Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Khew-Voon Chin"'
Autor:
Zeid J. Khitan, Khew‐Voon Chin, Komal Sodhi, Murad Kheetan, Ahlim Alsanani, Joseph I. Shapiro
Publikováno v:
Obesity (Silver Spring)
OBJECTIVES: The triad of obesity, high protein diet from animal sources and disturbed gut microbiota have been linked to poor clinical outcome in COVID-19 patients. In this report, we are exploring the effect of oxidative stress resulting from the Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea0db14b921e83bfe0367e31e317994
https://pubmed.ncbi.nlm.nih.gov/35048549
https://pubmed.ncbi.nlm.nih.gov/35048549
Autor:
Khew-Voon Chin, Qin Shao
Publikováno v:
Nutrition Research and Practice
The rapid rise in the incidence of obesity has emerged as one of the most pressing global public health issues in recent years. The underlying etiological causes of obesity, whether behavioral, environmental, genetic, or a combination of several of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855f7a79a360c20eade929881c63fc9c
http://europepmc.org/articles/PMC3133759
http://europepmc.org/articles/PMC3133759
Publikováno v:
Biochemical and Biophysical Research Communications. 391:1318-1323
The effects of cAMP in cell are predominantly mediated by the cAMP-dependent protein kinase (PKA), which is composed of two genetically distinct subunits, catalytic (C) and regulatory (R), forming a tetrameric holoenzyme R(2)C(2). The only known func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2605828c070ddbbde0536c85f14eb083
https://doi.org/10.1016/j.bbrc.2009.12.026
https://doi.org/10.1016/j.bbrc.2009.12.026
Autor:
Shalini Gupta, Amjad Shidyak, Deepak Malhotra, Sankaridrug M. Periyasamy, M. Bashar Kahaleh, Larisa Fedorova, Zijian Xie, Sleiman Smaili, Khew Voon Chin, Vanamala Raju, Anna P. Shapiro, Nasser El-Okdi, Jihad Elkareh, Joseph I. Shapiro
Publikováno v:
Journal of Applied Physiology. 105:30-36
We previously reported that cardiotonic steroids stimulate collagen synthesis by cardiac fibroblasts in a process that involves signaling through the Na-K-ATPase pathway (Elkareh et al. Hypertension 49: 215–224, 2007). In this study, we examined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c21bd1f0ed9eece2d0fa5e7d7917c7b
https://doi.org/10.1152/japplphysiol.00119.2008
https://doi.org/10.1152/japplphysiol.00119.2008
Publikováno v:
Cancer Research. 65:8049-8056
(−)-Epigallocatechin-3-gallate (EGCG), the principal polyphenol in green tea, has been shown to inhibit the growth of many cancer cell lines and to suppress the phosphorylation of epidermal growth factor receptor (EGFR). We observed similar effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54aff2e0b4de4d5cafde65192198387
https://doi.org/10.1158/0008-5472.can-05-0480
https://doi.org/10.1158/0008-5472.can-05-0480
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 555:3-19
The inhibition of carcinogenesis by tea and tea polyphenols has been demonstrated in different animal models by many investigators. The mechanisms of this inhibitory activity have also been investigated extensively, mostly in cell culture systems, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6b86d455c72da63473991b4d2252f0
https://doi.org/10.1016/j.mrfmmm.2004.06.040
https://doi.org/10.1016/j.mrfmmm.2004.06.040
Autor:
Ragini, Vittal, Zachariah E, Selvanayagam, Yi, Sun, Jungil, Hong, Fang, Liu, Khew-Voon, Chin, Chung S, Yang
Publikováno v:
Molecular Cancer Therapeutics. 3:1091-1099
Many studies suggest green tea is a cancer chemopreventive agent. This effect has been attributed to its major constituent (−)-epigallocatechin-3-gallate (EGCG). EGCG is also observed to have cytotoxic anticancer effects, especially when used in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ae58307255aad37928816b5384f3fd
https://doi.org/10.1158/1535-7163.1091.3.9
https://doi.org/10.1158/1535-7163.1091.3.9
Autor:
Jiangang (Jason) Liao, Tsunekazu Kita, Yick Fu Wong, Khew Voon Chin, Kazuya Kudoh, Albert W. Lin, Winnie Yeo, Sook Fan Yap, Tak Hong Cheung, Chung S. Yang, Joe Weichung Shih, Tony K.H. Chung, Zachariah E. Selvanayagam, Ragini Vittal, Yong Lin
Publikováno v:
Drug Development Research. 62:124-133
Expressed sequence tags and genome sequencing have virtually uncovered all the genes and transcripts in the human genome. Functional genomic analysis of these genes will undoubtedly reveal their physiological roles in cells in the near future. Couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b526d461e12e3429d95b8ccc8b60176f
https://doi.org/10.1002/ddr.10375
https://doi.org/10.1002/ddr.10375
Autor:
Weng Lang Yang, Elena Reitman, Mary Ellen Cvijic, Tsunekazu Kita, Roald Ravatn, Lisa Iacono, Michael Shin, David Vettori, Khew Voon Chin
Publikováno v:
Annals of the New York Academy of Sciences. 968:49-64
Mechanisms of cAMP signal transduction have been thoroughly investigated for more than 40 years. From the binding of hormonal ligands to their receptors on the outer surface of the plasma membrane to the cytoplasmic activation of effectors, the ensui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50591040ed1be75fed0b6acec06c0ea
https://doi.org/10.1111/j.1749-6632.2002.tb04326.x
https://doi.org/10.1111/j.1749-6632.2002.tb04326.x
Publikováno v:
Fertility and Sterility. 77:1214-1218
Objective: To examine the expression profiles of luteinized granulosa cells isolated from women with normal or diminished ovarian reserve undergoing in vitro fertilization. Design: Expression profiling by complementary DNA microarray analysis. Settin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a74db04d0b9c36bfca1137557c3e58
https://doi.org/10.1016/s0015-0282(02)03114-x
https://doi.org/10.1016/s0015-0282(02)03114-x