Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Khatora S Opperman"'
Autor:
Natasha Friend, Jacqueline E Noll, Khatora S Opperman, Kimberley C Clark, Krzysztof M Mrozik, Kate Vandyke, Duncan R Hewett, Andrew C W Zannettino
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228408 (2020)
Multiple myeloma, a plasma cell malignancy, is a genetically heterogeneous disease and the genetic factors that contribute to its development and progression remain to be fully elucidated. The tumour suppressor gene GLIPR1 has previously been shown t
Externí odkaz:
https://doaj.org/article/7cb27827dcad42d981a5755b63258ea0
Autor:
Krzysztof M. Mrozik, Chee M. Cheong, Duncan R. Hewett, Jacqueline E. Noll, Khatora S. Opperman, Alaknanda Adwal, Darryl L. Russell, Orest W. Blaschuk, Kate Vandyke, Andrew C. W. Zannettino
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 6, Pp 339-353 (2020)
Abstract N‐cadherin is a homophilic cell‐cell adhesion molecule that plays a critical role in maintaining vascular stability and modulating endothelial barrier permeability. Pre‐clinical studies have shown that the N‐cadherin antagonist pepti
Externí odkaz:
https://doaj.org/article/c6826197d1b54a479b78471d9ab82b5d
Autor:
Kate Vandyke, Andrew C.W. Zannettino, Peter J. Psaltis, Jacqueline E. Noll, Khatora S. Opperman
Publikováno v:
Cancer and Metastasis Reviews. 40:273-284
Macrophages are a vital component of the tumour microenvironment and crucial mediators of tumour progression. In the last decade, significant strides have been made in understanding the crucial functional roles played by macrophages in the developmen
Autor:
David P. Sester, Jacqueline E. Noll, Andrew C. Perkins, Andy Wu, Anuj Sehgal, Jean-Pierre Levesque, Liza-Jane Raggatt, Cheyenne J. Sandrock, Katharine M. Irvine, David A. Hume, Heng O, Graham Magor, Susan M. Millard, Allison R. Pettit, Lena Batoon, Simranpreet Kaur, Andrew C.W. Zannettino, Kim M. Summers, Khatora S. Opperman
SummaryMouse hematopoietic tissues contain abundant and heterogeneous populations of tissue-resident macrophages attributed trophic functions in control of immunity, hematopoiesis and bone homeostasis. A systematic strategy to characterise macrophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff609bb43afe099c836054c06fa42e52
https://doi.org/10.1101/2021.04.28.441876
https://doi.org/10.1101/2021.04.28.441876
Autor:
Simranpreet Kaur, Andy Wu, Katharine M. Irvine, Anuj Sehgal, Jean-Pierre Levesque, Liza J. Raggatt, Graham Magor, Ostyn Heng, David P. Sester, Andrew C. Perkins, Lena Batoon, Andrew C.W. Zannettino, Kim M. Summers, Jacqueline E. Noll, Allison R. Pettit, David A. Hume, Susan M. Millard, Cheyenne J. Sandrock, Khatora S. Opperman
Publikováno v:
Cell reports. 37(8)
Mouse hematopoietic tissues contain abundant tissue-resident macrophages that support immunity, hematopoiesis, and bone homeostasis. A systematic strategy to characterize macrophage subsets in mouse bone marrow (BM), spleen, and lymph node unexpected
Autor:
Khatora S, Opperman, Kate, Vandyke, Peter J, Psaltis, Jacqueline E, Noll, Andrew C W, Zannettino
Publikováno v:
Cancer metastasis reviews. 40(1)
Macrophages are a vital component of the tumour microenvironment and crucial mediators of tumour progression. In the last decade, significant strides have been made in understanding the crucial functional roles played by macrophages in the developmen
Autor:
Roger S. Lasken, Tuan V. Nguyen, Babatunde O. Oyajobi, Ryan C. Chai, Weng Hua Khoo, Khatora S. Opperman, Guy Ledergor, Katie L. Owen, Christine Seeliger, Alexander Swarbrick, Peter I. Croucher, Dirk Hose, Duncan R. Hewett, Akira Nguyen, Ido Amit, Justine R. Clark, Nataša Kovačić, Michelle M. McDonald, Kim De Veirman, Alexander P. Corr, Assaf Weiner, Rachael L. Terry, Andrew C.W. Zannettino, Tri Giang Phan, Kate Vandyke, Anja Seckinger, Daniel L. Roden, Belinda S. Parker, Dana T. Aftab, Ya Xiao, Jessica A. Pettitt, Karin Vanderkerken, Mark Novotny, Sindhu T. Mohanty
The era of targeted therapies has seen significant improvements in depth of response, progression-free survival, and overall survival for patients with multiple myeloma. Despite these improvements in clinical outcome, patients inevitably relapse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef7864fc479002428772b21d5df78c9
https://hdl.handle.net/10453/134791
https://hdl.handle.net/10453/134791
Autor:
Khatora S. Opperman, Kate Vandyke, Elizabeth A. Coulter, Andreas Evdokiou, Krzysztof M. Mrozik, Kimberley C. Clark, N. Schwarz, Peter I. Croucher, Jacqueline E. Noll, Peter J. Psaltis, Duncan R. Hewett, Andrew C.W. Zannettino
Publikováno v:
Neoplasia (New York, N.Y.)
Multiple myeloma is a fatal plasma cell malignancy that is reliant on the bone marrow microenvironment. The bone marrow is comprised of numerous cells of mesenchymal and hemopoietic origin. Of these, macrophages have been implicated to play a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7705ca9dfdcd2126a0d18ad635f5a3
https://hdl.handle.net/11541.2/137627
https://hdl.handle.net/11541.2/137627
Autor:
Natalya Plakhova, Andrew C.W. Zannettino, Kate Vandyke, Krzysztof M. Mrozik, Davies Gareth, Daniel L. Worthley, Kimberley C. Clark, Siddhartha Mukherjee, Duncan R. Hewett, Vasilios Panagopoulos, Alanah L. Bradey, Khatora S. Opperman
Publikováno v:
Cancers, Vol 12, Iss 2149, p 2149 (2020)
Cancers
Volume 12
Issue 8
Cancers
Volume 12
Issue 8
In most instances, multiple myeloma (MM) plasma cells (PCs) are reliant on factors made by cells of the bone marrow (BM) stroma for their survival and growth. To date, the nature and cellular composition of the BM tumor microenvironment and the criti
Autor:
Jacqueline E. Noll, Natasha Friend, Krzysztof M. Mrozik, Kate Vandyke, Khatora S. Opperman, Kimberley C. Clark, Duncan R. Hewett, Andrew C.W. Zannettino
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0228408 (2020)
PLoS ONE, Vol 15, Iss 1, p e0228408 (2020)
Multiple myeloma, a plasma cell malignancy, is a genetically heterogeneous disease and the genetic factors that contribute to its development and progression remain to be fully elucidated. The tumour suppressor gene GLIPR1 has previously been shown t