Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Khuda Dad Khan"'
Publikováno v:
Lahore Garrison University Journal of Life Sciences. 5:211-218
The present study was designed to identify the level of Ischemic Heart Disease (IHD) with reference to various risk factors. This was a case-control study thatwas used to develop a predictive model for the risk of IHD in various conditions. Complete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c032dd13d6a93ea4489dc4715066304f
https://doi.org/10.54692/lgujls.2021.0503179
https://doi.org/10.54692/lgujls.2021.0503179
Autor:
Verena Karsten, Khuda Dad Khan, William Tse, Anjali S. Advani, Ann Cahill, Samantha LoRusso, Joseph O. Moore, David A. Rizzieri, Stanton L. Gerson
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 10:211-216
Purpose Although alkylators are known to be effective against some myeloid leukemias, resistance is often mediated via O 6 -alkylguanine-DNA alkyltransferase (AGT). Temozolomide's inhibition of AGT may sensitize leukemia cells to the novel alkylator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c88b1edd557949bcf8baa0d86f7cd1d
https://doi.org/10.3816/clml.2010.n.033
https://doi.org/10.3816/clml.2010.n.033
Publikováno v:
Journal of Biological Chemistry. 275:22583-22589
The receptor for insulin-like growth factor 1 (IGF-1) mediates multiple cellular responses, including stimulation of both proliferative and anti-apoptotic pathways. We have examined the role of cross talk between the IGF-1 receptor (IGF-1R) and the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acabf3729733fc21438df1216d8976f0
https://doi.org/10.1074/jbc.m002915200
https://doi.org/10.1074/jbc.m002915200
Autor:
William E. Miller, Stuart Maudsley, Louis M. Luttrell, Khuda Dad Khan, Seungkirl Ahn, Robert J. Lefkowitz
Publikováno v:
Journal of Biological Chemistry. 275:11312-11319
β-Arrestins can act as adapter molecules, coupling G-protein-coupled receptors to proteins involved in mitogenic as well as endocytic pathways. We have previously identified c-SRC as a molecule that is rapidly recruited to the β2-adrenergic recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc4188517a2fadd8cafab79ae629240
https://doi.org/10.1074/jbc.275.15.11312
https://doi.org/10.1074/jbc.275.15.11312
Publikováno v:
The Journal of Immunology. 163:811-819
The complexity of IFN-mediated regulation of the murine Ly-6E gene in T cell lines is highlighted by the following observations: 1) multiple regulatory regions are present within different parts of the Ly-6E promoter and are necessary for IFN inducib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e2d32c599abda01e8944940edd4ba0
https://doi.org/10.4049/jimmunol.163.2.811
https://doi.org/10.4049/jimmunol.163.2.811
Publikováno v:
Blood. 92:2399-2409
The murine Ly6-E gene is transcriptionally induced by interferon-α/β (IFN-α/β) and IFN-γ in a variety of distinct cell types. The mechanism of IFN inducibility in B-cell lines was investigated by deletion analysis of the promoter and by identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f595f85de5040a5a4e7f475d1ab9cace
https://doi.org/10.1182/blood.v92.7.2399.2399_2399_2409
https://doi.org/10.1182/blood.v92.7.2399.2399_2399_2409
Publikováno v:
Blood. 92:2399-2409
The murine Ly6-E gene is transcriptionally induced by interferon-α/β (IFN-α/β) and IFN-γ in a variety of distinct cell types. The mechanism of IFN inducibility in B-cell lines was investigated by deletion analysis of the promoter and by identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::436a4a9115d01cacf358ca04c1191a72
https://doi.org/10.1182/blood.v92.7.2399
https://doi.org/10.1182/blood.v92.7.2399
Autor:
Glen Lindwall, Ke Shuai, Stephen E. Maher, Khuda Dad Khan, J. E. Darnell, Alfred L. M. Bothwell
Publikováno v:
Proceedings of the National Academy of Sciences. 90:6806-6810
The murine Ly-6A/E gene is transcriptionally induced in cells exposed to interferon alpha/beta or gamma (IFN-alpha/beta or IFN-gamma). Analysis of the 5' flanking sequence using reporter plasmids that contain upstream elements of the Ly-6E gene has p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4344638b70cce78f0170c596fd3ddb
https://doi.org/10.1073/pnas.90.14.6806
https://doi.org/10.1073/pnas.90.14.6806
Autor:
Syed Fazl Ali Bilgrami, Maher Albitar, Ann Cahill, Gregor Verhoef, Susan O'Brien, David A. Rizzieri, Anjali S. Advani, Ghulam J. Mufti, Judith E. Karp, Hagop M. Kantarjian, Simon Daenen, Norbert Vey, Khuda Dad Khan, Augustin Ferrant, Gail J. Roboz, Francis J. Giles, Stefan Faderl, Verena Karsten, Farhad Ravandi, Pierre W. Wijermans
Publikováno v:
Journal of Clinical Oncology, 25(1), 25-31. AMER SOC CLINICAL ONCOLOGY
Purpose Cloretazine (VNP40101M) is a sulfonylhydrazine alkylating agent with significant antileukemia activity. A multicenter phase II study of cloretazine was conducted in patients 60 years of age or older with previously untreated acute myeloid leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076d142e0511739b9fdff41c1492f9cd
https://pubmed.ncbi.nlm.nih.gov/17146103
https://pubmed.ncbi.nlm.nih.gov/17146103
Autor:
Robert A. Figlin, Myriam Bernal, Khuda Dad Khan, Robert G. Uzzo, Thomas E. Hutson, Michael B. Atkins, Robert W. Dubois, Ronald M. Bukowski, Ronald J. Halbert, Christopher G. Wood
Publikováno v:
Cancer. 107(10)
BACKGROUND. New developments in the treatment of patients with metastatic renal cell cancer (MRCC) have suggested a need to reevaluate the role of systemic therapies. The authors convened a panel of medical and urologic oncologists to rate the approp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d201e1f9340fe00ffee3aaecefee6b5
https://pubmed.ncbi.nlm.nih.gov/17048248
https://pubmed.ncbi.nlm.nih.gov/17048248