Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Khosrowdad Salehi"'
Autor:
Juliane D. Glaeser, Xianchao Bao, Giselle Kaneda, Pablo Avalos, Phillip Behrens, Khosrowdad Salehi, Xiaoyu Da, Angel Chen, Chloe Castaneda, Pawel Nakielski, Wensen Jiang, Wafa Tawackoli, Dmitriy Sheyn
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Cranial bone loss presents a major clinical challenge and new regenerative approaches to address craniofacial reconstruction are in great demand. Induced pluripotent stem cell (iPSC) differentiation is a powerful tool to generate mesenchymal
Externí odkaz:
https://doaj.org/article/095f812c9d1949cfb068a40a2a992f3b
Autor:
Juliane D. Glaeser, Phillip Behrens, Tina Stefanovic, Khosrowdad Salehi, Angela Papalamprou, Wafa Tawackoli, Melodie F. Metzger, Samuel Eberlein, Trevor Nelson, Yasaman Arabi, Kevin Kim, Robert H. Baloh, Shiran Ben‐David, Doron Cohn‐Schwartz, Robert Ryu, Hyun W. Bae, Zulma Gazit, Dmitriy Sheyn
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 797-809 (2021)
Abstract Replacement of lost cranial bone (partly mesodermal and partly neural crest‐derived) is challenging and includes the use of nonviable allografts. To revitalize allografts, bone marrow‐derived mesenchymal stromal cells (mesoderm‐derived
Externí odkaz:
https://doaj.org/article/623fd8f367c6432984c32584341c5193
Autor:
Juliane D. Glaeser, Wafa Tawackoli, Derek G. Ju, Jae H. Yang, Linda EA Kanim, Khosrowdad Salehi, Victoria Yu, Evan Saidara, Jean‐Phillipe Vit, Zhanna Khnkoyan, Zachary NaPier, Laura S. Stone, Hyun W. Bae, Dmitriy Sheyn
Publikováno v:
JOR Spine, Vol 3, Iss 2, Pp n/a-n/a (2020)
Abstract Introduction Intervertebral disc (IVD) degeneration is often associated with low back pain and radiating leg pain. The purpose of this study is to develop a reproducible and standardized preclinical model of painful lumbar IVD degeneration b
Externí odkaz:
https://doaj.org/article/8a0ae43dace042aeab9d338ce0f2e886
Autor:
Juliane D. Glaeser, Derek Ju, Wafa Tawackoli, Jae H. Yang, Khosrowdad Salehi, Tina Stefanovic, Linda E. A. Kanim, Pablo Avalos, Giselle Kaneda, Stephen Stephan, Melodie F. Metzger, Hyun W. Bae, Dmitriy Sheyn
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9709 (2020)
Type 2 diabetes mellitus (T2DM) is associated with advanced glycation end product (AGE) enrichment and considered a risk factor for intervertebral disc (IVD) degeneration. We hypothesized that systemic AGE inhibition, achieved using pyridoxamine (PM)
Externí odkaz:
https://doaj.org/article/08842e18f8d641b19cf803c02ec753f6
Autor:
Wensen Jiang, Juliane D Glaeser, Giselle Kaneda, Julia Sheyn, Jacob T Wechsler, Stephen Stephan, Khosrowdad Salehi, Julie L. Chan, Wafa Tawackoli, Pablo Avalos, Christopher Johnson, Chloe Castaneda, Linda EA Kanim, Teerachat Tanasansomboon, Joshua Burda, Oksana Shelest, Haneen Yameen, Tiffany G Perry, Michael Kropf, Jason M Cuellar, Dror Seliktar, Hyun W Bae, Laura S Stone, Dmitriy Sheyn
Low back pain (LBP) is often associated with the degeneration of human intervertebral discs (IVDs). However, the pain-inducing mechanism in degenerating discs remains to be elucidated. Here, we identified a subtype of locally residing nucleus pulposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f631f2b138b55770090908c29ceb4292
https://doi.org/10.1101/2023.03.02.530506
https://doi.org/10.1101/2023.03.02.530506
Autor:
Zulma Gazit, Wafa Tawackoli, Robert H. Baloh, Melodie F. Metzger, Angela Papalamprou, Juliane D. Glaeser, Samuel Eberlein, Tina Stefanovic, Trevor J. Nelson, Doron Cohn‐Schwartz, Shiran Ben-David, Dmitriy Sheyn, Khosrowdad Salehi, Robert K. Ryu, Kevin J. Kim, Hyun W. Bae, Yasaman Arabi, Phillip H. Behrens
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 797-809 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 797-809 (2021)
Replacement of lost cranial bone (partly mesodermal and partly neural crest‐derived) is challenging and includes the use of nonviable allografts. To revitalize allografts, bone marrow‐derived mesenchymal stromal cells (mesoderm‐derived BM‐MSC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c283eaec32281621329a270fefe6036
https://doi.org/10.1002/sctm.20-0364
https://doi.org/10.1002/sctm.20-0364
Autor:
Juliane D Glaeser, Xianchao Bao, Giselle Kaneda, Pablo Avalos, Phillip Behrens, Khosrowdad Salehi, Xiaoyu Da, Angel Chen, Wensen Jiang, Chloe Castaneda, Wafa Tawackoli, Dmitriy Sheyn
Background Cranial bone loss presents a major clinical challenge and new regenerative approaches to address craniofacial reconstruction are in great demand. Induced pluripotent stem cell (iPSC) differentiation is a powerful tool to generate mesenchym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa9eda4493b5fdaad254985d51070ce6
https://doi.org/10.21203/rs.3.rs-1562664/v1
https://doi.org/10.21203/rs.3.rs-1562664/v1
Autor:
Linda E.A. Kanim, Michael A. Kropf, Juliane D. Glaeser, Tiffany G. Perry, Jason M. Cuellar, Dmitriy Sheyn, Zachary NaPier, Khosrowdad Salehi, Hyun W. Bae
Publikováno v:
Spine J
BACKGROUND CONTEXT Nonphysiological mechanical loading and inflammation are both critically involved in intervertebral disc (IVD) degeneration, which is characterized by an increase in cytokines and matrix metalloproteases (MMPs) in the nucleus pulpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94fe83c3b3f2fc0672747b0ad864738
https://doi.org/10.1016/j.spinee.2020.04.025
https://doi.org/10.1016/j.spinee.2020.04.025
Autor:
Linda E.A. Kanim, Zachary NaPier, Trevor J. Nelson, Melodie F. Metzger, Juliane D. Glaeser, Yasaman Arabi, Dmitriy Sheyn, Khosrowdad Salehi
Publikováno v:
Spine J
STUDY DESIGN: Experimental animal model. OBJECTIVE: The purpose of this study was to evaluate the hypothesis that insulin dependent diabetes mellitus (IDDM) will inhibit the formation of a solid bony union after spinal fusion surgery via an alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f3ee77678ce8660b7a7a5ad60920ce
https://doi.org/10.1016/j.spinee.2019.11.011
https://doi.org/10.1016/j.spinee.2019.11.011
Autor:
Jayme C.B. Koltsov, Linda E.A. Kanim, Khosrowdad Salehi, Hyun W. Bae, Brian A. Karamian, Zachary NaPier, Ivan Cheng, Timothy Thio, Juliane D. Glaeser, Jason R. Kang
Publikováno v:
The Spine Journal. 20:300-306
BACKGROUND CONTEXT Smoking is detrimental to obtaining a solid spinal fusion mass with previous studies demonstrating its association with pseudoarthrosis in patients undergoing spinal fusion. Varenicline is a pharmacologic adjunct used in smoking ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c997f2d2744c0bf5fd7fff98beddc56f
https://doi.org/10.1016/j.spinee.2019.07.015
https://doi.org/10.1016/j.spinee.2019.07.015