Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Khrishen Cunnusamy"'
Autor:
Jorge Franco, Parul Chaudhary, Nitin J. Karandikar, Ethan J. Baughman, Elliot M. Frohman, Khrishen Cunnusamy, Benjamin Greenberg, Sterling B. Ortega, Sushmita Sinha
Publikováno v:
Clinical immunology (Orlando, Fla.), vol 152, iss 1-2
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS). Although its etiology remains unknown, pathogenic T cells are thought to underlie MS immune pathology. We recently showed that MS patients harbor C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0742330b93292c430a881cab8a83c148
https://doi.org/10.1016/j.clim.2014.03.005
https://doi.org/10.1016/j.clim.2014.03.005
Publikováno v:
American Journal of Transplantation. 13:3076-3084
Th1 CD4+ cells are believed to be the primary mediators of corneal allograft rejection. However, rejection of fully allogeneic C57BL/6 corneal allografts soared from 50% to 90% in both interferon-gamma (IFN-γ)(-/-) and anti-IFN-γ-treated BALB/c mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec229fe43a507c05bbbf30e7fcbd04c2
https://doi.org/10.1111/ajt.12466
https://doi.org/10.1111/ajt.12466
Autor:
Walter Beebe, Robert N Hogan, Venkateswara Mootha, Charles B. Bowman, Xin Gong, Khrishen Cunnusamy
Purpose To describe 2 cases of congenital corneal endothelial edema resulting from novel de novo mutations. Methods Case A patient was a 15-month-old white child and case B patient was a 3-year-old Hispanic child presenting with bilateral cloudy corn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ce7fbeebe1d72a83852690eb0c8326
https://europepmc.org/articles/PMC4706791/
https://europepmc.org/articles/PMC4706791/
Publikováno v:
Pharmaceutical Patent Analyst. 1:193-206
Age-related macular degeneration (AMD) is the primary cause of blindness among the elderly worldwide. To date, no cure is available, and the available palliative treatments only showed limited efficacy in improving visual acuity. The etiology of AMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15156aa997504cecad35fb3d08a3216
https://doi.org/10.4155/ppa.12.12
https://doi.org/10.4155/ppa.12.12
Autor:
Nitin J. Karandikar, Jason Mendoza, Sterling B. Ortega, Khrishen Cunnusamy, Venkatesh P. Kashi, Andrew F. Tyler
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 191(1)
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS, and CD8 T cells are the predominant T cell population in MS lesions. Given that transfer of CNS-specific CD8 T cells results in an attenuated clinical demyelinating disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c132cd6149e6eb8d0d68cd8d3e7ce9
https://pubmed.ncbi.nlm.nih.gov/23733879
https://pubmed.ncbi.nlm.nih.gov/23733879
Autor:
Sushmita Sinha, Nitin J. Karandikar, Jason Mendoza, Elliot M. Frohman, Benjamin Greenberg, Khrishen Cunnusamy, Chris L. Ayers
Publikováno v:
Clinical immunology (Orlando, Fla.). 147(2)
Daily administration of FDA-approved glatiramer acetate (GA) has beneficial effects on clinical course of relapsing remitting multiple sclerosis (RRMS). Although mechanisms of GA-action have been widely investigated and partially understood, immediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade9356ea8602bbe227b9f4c450a6a3a
https://pubmed.ncbi.nlm.nih.gov/23578552
https://pubmed.ncbi.nlm.nih.gov/23578552
Autor:
Shusheng Wang, Khrishen Cunnusamy
Publikováno v:
Expert opinion on therapeutic patents. 23(2)
A pharmaceutical composition composed of several traditional Chinese medicines is claimed to treat age-related macular degeneration (AMD). This represents a novel and alternative therapeutic solution for wet AMD, with the potential advantage of treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f505bc8c35897e33f5c70aab490dcc6
https://pubmed.ncbi.nlm.nih.gov/23215532
https://pubmed.ncbi.nlm.nih.gov/23215532
Autor:
Sushmita Sinha, Khrishen Cunnusamy, Parul Chaudhary, Benjamin M Greenberg, Elliot M Frohman, Nitin J Karandikar
Publikováno v:
The Journal of Immunology. 196:49.8-49.8
Multiple sclerosis (MS) is the most common cause of neurological disability in young adults. Approximately 80% of MS patients initially present with the relapsing-remitting disease. Although studies suggest immune hyperactivity during relapse, role o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82746ff61610f2c5c2eb1d80a9b1a8e
https://doi.org/10.4049/jimmunol.196.supp.49.8
https://doi.org/10.4049/jimmunol.196.supp.49.8
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 186(12)
IL-17A is a proinflammatory cytokine that has received attention for its role in the pathogenesis of several autoimmune diseases. IL-17A has also been implicated in cardiac and renal allograft rejection. Accordingly, we hypothesized that depletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdda2dbb6601cf19f14a6c68b225c5c8
https://pubmed.ncbi.nlm.nih.gov/21551366
https://pubmed.ncbi.nlm.nih.gov/21551366
Publikováno v:
Plant physiology. 156(2)
Chlamydomonas reinhardtii possesses a CO2-concentrating mechanism (CCM) that allows the alga to grow at low CO2 concentrations. One common feature seen in photosynthetic organisms possessing a CCM is the tight packaging of Rubisco within the cell. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e54982b81d976c6c55c1990d07b441a
https://pubmed.ncbi.nlm.nih.gov/21527423
https://pubmed.ncbi.nlm.nih.gov/21527423