Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kheng Sze. Chan"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45836 (2012)
Under the fluctuating circumstances provided by the innate dynamics of microtubules and opposing tensions resulted from microtubule-associated motors, it is vital to ensure stable kinetochore-microtubule attachments for accurate segregation. However,
Externí odkaz:
https://doaj.org/article/02d150a3740f4983ba217505023c2c71
Autor:
Kheng Sze. Chan
Apoptosis or programmed cell death is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. Here I showed that when a cell is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2d416e0f543d3569ac24b5ea6243ee
https://doi.org/10.32657/10356/48044
https://doi.org/10.32657/10356/48044
Autor:
Hei Chan, Chi Hang Wong, Soak-Kuan Lai, Hoi-Yeung Li, Chin Yee Ho, Kheng-Sze Chan, Cheng-Gee Koh
Publikováno v:
Nature cell biology. 11(1)
The guanine nucleotide exchange factor for Ran, RCC1, dynamically binds chromatin. During apoptosis, caspase-mediated activation of Mst1 induces histone H2B phosphorylation, which immobilizes RCC1 on the chromatin, leading to a reduction in nuclear R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8940e497bf2082c2e1aa6ee09d8794e3
https://pubmed.ncbi.nlm.nih.gov/19122593
https://pubmed.ncbi.nlm.nih.gov/19122593
Publikováno v:
Cell Death & Disease
The strategy of clinically targeting cancerous cells at their most vulnerable state during mitosis has instigated numerous studies into the mitotic cell death (MCD) pathway. As the hallmark of cancer revolves around cell-cycle deregulation, it is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c3bfbd33a34b4026ac5a209e5a24c9
http://europepmc.org/articles/PMC3481136
http://europepmc.org/articles/PMC3481136
Survivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis
Publikováno v:
Cell Death & Disease
Apoptosis is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. Here we showed that when a cell is under apoptotic stress,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a96d3f799567f5ca18d5f1763e065b5
https://doi.org/10.1038/cddis.2010.34
https://doi.org/10.1038/cddis.2010.34
Autor:
Chi-Hang Wong, Hei Chan, Chin-Yee Ho, Soak-Kuan Lai, Kheng-Sze Chan, Cheng-Gee Koh, Hoi-Yeung Li
Publikováno v:
Nature Cell Biology. 11:226-226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c50285ba6938042ba96d6e8cddbf506
https://doi.org/10.1038/ncb0209-226
https://doi.org/10.1038/ncb0209-226