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pro vyhledávání: '"Khue Vu Nguyen"'
Autor:
Khue Vu Nguyen
Publikováno v:
AIMS Neuroscience, Vol 9, Iss 2, Pp 175-215 (2022)
A heterozygous Arg393His point mutation at the reactive site of antithrombin (AT) gene causing thrombosis in a Vietnamese patient is reported and named as Arg393His in AT-Hanoi. The present variant is characterized by a severe reduction of functional
Externí odkaz:
https://doaj.org/article/1f5c51639c4a4885a406cbcd8a40b05c
Autor:
Khue Vu Nguyen
Publikováno v:
AIMS Neuroscience, Vol 8, Iss 4, Pp 548-557 (2021)
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorders of purine metabolic in which the cytoplasmic enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. Despite having been characterized over 60 years ag
Externí odkaz:
https://doaj.org/article/87a45eae98444dcf8a8626b01e50e7e2
Autor:
Khue Vu Nguyen
Publikováno v:
AIMS Neuroscience, Vol 6, Iss 4, Pp 273-281 (2019)
Several pathophysiological functions of the human β-amyloid precursor protein (APP) have been recently proposed in different human diseases such as neurodevelopmental and neurodegenerative disorders including rare diseases such as autism, fragile X
Externí odkaz:
https://doaj.org/article/34d9732c2ac04869a51dd02fb1f30282
Autor:
Khue Vu Nguyen
Publikováno v:
AIMS Neuroscience, Vol 5, Iss 1, Pp 74-80 (2018)
More than 45 million people worldwide have Alzheimer’s disease (AD), a deterioration of memory and other cognitive domains that leads to death within 3 to 9 years after diagnosis. The principal risk factor for AD is age. As the aging population inc
Externí odkaz:
https://doaj.org/article/2f44048cfd444b76a7af913d8473f03e
Autor:
Khue Vu, Nguyen
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 41:778-814
Viruses have multiple mutation rates that are higher than any other member of the kingdom of life. This gives them the ability to evolve, even within the course of a single infection, and to evade multiple host defenses, thereby impacting pathogenesi
Autor:
Khue Vu Nguyen
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The outbreak of a novel coronavirus responsible for the severe acquired respiratory syndrome: SARS-CoV-2, also known as coronavirus disease 2019: COVID-19, represents a pandemic threat that has been declared a public health emergency of international
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 39:905-922
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorder of purine metabolism in which the enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. Despite having been characterized over 50 years ago, it remain
Autor:
Khue Vu Nguyen
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 38:752-780
The purpose of this review is to highlight the impact of the alternative splicing process on human disease. Epigenetic regulation determines not only what parts of the genome are expressed but also how they are spliced. The recent progress in the fie
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 36:452-462
Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorder of purine metabolism in which the enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. The authors report two independent point mutations leading to
Autor:
William L. Nyhan, Khue Vu Nguyen
Publikováno v:
Neuroscience Letters. 643:52-58
The present work is the development of a simple and specific kinetic method based on RT-PCR technique coupled with direct sequencing for quantification of various amyloid precursor protein-mRNA isoforms (APP-mRNA isoforms) in biological samples, espe