Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kheem S. Bisht"'
Autor:
David Gius, Andrew P. Feinberg, Jane B. Trepel, Sunmin Lee, Hengmi Cui, Wenqiang Yu, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Kheem S. Bisht, Phuongmai Nguyen, Lei Huang, Lunching Sun
Supplementary Figures 1-4, Methods and Materials from DNA Methyltransferase 1 and 3B Activate BAG-1 Expression via Recruitment of CTCFL/BORIS and Modulation of Promoter Histone Methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca86961361bd4c73125d9eabe134c62
https://doi.org/10.1158/0008-5472.22375622.v1
https://doi.org/10.1158/0008-5472.22375622.v1
Autor:
David Gius, Andrew P. Feinberg, Mitsuo Oshimura, Hiroyuki Kugoh, Richard S. Lee, Krish Patel, Lunching Sun, Kheem S. Bisht, Hengmi Cui, Phuongmai Nguyen
Supplementary Figures 1-6, Methods and Materials from CTCFL/BORIS Is a Methylation-Independent DNA-Binding Protein That Preferentially Binds to the Paternal H19 Differentially Methylated Region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906bbe12c1e35f9980a9252e540511f9
https://doi.org/10.1158/0008-5472.22375791.v1
https://doi.org/10.1158/0008-5472.22375791.v1
Autor:
David Gius, Andrew P. Feinberg, Jane B. Trepel, Sunmin Lee, Hengmi Cui, Wenqiang Yu, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Kheem S. Bisht, Phuongmai Nguyen, Lei Huang, Lunching Sun
In a previous genomic analysis, using somatic methyltransferase (DNMT) knockout cells, we showed that hypomethylation decreased the expression of as many genes as were observed to increase, suggesting a previously unknown mechanism for epigenetic reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813caa1a86837798300d46c06ce06de9
https://doi.org/10.1158/0008-5472.c.6497882
https://doi.org/10.1158/0008-5472.c.6497882
Publikováno v:
International Journal of Biological Sciences, Vol 4, Iss 5, Pp 291-299 (2008)
Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as diabetes and metabolic syndromes. Two gene families have been shown to play a role in the genetic regulation of longevity; t
Externí odkaz:
https://doaj.org/article/7a77212e33ef4528a0d7f6334e6ca910
Publikováno v:
Cancer Research. 76:3078-3087
Changes in polysome-bound mRNA (translatome) are correlated closely with changes in the proteome in cells. Therefore, to better understand the processes mediating the response of glioblastoma to ionizing radiation (IR), we used polysome profiling to
Autor:
Douglas R. Spitz, Nukhet Aykin-Burns, Hyun-Seok Kim, Chu-Xia Deng, Kheem S. Bisht, Athanassios Vassilopoulos, Kristi Muldoon-Jacobs, Krish Patel, Kjerstin M. Owens, Sarki A. Abdulkadir, Phuongmai Nguyen, Keshav K. Singh, David Gius, Seong Hoon Park, Özkan Özden, Jason E. Savage, Riet van der Meer, J. Daniel Pennington
Publikováno v:
Cancer Cell. 17:41-52
The sirtuin gene family (SIRT) is hypothesized to regulate the aging process and play a role in cellular repair. This work demonstrates that SIRT3(-/-) mouse embryonic fibroblasts (MEFs) exhibit abnormal mitochondrial physiology as well as increases
Autor:
Gil Bar-Sela, Hengmi Cui, David Gius, Lunching Sun, Kheem S. Bisht, Phuongmai Nguyen, Elise C. Kohn, Andrew P. Feinberg
Publikováno v:
Molecular and Cellular Biology. 28:6720-6729
Chromatin status is characterized in part by covalent posttranslational modifications of histones that regulate chromatin dynamics and direct gene expression. BORIS (brother of the regulator of imprinted sites) is an insulator DNA-binding protein tha
Autor:
David Gius, Jane B. Trepel, Lunching Sun, Andrew P. Feinberg, Phuongmai Nguyen, Lei Huang, Kheem S. Bisht, Wenqiang Yu, Sunmin Lee, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Hengmi Cui
Publikováno v:
Cancer Research. 68:2726-2735
In a previous genomic analysis, using somatic methyltransferase (DNMT) knockout cells, we showed that hypomethylation decreased the expression of as many genes as were observed to increase, suggesting a previously unknown mechanism for epigenetic reg
Autor:
Jaime Leclerc, Mark Mishra, Lunching Sun, Nukhet Aykin-Burns, Kheem S. Bisht, Phuongmai Nguyen, J. Daniel Pennington, Douglas R. Spitz, David Gius, Hyun-Seok Kim, Bong Hyun Ahn, Chu-Xia Deng, Kristi Muldoon Jacobs
Publikováno v:
International Journal of Biological Sciences
Cellular longevity is a complex process relevant to age-related diseases including but not limited to chronic illness such as diabetes and metabolic syndromes. Two gene families have been shown to play a role in the genetic regulation of longevity; t
Autor:
J. Daniel Pennington, Kheem S. Bisht, Weiling Zhao, Tony J. C. Wang, Gil Bar-Sela, C. Matthew Bradbury, Lei Huang, David Gius, Michael E. Robbins, Phuongmai Nguyen, Mark Mishra, Rania T. Awwad, Eric Y. Chuang, Lunching Sun, Zhijun Chen
Publikováno v:
Clinical Cancer Research. 12:3823-3830
Purpose: There is a growing awareness that radiation-induced normal tissue injury in late-responding organs, such as the brain, kidney, and lung, involves complex and dynamic responses between multiple cell types that not only lead to targeted cell d