Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney

Autor: Khodus Gr, Hjalmar Brismar, Hans Blom, David Unnersjö-Jess, Jacopo M. Fontana, Anita Aperia

Publikováno v: The FASEB Journal

The central role of calcium signaling during development of early vertebrates is well documented, but little is known about its role in mammalian embryogenesis. We have used immunofluorescence and time-lapse calcium imaging of cultured explanted embr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5d2ccc6c7c20779275016c3a2e62e8f
https://doi.org/10.1096/fj.201802054r

Calcium oscillations triggered by cardiotonic steroids

Autor: Khodus Gr, Jacopo M. Fontana, Ievgeniia Burlaka, Anita Aperia, Hjalmar Brismar

Publikováno v: FEBS Journal. 280:5450-5455

Na(+), K(+)-ATPase (NKA) is well known for its function as an ion pump. Studies during the last decade have revealed an additional role for NKA as a signal transducer. In this brief review, we describe how cardiotonic steroids, which are highly speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e3aca905fc5a237a62549b31d3a23f
https://doi.org/10.1111/febs.12448

Effect of dDAVP on basolateral cell surface water permeability in the outer medullary collecting duct

Autor: Ivanova Ln, Khodus Gr, G. S. Baturina, Viatcheslav Nesterov, E. I. Solenov

Publikováno v: European Biophysics Journal. 32:614-619

We report a novel approach for assessing the volume of living cells which allows quantitative, high-resolution characterization of dynamic changes in cell volume while retaining the cell functionality. The aim of this study was to evaluate the short-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e13019b7ef7fa47919e4d86832d9c6
https://doi.org/10.1007/s00249-003-0308-9

Ouabain protects against adverse developmental programming of the kidney

Autor: Xiao Li Liu, Anita Aperia, Hjalmar Brismar, Markus Kruusmägi, Juan Li, Ann-Christine Eklöf, Khodus Gr, Padideh Kamali-Zare, Sergey Zelenin

Publikováno v: Nature Communications

The kidney is extraordinarily sensitive to adverse fetal programming. Malnutrition, the most common form of developmental challenge, retards the formation of functional units, the nephrons. The resulting low nephron endowment increases susceptibility

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950333bd4b84bd1f21ccb28bf429d6c1
https://pubmed.ncbi.nlm.nih.gov/20975704

Spontaneous calcium activity in metanephric mesenchymal cells regulates branching morphogenesis in the embryonic kidney.

Autor: Fontana JM; Department of Applied Physics, Science for Life Laboratory, Kungliga Tekniska Högskolan (KTH) Royal Institute of Technology, Solna, Sweden., Khodus GR; Department of Applied Physics, Science for Life Laboratory, Kungliga Tekniska Högskolan (KTH) Royal Institute of Technology, Solna, Sweden., Unnersjö-Jess D; Department of Applied Physics, Science for Life Laboratory, Kungliga Tekniska Högskolan (KTH) Royal Institute of Technology, Solna, Sweden., Blom H; Department of Applied Physics, Science for Life Laboratory, Kungliga Tekniska Högskolan (KTH) Royal Institute of Technology, Solna, Sweden., Aperia A; Department of Women's and Children's Health, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden., Brismar H; Department of Applied Physics, Science for Life Laboratory, Kungliga Tekniska Högskolan (KTH) Royal Institute of Technology, Solna, Sweden.; Department of Women's and Children's Health, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2019 Mar; Vol. 33 (3), pp. 4089-4096. Date of Electronic Publication: 2018 Nov 29.