.2015.01.012
Autor:
Harshali Gaikwad, Kanjaksha Ghosh, Dipti Upadhye, Pratibha Sawant, Ajit Gorakshakar, Khushnooma Italia, Anita Nadkarni, Roshan B. Colah
Publikováno v:
Indian journal of hematologyblood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion. 34(3)
The clinical presentation of HbE-β-thalassemia is extremely variable, however, many cases are severe and transfusion dependent. We offered prenatal diagnosis to 108 couples, 20 of whom came prospectively. CVS was done in 93 cases (9.5–13 weeks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f43d4b31b86c4fbf46f136f5642be02
https://pubmed.ncbi.nlm.nih.gov/30127556
https://pubmed.ncbi.nlm.nih.gov/30127556
Autor:
Pallavi Mehta, Roshan B. Colah, Bhavesh Raicha, Lakshmanan Krishnamurti, Vishal Mehta, Kanjaksha Ghosh, Khushnooma Italia, Yazdi M. Italia
Publikováno v:
Journal of Medical Screening. 22:1-7
Objectives To evaluate the feasibility of a newborn screening and follow-up programme for sickle cell disease (SCD) among tribal populations of south Gujarat, India. Methods A total of 5467 newborn babies were screened over 2 years using High-perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b7866938b3eb72150988f55a14057d
https://doi.org/10.1177/0969141314557372
https://doi.org/10.1177/0969141314557372
Autor:
Kanjaksha Ghosh, Harshada K. Kangne, Chandrakala Shanmukaiah, Khushnooma Italia, Anita Nadkarni, Roshan B. Colah
Publikováno v:
British Journal of Haematology. 168:156-159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f466683503f8b6ac6cba20f25fcf468e
https://doi.org/10.1111/bjh.13083
https://doi.org/10.1111/bjh.13083
Autor:
Roshan B. Colah, Dipti Upadhye, Pratibha Sawant, Dipty Jain, Pooja Dabke, Ajit Gorakshakar, Yazdi M. Italia, Harshada Kangane, Stacy Colaco, Kanjaksha Ghosh, Khushnooma Italia, Anita Nadkarni
Publikováno v:
Clinica Chimica Acta. 431:46-51
Background Co-inheritance of structural hemoglobin variants like HbS, HbD Punjab and HbE can lead to a variable clinical presentation and only few cases have been described so far in the Indian population. Methods We present the varied clinical and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052f9f0ad287d0701521397710adffde
https://doi.org/10.1016/j.cca.2014.01.028
https://doi.org/10.1016/j.cca.2014.01.028