Novel management of methylene blue extravasation: A case report and review of literature

Autor: Rashid Saeed Khokhar, Mansoor Aqil, Tariq Al-Zahrani, Adnan Gelidan, Khayal Al Khayal

Publikováno v: Saudi Journal of Anaesthesia, Vol 9, Iss 2, Pp 211-213 (2015)

Methylene blue is a highly irritant drug and has been used intraoperatively. Its accidental extravasation can lead to tissue necrosis. In this report, a unique management is described, and the patient recovered without any morbidity.

Externí odkaz: https://doaj.org/article/02577dc8fdc24963be44fd73648bef94

Development of 2-oxindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells

Autor: Radwan El-Haggar, Wagdy M. Eldehna, Amal Alharbi, Mahmoud F. Abo-Ashour, Hatem A. Abdel-Aziz, Maha Abdulla, Sara T. Al-Rashood, Tarfah Al-Warhi, Rehan Ahmad, Khayal Al-Khayal, Rezk R. Ayyad

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 320-329 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record

Mitochondrial anti-apoptotic Bcl2 and BclxL proteins, are overexpressed in multiple tumour types, and has been involved in the progression and survival of malignant cells. Therefore, inhibition of such proteins has become a validated and attractive t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de578076ffdba99b77c28743ae9af6c3
https://doaj.org/article/ae0ff9bf7af7424389e31b9650cd019c

Short-term outcomes after self-expandable metal stent insertion for obstructing colon cancer: a retrospective cohort study

Autor: Ahmed Mohammed Al-Mazrou, Omar Al-Obeed, Thamer Abdullah Bin Traiki, Ahmad Mohammed Zubaidi, Majid A Almadi, Noura Alhassan, Sulaiman A. Al-Shammari, Khayal Al-Khayal

Publikováno v: Annals of Saudi Medicine
Annals of Saudi Medicine, Vol 40, Iss 5, Pp 403-407 (2020)

BACKGROUND: Self-expanding metal stents (SEMS) are used as a bridge to surgery for colon cancer patients as an alternative to emergency surgery. Currently, there is a paucity of literature from Saudi Arabia on the preoperative usage of SEMS. OBJECTIV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8409bd3e046e238a4c79bdc355e1fea
http://europepmc.org/articles/PMC7532057

Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling

Autor: Adil Haseeb, Rehan Ahmad, Mohammed Elwatidy, Yazeid Alhaidan, Maha-Hamadien Abdulla, Adila Salih El-Obeid, Mansoor-Ali Vaali-Mohammed, Khayal Al-Khayal, Omar Al-Obeed, Hamad Al Dosary, Sabine Matou-Nasri, Zeyad Alehaideb, James H. McKerrow

Publikováno v: Cancer Cell International, Vol 20, Iss 1, Pp 1-17 (2020)
Cancer Cell International

Background Colorectal carcinoma is one of the most deadly cancers that requests effective and safe chemotherapy. Evaluation of natural product-based anticancer drugs as adjuvant treatment with fewer side effects is largely unexplored research fields.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c004fc655ecb06a9e43720de13921c
http://link.springer.com/article/10.1186/s12935-020-01206-x

Isolated Perianal Endometrioma: A Case Report and Literature Review

Autor: Riyadh Hakami, Hassan Mohammad Aloraini, Norah Ibrahim Alturki, Mohammed Alswayyed, Khayal Al-Khayal, Reem A. Alharbi, Shahad AlMansour

Publikováno v: The American Journal of Case Reports

Patient: Female, 33-year-old Final Diagnosis: Endometriosis Symptoms: Perianal pain • swelling Medication: — Clinical Procedure: — Specialty: Surgery Objective: Unusual clinical course Background: Endometriosis, a common condition among women o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deaeffa9be14f32ed144acbff0a1c8d
https://doi.org/10.12659/ajcr.934745