Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Khodabukus A"'
Autor:
Alastair Khodabukus, Neel K. Prabhu, Taylor Roberts, Meghan Buldo, Amber Detwiler, Zachary D. Fralish, Megan E. Kondash, George A. Truskey, Timothy R. Koves, Nenad Bursac
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Dysferlin is a multi‐functional protein that regulates membrane resealing, calcium homeostasis, and lipid metabolism in skeletal muscle. Genetic loss of dysferlin results in limb girdle muscular dystrophy 2B/2R (LGMD2B/2R) and other dysfer
Externí odkaz:
https://doaj.org/article/6700577ad99f405e9fef15eac55bfc59
Autor:
Khodabukus, Alastair1 alastair.khodabukus@duke.edu, Prabhu, Neel K.1, Roberts, Taylor1, Buldo, Meghan1, Detwiler, Amber1, Fralish, Zachary D.1, Kondash, Megan E.1, Truskey, George A.1, Koves, Timothy R.2, Bursac, Nenad1 nbursac@duke.edu
Publikováno v:
Advanced Science. 8/21/2024, Vol. 11 Issue 31, p1-15. 15p.
Autor:
Broer, Torie, Tsintolas, Nick, Purkey, Karly, Hammond, Stewart, DeLuca, Sophia, Wu, Tianyu, Gupta, Ishika, Khodabukus, Alastair, Bursac, Nenad
Publikováno v:
In Acta Biomaterialia 15 October 2024 188:65-78
Autor:
David E. Lee, Lauren K. McKay, Akshay Bareja, Yongwu Li, Alastair Khodabukus, Nenad Bursac, Gregory A. Taylor, Gurpreet S. Baht, James P. White
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Lee et al. demonstrate the protein Meteorin-like can rejuvenate the body’s immune system to enhance muscle regeneration in old age – in part by inducing the death of pro-fibrotic mesenchymal progenitor cells within the muscle.
Externí odkaz:
https://doaj.org/article/8fcfebcc8c834ce3ab90df115f69407e
Autor:
Wang, Jason, Broer, Torie, Chavez, Taylor, Zhou, Chris J., Tran, Sabrina, Xiang, Yu, Khodabukus, Alastair, Diao, Yarui, Bursac, Nenad
Publikováno v:
In Biomaterials May 2022 284
Autor:
Christopher G Vann, Xin Zhang, Alastair Khodabukus, Melissa C. Orenduff, Yu-Hsiu Chen, David L. Corcoran, George A. Truskey, Nenad Bursac, Virginia B. Kraus
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Exercise affects the expression of microRNAs (miR/s) and muscle-derived extracellular vesicles (EVs). To evaluate sarcoplasmic and secreted miR expression in human skeletal muscle in response to exercise-mimetic contractile activity, we utilized a th
Externí odkaz:
https://doaj.org/article/01b3dc9dd88a468698e95c74c8051b9e
Autor:
Jason Wang, Chris J. Zhou, Alastair Khodabukus, Sabrina Tran, Sang-Oh Han, Aaron L. Carlson, Lauran Madden, Priya S. Kishnani, Dwight D. Koeberl, Nenad Bursac
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Wang et al. describe the development of a 3D in vitro model of human skeletal muscle that recapitulates the pathophysiology of Pompe disease. They further define a Pompe disease-specific transcriptional signature, confirm its presence in the Pompe my
Externí odkaz:
https://doaj.org/article/e7bed5b1c04b4acdbdebddf5309410f2
Autor:
Wang, Jason, Khodabukus, Alastair, Rao, Lingjun, Vandusen, Keith, Abutaleb, Nadia, Bursac, Nenad
Publikováno v:
In Biomaterials November 2019 221
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The neuromuscular junction (NMJ) is a specialized cholinergic synaptic interface between a motor neuron and a skeletal muscle fiber that translates presynaptic electrical impulses into motor function. NMJ formation and maintenance require tightly reg
Externí odkaz:
https://doaj.org/article/e4ac321d1ee3490eaacbf19a442604d1
Autor:
Khodabukus, Alastair, Madden, Lauran, Prabhu, Neel K., Koves, Timothy R., Jackman, Christopher P., Muoio, Deborah M., Bursac, Nenad
Publikováno v:
In Biomaterials April 2019 198:259-269