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Autor:
Ransohoff, D. F.1 ransohof@med.unc.edu, Khoury, M. J.2
Publikováno v:
European Journal of Clinical Investigation. Jan2010, Vol. 40 Issue 1, p64-68. 5p.
Autor:
Hutter, C. M., Mechanic, L. E., Chatterjee, N., Kraft, P., Gillanders, E. M., Abnet, C. C., Amos, C., Balshaw, D., Bickeböller, H., Bierut, L. J., Boffetta, P., Bondy, M., Chanock, S., Chen, H. -S., Cox, N., Vivo, I. D., Divi, R., Dupuis, J., Ellison, G., Fallin, M. D., Gauderman, W. J., Gillanders, E., Haiman, C., Hutter, C., Simonds, N. I., Iversen, E., Khoury, M. J., Marchand, L. L., McAllister, K., Mechanic, L., Peters, U., Prentice, R., Rebbeck, T., Reedy, J., Rothman, N., Schully, S., Seminara, D., Shaughnessy, D., Shete, S., Spiegelman, D., Stram, D. O., BALDWIN, THOMAS DONALD, Wang, M., WANG, WENPING, WEINBERG, CAREN HELENE, Winn, D. M., Witte, J. S.
Cancer risk is determined by a complex interplay of genetic and environmental factors. Genome-wide association studies (GWAS) have identified hundreds of common (minor allele frequency [MAF] > 0.05) and less common (0.01 < MAF < 0.05) genetic variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::782958fb1d819b537bc0e16c303de4a3
http://hdl.handle.net/11585/675639
http://hdl.handle.net/11585/675639
Publikováno v:
Scopus-Elsevier
Genet Med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::37584e7d4eff0642b2c23a9c2424dc48
http://olympias.lib.uoi.gr/jspui/handle/123456789/18086
http://olympias.lib.uoi.gr/jspui/handle/123456789/18086
Autor:
Ioannidis, J. P., Khoury, M. J.
Omics research poses acute challenges regarding how to enhance validation practices and eventually the utility of this rich information. Several strategies may be useful, including routine replication, public data and protocol availability, funding i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::9a51e5a67474de24cbc1f0e8af42a016
http://olympias.lib.uoi.gr/jspui/handle/123456789/20918
http://olympias.lib.uoi.gr/jspui/handle/123456789/20918
Recent emphasis on translational research (TR) is highlighting the role of epidemiology in translating scientific discoveries into population health impact. The authors present applications of epidemiology in TR through 4 phases designated T1-T4, ill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::6d72930754c57e30a4d4ed2a634bed90
http://olympias.lib.uoi.gr/jspui/handle/123456789/24499
http://olympias.lib.uoi.gr/jspui/handle/123456789/24499
Autor:
Lill, C. M., Schjeide, B. M., Roehr, J. T., Zauft, U., Allen, N. C., Zipp, F., McQueen, M. B., Kavvoura, F. K., Ioannidis, J. P., Khoury, M. J., Tanzi, R. E., Bertram, L.
Biol Psychiatry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::10e179fd3aa94264608eba83876a0757
http://olympias.lib.uoi.gr/jspui/handle/123456789/22749
http://olympias.lib.uoi.gr/jspui/handle/123456789/22749
Autor:
Janssens, A. C., Gonzalez-Zuloeta Ladd, A. M., Lopez-Leon, S., Ioannidis, J. P., Oostra, B. A., Khoury, M. J., van Duijn, C. M.
PURPOSE: Consortia of investigators currently compile sufficiently large sample sizes to investigate the effects of low-risk susceptibility genetic variants. It is not clear how the results obtained by consortia compare with those derived from meta-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::2fd9aeec2379eefbbf634814e884c1fa
http://olympias.lib.uoi.gr/jspui/handle/123456789/23907
http://olympias.lib.uoi.gr/jspui/handle/123456789/23907
Personal genome tests are now offered direct-to-consumer (DTC) via genetic variants identified by genome-wide association studies (GWAS) for common diseases. Tests report risk estimates (age-specific and lifetime) for various diseases based on genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::d20ad6b16fddbb0ecb4c7fb2dad8bc80
http://olympias.lib.uoi.gr/jspui/handle/123456789/18687
http://olympias.lib.uoi.gr/jspui/handle/123456789/18687
The authors evaluated whether there is an excess of statistically significant results in studies of genetic associations with Alzheimer's disease reflecting either between-study heterogeneity or bias. Among published articles on genetic associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10561::daf7dbda4fef5e54246451e90c34663c
http://olympias.lib.uoi.gr/jspui/handle/123456789/21792
http://olympias.lib.uoi.gr/jspui/handle/123456789/21792