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Autor:
Kathryn A. Bonham, John C. Cheronis, Matthew J. Duggan, Sharon D. Loy, Lisa G. Allen, Khe Thanh Nguyen, James K. Blodgett, Shad R. Eubanks, Eric T. Whalley
Publikováno v:
Journal of Medicinal Chemistry. 35:1563-1572
A systematic study on the dimerization of the bradykinin (BK) antagonist D-Arg0-Arg1-Pro2-Hyp3-Gly4-Phe5-Ser6-D-Phe 7-Leu8-Arg9 has been performed. The first part of this study involved compounds wherein dimerization was carried out by sequentially r