Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Khashayar Khoshmanesh"'
Autor:
Sara Baratchi, Habiba Danish, Chanly Chheang, Ying Zhou, Angela Huang, Austin Lai, Manijeh Khanmohammadi, Kylie M. Quinn, Khashayar Khoshmanesh, Karlheinz Peter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Neutrophil infiltration and subsequent extracellular trap formation (NETosis) is a contributing factor in sterile inflammation. Furthermore, neutrophil extracellular traps (NETs) are prothrombotic, as they provide a scaffold for platelets an
Externí odkaz:
https://doaj.org/article/191da29b631948689004a7cdf75eeaf8
Autor:
Tetiana Hourani, Alexis Perez-Gonzalez, Khashayar Khoshmanesh, Rodney Luwor, Adrian A. Achuthan, Sara Baratchi, Neil M. O’Brien-Simpson, Akram Al-Hourani
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Macrophages are heterogeneous innate immune cells that are functionally shaped by their surrounding microenvironment. Diverse macrophage populations have multifaceted differences related to their morphology, metabolism, expressed markers, an
Externí odkaz:
https://doaj.org/article/aabdd5ccbaab4a468773259c96fcc933
Autor:
Emily Sutterby, Chanly Chheang, Peter Thurgood, Khashayar Khoshmanesh, Sara Baratchi, Elena Pirogova
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Photobiomodulation (PBM) refers to the use of light to modulate cellular processes, and has demonstrated utility in improving wound healing outcomes, and reducing pain and inflammation. Despite the potential benefits of PBM, the precise mole
Externí odkaz:
https://doaj.org/article/b239a09327d0466ab2998b158743c2f7
Publikováno v:
View, Vol 3, Iss 2, Pp n/a-n/a (2022)
Abstract Skin is exposed to a variety of potential stressors and stimulators that may impact homeostasis, healing, tumor development, inflammation, and irritation. As such it is important to understand the impact that these stimuli have on skin healt
Externí odkaz:
https://doaj.org/article/f8f282d80bfd4a6ba3cc1f16de680f20
Autor:
Sergio Aguilera Suarez, Nadia Chandra Sekar, Ngan Nguyen, Austin Lai, Peter Thurgood, Ying Zhou, Scott Needham, Elena Pirogova, Khashayar Khoshmanesh, Sara Baratchi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Here, we describe a motorized cam-driven system for the cyclic stretch of aortic endothelial cells. Our modular design allows for generating customized spatiotemporal stretch profiles by varying the profile and size of 3D printed cam and follower ele
Externí odkaz:
https://doaj.org/article/98f0c96447d54577a1bb6102897a96b5
Publikováno v:
Advanced Intelligent Systems, Vol 3, Iss 7, Pp n/a-n/a (2021)
Biodevices are crucial for monitoring vital physiological signals, managing chronic health conditions, developing artificial organs for assisting people with disabilities, and conducting various clinical and surgical procedures. However, existing bio
Externí odkaz:
https://doaj.org/article/ffec8b99f28044c5a693779dd8fc6bd2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/066402d4f1934a4686d117d43e057207
Autor:
Michael E. Kurdzinski, Berrak Gol, Aaron Co Hee, Peter Thurgood, Jiu Yang Zhu, Phred Petersen, Arnan Mitchell, Khashayar Khoshmanesh
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditio
Externí odkaz:
https://doaj.org/article/81f8c0f6d1034825bd243d5b9158e489
Autor:
Francisco Tovar-Lopez, Peter Thurgood, Christopher Gilliam, Ngan Nguyen, Elena Pirogova, Khashayar Khoshmanesh, Sara Baratchi
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Arterial endothelium experience physical stress associated with blood flow and play a central role in maintaining vascular integrity and homeostasis in response to hemodynamic forces. Blood flow within vessels is generally laminar and streamlined. Ho
Externí odkaz:
https://doaj.org/article/068dfd8f63484c60bc38ad298bc9bd18
Autor:
Sara Baratchi, Peter Keov, William G. Darby, Austin Lai, Khashayar Khoshmanesh, Peter Thurgood, Parisa Vahidi, Karin Ejendal, Peter McIntyre
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
TRPV4 is a non-selective cation channel that tunes the function of different tissues including the vascular endothelium, lung, chondrocytes, and neurons. GSK1016790A is the selective and potent agonist of TRPV4 and a pharmacological tool that is used
Externí odkaz:
https://doaj.org/article/d32593cbbda246a08316fc463d02fa30