Výsledky vyhledávání - "Khushin N. Patel"

Membrane Estrogen Receptor β Is Sufficient to Mitigate Cardiac Cell Pathology

Autor: Amrita Ahluwalia, Neil Hoa, Debbie Moreira, Daniel Aziz, Karanvir Singh, Khushin N Patel, Ellis R Levin

Publikováno v: Endocrinology. 164(2)

Estrogen acting through estrogen receptor β (ERβ) has been shown to oppose the stimulation of cardiac myocytes and cardiac fibroblasts that results in cardiac hypertrophy and fibrosis. Previous work has implicated signal transduction from ERβ as b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46262dedadf87aed5b31127106fbf5c1
https://pubmed.ncbi.nlm.nih.gov/36461668

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Melatonin ameliorates aging-related impaired angiogenesis in gastric endothelial cells via local actions on mitochondria and VEGF-survivin signaling

Autor: Amrita Ahluwalia, Andrzej S. Tarnawski, Iwona Brzozowska, Neil Hoa, Khushin N. Patel, Michael K. Jones

Tissue injury healing is impaired in aging, and this impairment is caused in part by reduced angiogenesis. Melatonin, a neuroendocrine hormone that regulates sleep and circadian rhythm, is also produced in the gastrointestinal tract. The expression o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adea1d22ffd15fb243b4372ec7c55267
https://ruj.uj.edu.pl/xmlui/handle/item/285366

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STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration

Autor: Khushin N. Patel, Sandor Szabo, Xiaoming Deng, Zsuzsanna Sandor, Andrzej S. Tarnawski, Tetyana Khomenko, Amrita Ahluwalia

Publikováno v: Digestive diseases and sciences. 59(2)

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that directly upregulates VEGF, Ref-1, p21, and anti-apoptotic genes such as Bcl-xL. In this study, we hypothesized that STAT3 signaling is activated and provides a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b18181143b594595d9f09db0d436e90
https://pubmed.ncbi.nlm.nih.gov/24385009

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