Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Khatcher O. Margossian"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Coacervation is widely studied as potential drug delivery platform, but formation of coacervates at lower pH ranges, such as found in the gastrointestinal tract, remains challenging. Here, using theory and experimental methods, the authors demonstrat
Externí odkaz:
https://doaj.org/article/7208a194d9d4420b98adf6bbb914ad88
Publikováno v:
Nature communications. 13(1)
Traditionally, complex coacervation is regarded as a process whereby two oppositely charged polyelectrolytes self-assemble into spherical droplets. Here, we introduce the polyzwitterionic complex, “pZC”, formed by the liquid-liquid phase separati
Autor:
Marcel U. Brown, Hong‐Gyu Seong, Khatcher O. Margossian, Lauren Bishop, Thomas P. Russell, Murugappan Muthukumar, Todd Emrick
Publikováno v:
Macromolecular Rapid Communications. 43:2100678
Polymer zwitterions continue to emerge as useful materials for numerous applications, ranging from hydrophilic and antifouling coatings to electronic materials interfaces. While several polymer zwitterion compositions are now well established, intere
Autor:
Matthew Tirrell, Sarah L. Perry, Anna Tropnikova, Khatcher O. Margossian, Ziyuan Song, Dimitrios Priftis, Jianjun Cheng, Lorraine Leon
Publikováno v:
Angewandte Chemie. 127:11280-11284
Reported is the ability of α-helical polypeptides to self-assemble with oppositely-charged polypeptides to form liquid complexes while maintaining their α-helical secondary structure. Coupling the α-helical polypeptide to a neutral, hydrophilic po
Autor:
Dimitrios Priftis, Xiaoxing Xia, Jian Qin, Juan J. de Pablo, Lorraine Leon, Khatcher O. Margossian, Sarah L. Perry, Matthew Tirrell
Publikováno v:
Macromolecules. 47:3076-3085
Complex coacervation was achieved by combining poly(allylamine) (PAH) or branched poly(ethylenimine) (PEI) with poly(acrylic acid) (PAA) and poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA). We systematically investigated the effects of stoichiome
Autor:
Katie A. Black, Kyle Q. Hoffmann, Ryan A. Klein, Derek Wong, Jonathan K. Whitmer, Juan J. de Pablo, Sarah L. Perry, Khatcher O. Margossian, Dimitrios Priftis, Matthew Tirrell, Charles F. Pierce, Jian Qin, Matthew J. Kade, Lorraine Leon
Publikováno v:
Nature Communications
Polyelectrolyte complexes present new opportunities for self-assembled soft matter. Factors determining whether the phase of the complex is solid or liquid remain unclear. Ionic polypeptides enable examination of the effects of stereochemistry on com