Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Khashayar Vakili"'
Autor:
Allison F. O’Neill, Alanna J. Church, Angela Feraco, Jennifer Spidle, Catherine B. Wall, Heung Bae Kim, Scott Elisofon, Khashayar Vakili, Max Pimkin, Neekesh V. Dharia, Nathan R. Shelman, Antonio R. Perez-Atayde, Carlos Rodriguez-Galindo
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105147- (2024)
Summary: Background: Paediatric hepatocellular carcinomas (HCC) traditionally arise in the context of a normal structural and functional liver and carry a dismal prognosis. While chemotherapy is the frontline standard, there is emerging interest in t
Externí odkaz:
https://doaj.org/article/815517d7f0434bec859aea2d0054fc02
Autor:
Donna C. Koo, MD, P. Nina Scalise, MD, Jonathan M. Durgin, MD, Eliza J. Lee, MD, Khashayar Vakili, MD, Heung Bae Kim, MD
Publikováno v:
Journal of Vascular Surgery Cases and Innovative Techniques, Vol 10, Iss 2, Pp 101413- (2024)
Pediatric lower extremity arterial catheterization-related injuries can result in significant long-term morbidity. Revascularization is challenging due to concerns for long-term patency and growth accommodation with synthetic grafts. We describe a no
Externí odkaz:
https://doaj.org/article/fe2f7b4ba39e4c62bf3707dbc5b2b533
Autor:
Rosanna K Ma, Pei-Yin Tsai, Alaa R Farghli, Alexandria Shumway, Matt Kanke, John D Gordan, Taranjit S Gujral, Khashayar Vakili, Manabu Nukaya, Leila Noetzli, Sean Ronnekleiv-Kelly, Wendy Broom, Joeva Barrow, Praveen Sethupathy
Publikováno v:
PLoS Genetics, Vol 20, Iss 3, p e1011216 (2024)
Fibrolamellar carcinoma (FLC) is a rare liver cancer that disproportionately affects adolescents and young adults. Currently, no standard of care is available and there remains a dire need for new therapeutics. Most patients harbor the fusion oncogen
Externí odkaz:
https://doaj.org/article/19487cd4b6304631ba2145c57eb9603a
Autor:
Adam B. Francisco, Matt Kanke, Andrew P. Massa, Timothy A. Dinh, Ramja Sritharan, Khashayar Vakili, Nabeel Bardeesy, Praveen Sethupathy
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
Fibrolamellar carcinoma (FLC) is an aggressive liver cancer primarily afflicting adolescents and young adults. Most patients with FLC harbor a heterozygous deletion on chromosome 19 that leads to the oncogenic gene fusion, DNAJB1-PRKACA. There are cu
Externí odkaz:
https://doaj.org/article/968619f64d184558ae2e1afe7fceb663
Autor:
Stephanie S. Kim, Ina Kycia, Michael Karski, Rosanna K. Ma, Evan A. Bordt, Julian Kwan, Anju Karki, Elle Winter, Ranan G. Aktas, Yuxuan Wu, Andrew Emili, Daniel E. Bauer, Praveen Sethupathy, Khashayar Vakili
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Fibrolamellar carcinoma (FLC) is a primary liver cancer that most commonly arises in adolescents and young adults in a background of normal liver tissue and has a poor prognosis due to lack of effective chemotherapeutic agents. The DNAJB1-PRKACA gene
Externí odkaz:
https://doaj.org/article/932a91da3a8749ee88d4d191f4c126d6
Autor:
Ranan G. Aktas, Michael Karski, Biju Issac, Liang Sun, Shira Rockowitz, Piotr Sliz, Khashayar Vakili
Publikováno v:
Cells, Vol 11, Iss 23, p 3797 (2022)
Organoids have been used to investigate the three-dimensional (3D) organization and function of their respective organs. These self-organizing 3D structures offer a distinct advantage over traditional two-dimensional (2D) culture techniques by creati
Externí odkaz:
https://doaj.org/article/ed70f046de8e472bbe2ed0eec99217ec
Autor:
Kaly A. Mueller, Kelly E. Glajch, Megan N. Huizenga, Remi A. Wilson, Eric J. Granucci, Amanda M. Dios, Adelaide R. Tousley, Maria Iuliano, Elizabeth Weisman, Michael J. LaQuaglia, Marian DiFiglia, Kimberly Kegel-Gleason, Khashayar Vakili, Ghazaleh Sadri-Vakili
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The Hippo signaling pathway is involved in organ size regulation and tumor suppression. Although inhibition of Hippo leads to tumorigenesis, activation of Hippo may play a role in neurodegeneration. Specifically, activation of the upstream r
Externí odkaz:
https://doaj.org/article/cccd0dab16664adfba16dc950c90aec9
Autor:
Zahra Labib, Stephanie Kim, Diego Porras, James Lock, Deborah Stein, Michael Ferguson, Heung Bae Kim, Khashayar Vakili
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 34, Iss C, Pp 37-40 (2018)
Acute multi-visceral ischemia secondary to multi-vessel thrombosis is rare in the pediatric population and to our knowledge it has not been previously reported. We present a 3-year old boy with acute thrombosis of the celiac trunk, superior mesenteri
Externí odkaz:
https://doaj.org/article/2af3c8e5335d4b75bab29d46c7138a71
Autor:
Michael J. LaQuaglia, Heung Bae Kim, Francis Fynn-Thompson, Christopher Baird, Khashayar Vakili
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 30, Iss C, Pp 14-18 (2018)
Background: Pediatric liver tumors occasionally present with vascular invasion. Standard anatomic resections usually result in complete resection when tumor is intra-hepatic; however, direct tumor extension into the inferior vena cava (IVC) and right
Externí odkaz:
https://doaj.org/article/abe464f0c48a49c292f6eb1c095d8e2d
Autor:
Eleonore, Valencia, Khashayar, Vakili, Ravi R, Thiagarajan, Mary P, Mullen, Francis, Fynn-Thompson, Christopher B, Weldon, Melody G, Duvall
Publikováno v:
Pediatric Critical Care Medicine. 23:e440-e450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c0643657641dd63ce0b956c79edcbb
https://doi.org/10.1097/pcc.0000000000002994
https://doi.org/10.1097/pcc.0000000000002994