Liquid-like Oral Sustained-Release System Based on Acid-Sensitive in situ Hydrogel for Alleviate Gastrointestinal Side Effects of Indobufen.

Autor: Tang Y; The Second Outpatient Department, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, PR China., Sun P; Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Nanjing 210009, PR China., Khiing AHR; Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Nanjing 210009, PR China., Sha K; Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Nanjing 210009, PR China., Qi X; Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Nanjing 210009, PR China; Industrial Technology Innovation Platform, Zhejiang Center for Safety Study of Drug Substances, Hangzhou 310018, China. Electronic address: qixiaole523@cpu.edu.cn., Wu Z; Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Nanjing 210009, PR China. Electronic address: zhenghongwu66@cpu.edu.cn.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2023 Dec; Vol. 112 (12), pp. 3141-3153. Date of Electronic Publication: 2023 Jul 18.