Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Khine S Shan"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 1973 (2024)
The dysregulation of the phosphatidylinositol-3-kinase (PI3K) pathway can lead to uncontrolled cellular growth and tumorigenesis. Targeting PI3K and its downstream substrates has been shown to be effective in preclinical studies and phase III trials
Externí odkaz:
https://doaj.org/article/98a59503699a411db4055808e3ec768b
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 624 (2024)
The mitogen-activated protein kinase (MAPK) pathway is essential for cellular proliferation, growth, and survival. Constitutive activation of this pathway by BRAF mutations can cause downstream activation of kinases, leading to uncontrolled cellular
Externí odkaz:
https://doaj.org/article/f260241771784933af208779435e387e
Autor:
Khine S. Shan, Shivani Dalal, Nyein Nyein Thaw Dar, Omani McLish, Matthew Salzberg, Brian A. Pico
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 849 (2024)
Fibroblast growth factor receptors (FGFRs) are a family of receptor tyrosine kinases that are involved in the regulation of cell proliferation, survival, and development. FGFR alterations including amplifications, fusions, rearrangements, and mutatio
Externí odkaz:
https://doaj.org/article/04887597346b4c40868dda6d03e10e17
Autor:
Elizabeth Rubin, Khine S. Shan, Shivani Dalal, Dieu Uyen Dao Vu, Adriana M. Milillo-Naraine, Delia Guaqueta, Alejandra Ergle
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1064 (2024)
Human epidermal growth factor receptor 2 (HER2) belongs to the ErbB family, a group of four transmembrane glycoproteins with tyrosine kinase activity, all structurally related to epidermal growth factor receptor (EGFR). These tyrosine kinases are inv
Externí odkaz:
https://doaj.org/article/fd480a78dffc40518800a402275d5041
Publikováno v:
Cureus
Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. We detail a 60-years-old gentleman who was otherwise healthy presented to the hospital due to acute encephalopathy. He was subsequently found to have parathyroid carcinoma as the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba62b07f0371facdb53303ebf5626c5
http://europepmc.org/articles/PMC7417119
http://europepmc.org/articles/PMC7417119
Publikováno v:
Cureus
Macrocytic anemia is usually associated with vitamin B12 or folate deficiency. However, folate deficiency was rarely reported as a cause of hemolytic anemia. We present a case of a young man with a history of alcohol abuse who initially presented wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134b17e7c67f38446b39f6e2dcf55f75
https://doi.org/10.7759/cureus.8570
https://doi.org/10.7759/cureus.8570
Autor:
Khine S Shan, Qian Zhang
Publikováno v:
Cureus
A 35-year-old lady with a history of possible tuberculosis infection 15 years ago presented to the clinic with the chief complaint of cough. Incidental chest CT showed a right paratracheal and medial right apical heterogeneous soft tissue mass with c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45520cd8e9de4d717f5b1edb977195e9
http://europepmc.org/articles/PMC7377013
http://europepmc.org/articles/PMC7377013
Publikováno v:
Cureus
Anabolic-androgenic steroids (AAS) abuse is common in competitive athletes in order to enhance athletic performances. However, AAS abuse is often associated with deleterious side effects including but not limited to cardiovascular diseases, depressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8eb850bb055bbe2d2af3d7581e019d3
https://doi.org/10.7759/cureus.8332
https://doi.org/10.7759/cureus.8332
Publikováno v:
Cureus
A 38-year-old gentleman with no significant past medical history but had recent COVID-19 exposure presented to the hospital with the chief complaints of fever, shortness of breath, and generalized myalgia. He was unfortunately found to be severe acut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687910da7df2b2eb858f60bcaba9ece3
https://doi.org/10.7759/cureus.8074
https://doi.org/10.7759/cureus.8074
Publikováno v:
Cureus
Giant cell arteritis (GCA) is an immune-mediated systemic inflammation of large-sized arteries that predominantly affects elderly women. It may be considered as one of the risk factors for acute coronary syndrome (ACS). Moreover, patients with GCA ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21138dd9a0ac750fc8413317cc3088dc
https://doi.org/10.7759/cureus.8077
https://doi.org/10.7759/cureus.8077