Sigma-1 receptor modulation by fluvoxamine ameliorates valproic acid-induced autistic behavior in rats: Involvement of chronic ER stress modulation, enhanced autophagy and M1/M2 microglia polarization.

Autor: Mohamed AF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Governorate, Giza 11562, Egypt; Faculty of Pharmacy, King Salman International University (KSIU), South Sinai 46612, Egypt. Electronic address: ahmed.fathi@pharma.cu.edu.eg., El-Gammal MA; Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Horus University, New Damietta 34518, Egypt. Electronic address: melgamal@horus.edu.eg., El-Yamany MF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Governorate, Giza 11562, Egypt. Electronic address: mohammed.elyamany@pharma.cu.edu.eg., Khodeir AE; Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Horus University, New Damietta 34518, Egypt. Electronic address: akhodir@horus.edu.eg.

Publikováno v: Progress in neuro-psychopharmacology & biological psychiatry [Prog Neuropsychopharmacol Biol Psychiatry] 2024 Nov 05; Vol. 136, pp. 111192. Date of Electronic Publication: 2024 Nov 05.