Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Khushboo Irshad"'
Autor:
Khushboo Irshad, Yu-Kai Huang, Paul Rodriguez, Jung Lo, Benjamin E. Aghoghovwia, Yuan Pan, Kun-Che Chang
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1424 (2023)
Optic pathway glioma (OPG) is one of the causes of pediatric visual impairment. Unfortunately, there is as yet no cure for such a disease. Understanding the underlying mechanisms and the potential therapeutic strategies may help to delay the progress
Externí odkaz:
https://doaj.org/article/6381f47f701e439a90a00025f277b509
Autor:
Khushboo Irshad, Chitrangda Srivastava, Nargis Malik, Manvi Arora, Yakhlesh Gupta, Sanjeev Goswami, Chitra Sarkar, Vaishali Suri, Swati Mahajan, Deepak Kumar Gupta, Ashish Suri, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
FAT atypical cadherin 1 (FAT1) promotes glioblastoma (GBM) by promoting protumorigenic inflammatory cytokine expression in tumor cells. However, tumors also have an immunosuppressive microenvironment maintained by mediators such as transforming growt
Externí odkaz:
https://doaj.org/article/03997060fde24d64906940201c95d3ae
Autor:
Chitrangda Srivastava, Khushboo Irshad, Yakhlesh Gupta, Chitra Sarkar, Ashish Suri, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-18 (2020)
Abstract Background Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1 gene in glioblastoma (GBM) tumors which was found to increase the expression of proin
Externí odkaz:
https://doaj.org/article/078ab417c9454ac4a436c40ebed30aaa
Publikováno v:
Translational Oncology, Vol 14, Iss 7, Pp 101097- (2021)
A recent study in Scientific Reports identified glypican-3 (GPC3) as a novel extracellular interacting protein for FAT1 in hepato-cellular carcinoma (HCC) cells. FAT1 is a large transmembrane atypical cadherin with limited knowledge existing about it
Externí odkaz:
https://doaj.org/article/6f7b0409115142be846042796af705cf
Publikováno v:
Annals of the National Academy of Medical Sciences (India), Vol 51, Iss 4, Pp 125-139 (2015)
Conventional classification of tumors, especially in terms of staging and grading is of immense importance for both prognostication as well as management strategies. However it is not a perfect system and there are many instances where tumor behaviou
Externí odkaz:
https://doaj.org/article/d8c3210e5eb945c7a7f2e1ad66672e21
Autor:
Khushboo Irshad, Saroj Kant Mohapatra, Chitrangda Srivastava, Harshit Garg, Seema Mishra, Bhawana Dikshit, Chitra Sarkar, Deepak Gupta, Poodipedi Sarat Chandra, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118201 (2015)
Hypoxia is a hallmark of solid tumors including glioblastoma (GBM). Its synergism with Notch signaling promotes progression in different cancers. However, Notch signaling exhibits pleiotropic roles and the existing literature lacks a comprehensive un
Externí odkaz:
https://doaj.org/article/7eaa05ba853a4fef842c32732147ae93
Autor:
Kunzang Chosdol, Subrata Sinha, Chitra Sarkar, Chitrangda Srivastava, Parthaprasad Chattopadhyay, Ashish Suri, Khushboo Irshad, Yakhlesh Gupta
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-18 (2020)
BMC Cancer
BMC Cancer
Background Overexpression of FAT1 gene and its oncogenic effects have been reported in several cancers. Previously, we have documented upregulation of FAT1 gene in glioblastoma (GBM) tumors which was found to increase the expression of proinflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0749d1e69b697faff5e73db40815457d
https://doaj.org/article/078ab417c9454ac4a436c40ebed30aaa
https://doaj.org/article/078ab417c9454ac4a436c40ebed30aaa
Publikováno v:
Translational Oncology, Vol 14, Iss 7, Pp 101097-(2021)
Translational Oncology
Translational Oncology
A recent study in Scientific Reports identified glypican-3 (GPC3) as a novel extracellular interacting protein for FAT1 in hepato-cellular carcinoma (HCC) cells. FAT1 is a large transmembrane atypical cadherin with limited knowledge existing about it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d16b235ca31683abbf42554ed5af0f
http://www.sciencedirect.com/science/article/pii/S1936523321000899
http://www.sciencedirect.com/science/article/pii/S1936523321000899
Publikováno v:
Journal of Applied Biology & Biotechnology.
COVID-19 continues to pose a global public health emergency several months after the first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (then referred to as novel coronavirus [2019-nCoV]) infection were reported in Wuhan, Chi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9fa551e5fadf6210a1c1bd1d50b74c3
https://doi.org/10.7324/jabb.2021.9113
https://doi.org/10.7324/jabb.2021.9113
Autor:
Kunzang Chosdol, Khushboo Irshad, Chitra Sarkar, Chitrangda Srivastava, Deepak Gupta, Bhawana Dikshit, Parthaprasad Chattopadhyay, Subrata Sinha
Publikováno v:
International Journal of Cancer. 142:805-812
Glioblastoma (GBM) is characterized by the presence of hypoxia, stemness and local invasiveness. We have earlier demonstrated that FAT1 promotes invasiveness, inflammation and upregulates HIF-1α expression and its signaling in hypoxic GBM. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a5da5fee4499c7ec057caf0b0e0ab5c
https://doi.org/10.1002/ijc.31092
https://doi.org/10.1002/ijc.31092