Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Khristofor Agassandian"'
Autor:
Khristofor Agassandian, Milan Patel, Marianna Agassandian, Karina E Steren, Kamal Rahmouni, Val C Sheffield, J Patrick Card
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93484 (2014)
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous inherited human disorder displaying a pleotropic phenotype. Many of the symptoms characterized in the human disease have been reproduced in animal models carrying deletions or knock-in mutati
Externí odkaz:
https://doaj.org/article/25fbfe19f7224e81908ac952865571ea
Autor:
Justin L. Grobe, Curt D. Sigmund, Khristofor Agassandian, Marianna Agassandian, Anthony P. Thompson, Xuebo Liu, Martin D. Cassell
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 312(6)
Direct intracerebroventricular injection of angiotensin II (ANG II) causes increases in blood pressure and salt and water intake, presumably mimicking an effect mediated by an endogenous mechanism. The subfornical organ (SFO) is a potential source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5305a18464dc53d7ba639767751ce166
https://pubmed.ncbi.nlm.nih.gov/28490451
https://pubmed.ncbi.nlm.nih.gov/28490451
Publikováno v:
Neuroscience. 227:247-259
C1 catecholamine neurons reside within the rostroventrolateral medulla (RVLM), an area that plays an integral role in blood pressure regulation through reticulospinal projections to sympathetic preganglionic neurons in the thoracic spinal cord. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23faf6a590d12ed17589cccdfbfa009b
https://doi.org/10.1016/j.neuroscience.2012.09.049
https://doi.org/10.1016/j.neuroscience.2012.09.049
Autor:
Asish K. Saha, Sergio Rodriguez-Cuenca, Krishna Chatterjee, Carlos Dieguez, Erik Schoenmakers, Khristofor Agassandian, Luis M. Varela, Sulay Tovar, Ricardo Lage, Rubén Nogueiras, Pablo B. Martínez de Morentin, Miguel López, Matej Orešič, Antonio Vidal-Puig, Kamal Rahmouni, Donald A. Morgan, Vidya Velagapudi, Christopher J. Lelliott, David Carling, Carmen R. González, Rosalía Gallego, María J. Vázquez
Publikováno v:
Nature Medicine
Nature medicine
López, M, Varela, L, Vázquez, M J, Rodríguez-Cuenca, S, González, C R, Velagapudi, V, Morgan, D A, Schoenmakers, E, Agassandian, K, Lage, R, Martínez de Morentin, P B, Tovar, S, Nogueiras, R, Carling, D, Lelliott, C, Gallego, R, Orešič, M, Chatterjee, K, Saha, A K, Rahmouni, K, Diéguez, C & Vidal-Puig, A 2010, ' Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance ', Nature Medicine, vol. 16, pp. 1001-1008 . https://doi.org/10.1038/nm.2207
Nature Medicine; Vol 16
Nature medicine
López, M, Varela, L, Vázquez, M J, Rodríguez-Cuenca, S, González, C R, Velagapudi, V, Morgan, D A, Schoenmakers, E, Agassandian, K, Lage, R, Martínez de Morentin, P B, Tovar, S, Nogueiras, R, Carling, D, Lelliott, C, Gallego, R, Orešič, M, Chatterjee, K, Saha, A K, Rahmouni, K, Diéguez, C & Vidal-Puig, A 2010, ' Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance ', Nature Medicine, vol. 16, pp. 1001-1008 . https://doi.org/10.1038/nm.2207
Nature Medicine; Vol 16
Thyroid hormones have widespread cellular effects; however it is unclear whether their effects on the central nervous system (CNS) contribute to global energy balance. Here we demonstrate that either whole-body hyperthyroidism or central administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de482d38144922a503f83019cb9057c
https://cris.vtt.fi/en/publications/a55a2dea-2d3a-4973-916a-865a7de445e6
https://cris.vtt.fi/en/publications/a55a2dea-2d3a-4973-916a-865a7de445e6
Autor:
Satoshi Morimoto, Curt D. Sigmund, Puspha Sinnayah, Koji Sakai, Robin L. Davisson, Khristofor Agassandian, Martin D. Cassell
Publikováno v:
Journal of Clinical Investigation. 117:1088-1095
The mechanism controlling cell-specific Ang II production in the brain remains unclear despite evidence supporting neuron-specific renin and glial- and neuronal-specific angiotensinogen (AGT) expression. We generated double-transgenic mice expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::367ce791f7ead9845386ca9208fd7225
https://doi.org/10.1172/jci31242
https://doi.org/10.1172/jci31242
Autor:
Khristofor Agassandian, Valéria Paula Sassoli Fazan, Naira V. Margaryan, Jeffrey D. Riley, Deidre Nitschke Dragon, William T. Talman
Publikováno v:
Cellular and Molecular Neurobiology. 23:463-478
1. We tested the hypothesis that arterial baroreceptor reflexes modulate cerebrovascular tone through a pathway that connects the cardiovascular nucleus tractus solitarii with parasympathetic preganglionic neurons in the pons. 2. Anesthetized rats we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35be530e4f03345806320ba05edeac89
https://doi.org/10.1023/a:1025059710382
https://doi.org/10.1023/a:1025059710382
Publikováno v:
The Journal of Comparative Neurology. 452:242-254
Peripheral or central interruption of the baroreflex or the parasympathetic innervation of cerebral vessels leads to similar changes in regulation of cerebral blood flow. Therefore, we sought to test the hypothesis that the cardiovascular nucleus tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ef357ac827654f84bc55966b89d2ed
https://doi.org/10.1002/cne.10372
https://doi.org/10.1002/cne.10372
Publikováno v:
Brain structurefunction. 220(5)
The expression of a vesicular glutamate transporter (VGLUT) suffices to assign a glutamatergic phenotype to neurons and other secretory cells. For example, intestinal L cells express VGLUT2 and secrete glutamate along with glucagon-like peptide 1 (GL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f7b00fc292bf2d58979f56156f4c32
https://pubmed.ncbi.nlm.nih.gov/25012114
https://pubmed.ncbi.nlm.nih.gov/25012114
Autor:
Charles Yeaman, Kevin Bugge, Khristofor Agassandian, Martin D. Cassell, Ruth E. Swiderski, Jean L. Ross
Publikováno v:
Fluids and Barriers of the CNS, Vol 9, Iss 1, p 22 (2012)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Background Hydrocephalus is a heterogeneous disorder with multiple etiologies that are not yet fully understood. Animal models have implicated dysfunctional cilia of the ependyma and choroid plexus in the development of the disorder. In this report,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c869369a5fde16b8655671a2c837623e
http://www.fluidsbarrierscns.com/content/9/1/22
http://www.fluidsbarrierscns.com/content/9/1/22
Autor:
Maria Luisa S. Sequeira Lopez, Di Xu, Giulianna R. Borges, Martin D. Cassell, R. Ariel Gomez, Curt D. Sigmund, Deborah R. Davis, Justin L. Grobe, Khristofor Agassandian
Publikováno v:
Physiological genomics. 43(6)
The renin-angiotensin system (RAS), known for its roles in cardiovascular, metabolic, and developmental regulation, is present in both the circulation and in many individual tissues throughout the body. Substantial evidence supports the existence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64d9128b31222eb3632f1e2db1db113
https://pubmed.ncbi.nlm.nih.gov/21189370
https://pubmed.ncbi.nlm.nih.gov/21189370