Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Khuloud T. Al Jamal"'
Autor:
Julie Tzu‐Wen Wang, Ana C. Rodrigo, Anna K. Patterson, Kirsten Hawkins, Mazen M. S. Aly, Jia Sun, Khuloud T. Al Jamal, David K. Smith
Publikováno v:
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Abstract This paper reports the use of a self‐assembling hydrogel as a delivery vehicle for the Parkinson's disease drug l‐DOPA. Based on a two‐component combination of an l‐glutamine amide derivative and benzaldehyde, this gel has very soft
Externí odkaz:
https://doaj.org/article/9b5c63cf8a0442d7a18de51759da4d45
Autor:
Emine Yavuz, Adam A. Walters, Bhavnesh V. Chudasama, Shunping Han, Yue Qin, Khuloud T. Al‐Jamal
Publikováno v:
Advanced Materials Interfaces, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Metal nanoparticles (NPs) are suggested as a vaccine delivery platform. At present, there is limited description of cuboidal Ag nanocubes (AgNCs; nonporous) and Au nanocages (AuNCs; porous) as a protein carrier for vaccination. Here, the int
Externí odkaz:
https://doaj.org/article/9d0856de66d94ccdb2f666d24d54b103
Autor:
Rosalind Graham, Patrycja Gazinska, Birong Zhang, Atousa Khiabany, Shubhankar Sinha, Thanussuyah Alaguthurai, Fabian Flores-Borja, Jose Vicencio, Fabienne Beuron, Ioannis Roxanis, Rafal Matkowski, Revadee Liam-Or, Andrew Tutt, Tony Ng, Khuloud T. Al-Jamal, You Zhou, Sheeba Irshad
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIntracellular communication within the tumour is complex and extracellular vesicles (EVs) have been identified as major contributing factors for the cell-to-cell communication in the local and distant tumour environments. Here, we examine t
Externí odkaz:
https://doaj.org/article/6751835215264410a344fd60c77e7254
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 7, Pp 419-433 (2020)
Abstract Stem cell‐derived exosomes have been identified as novel cell‐free therapeutics for regenerative medicine. Three‐dimensional (3D) culture of stem cells were reported to improve their “stemness” and therapeutic efficacy. This work f
Externí odkaz:
https://doaj.org/article/8ba88eee051c4e00896faef264a24099
Autor:
Shunping Han, Julie Tzu-Wen Wang, Emine Yavuz, Alaa Zam, Nadia Rouatbi, Rifka Nurul Utami, Revadee Liam-Or, Alexander Griffiths, Wayne Dickson, Jane Sosabowski, Khuloud T. Al-Jamal
Publikováno v:
Journal of Controlled Release. 357:606-619
Autor:
Sim Lai Tung, Giorgia Fanelli, Robert Ian Matthews, Jordan Bazoer, Marilena Letizia, Gema Vizcay-Barrena, Farid N. Faruqu, Christina Philippeos, Rosalind Hannen, Khuloud T. Al-Jamal, Giovanna Lombardi, Lesley Ann Smyth
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Regulatory T cells (Tregs) are a subpopulation of CD4+ T cells with a fundamental role in maintaining immune homeostasis and inhibiting unwanted immune responses using several different mechanisms. Recently, the intercellular transfer of molecules be
Externí odkaz:
https://doaj.org/article/773536993a454f9fa1748b7fa66718d4
Autor:
Mohamed Hamdi, Enas Elmowafy, Hend Mohamed Abdel-Bar, Akram M. ElKashlan, Khuloud T. Al-Jamal, Gehanne A.S. Awad
Publikováno v:
International Journal of Biological Macromolecules. 217:731-747
Drug covalently bound to polymers had formed, lately, platforms with great promise in drug delivery. These drug polymer conjugates (DPC) boosted drug loading and controlled medicine release with targeting ability. Herein, the ability of entecavir (E)
Publikováno v:
Biomaterials Science. 10:3410-3432
Non-viral delivery technologies for efficient in vivo Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR/Cas9) gene editing.
Autor:
Dina O. Helal, Adam A. Walters, Mona M.A. Abdel-Mottaleb, Khuloud T. Al-Jamal, Shunping Han, Julie Tzu-Wen Wang, Amany O. Kamel, Nadia Rouatbi, Ahmed-Shawky Geneidi, Gehanne A.S. Awad
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 169:297-308
Glioblastoma is one of the most difficult to treat cancers with poor prognosis and survival of around one year from diagnosis. Effective treatments are desperately needed. This work aims to prepare temozolomide acid (TMZA) loaded albumin nanoparticle
Publikováno v:
Drug delivery and translational research.
In situ vaccination with immunostimulatory compounds is a demonstrated means to treat tumors preclinically. While these therapeutic effects have been attributed to the actions of T cells or innate immune activation, characterisation of the humoral im