Výsledky vyhledávání - "Khanum Ridler"

Akademický článek

No association of COMT (Val158Met) genotype with brain structure differences between men and women.

Autor: Anna Barnes, Matti Isohanni, Jennifer H Barnett, Olli Pietiläinen, Juha Veijola, Jouko Miettunen, Tiina Paunio, Päivikki Tanskanen, Khanum Ridler, John Suckling, Edward T Bullmore, Graham K Murray, Peter B Jones

Publikováno v: PLoS ONE, Vol 7, Iss 3, p e33964 (2012)

We examined the effect of the catechol-O-methyltransferase (COMT) Val158Met polymorphism (rs4680), on brain structure in a subset (N = 82) of general population members of the Northern Finland 1966 Birth Cohort, selected through a randomization proce

Externí odkaz: https://doaj.org/article/84b05822ca7b42f99c36b031d8889d37

Zobrazit plný text záznamu

JOP517953_Supplementary_material – Supplemental material for Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET

Autor: Khanum Ridler, Gunn, Roger N, Searle, Graham E, Barletta, Julien, Passchier, Jan, Dixson, Luanna, Hallett, William A, Ashworth, Sharon, Gray, Frank A, Burgess, Clare, Poggesi, Italo, Bullman, Jonathan N, Emiliangelo Ratti, Laruelle, Marc A, Eugenii A Rabiner

Supplemental material, JOP517953_Supplementary_material for Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET by Khanum Ridler, Roger N Gunn, Graham E Searle, Julien Barletta, Jan Passchier, Luan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459c1bd363f4e355c5f595d21e724719

Zobrazit plný text záznamu

Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET

Autor: Jonathan Bullman, Italo Poggesi, Julien Barletta, Emiliangelo Ratti, Jan Passchier, Eugenii A. Rabiner, Sharon Ashworth, Frank A Gray, Roger N. Gunn, William A. Hallett, Khanum Ridler, Marc Laruelle, Luanna Dixson, Clare Burgess, Graham E. Searle

Publikováno v: Journal of Psychopharmacology. 28:244-253

GSK1144814 is a potent, insurmountable antagonist at human NK1 and NK3 receptors. Understanding the relationship between plasma pharmacokinetics and receptor occupancy in the human brain, was crucial for dose selection in future clinical studies. GSK

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c0a3e7304e3b29b8a59a55d8c4f808
https://doi.org/10.1177/0269881113517953

Zobrazit plný text záznamu

Positron emission tomography imaging of dopamine D2/3 receptors in the human cortex with [11C]FLB 457: Reproducibility studies

Autor: Rajesh Narendran, W. Gordon Frankle, Chi-Min Chen, Maureen A. May, N. Scott Mason, Khanum Ridler, Marc Laruelle, Chester A. Mathis, Eugenii A. Rabiner, Steve Kendro

Publikováno v: Synapse. 65:35-40

In a recent PET study, we demonstrated the ability to measure amphetamine-induced DA release in the human cortex with the relatively high affinity dopamine D2/3 radioligand [11C]FLB 457 (Narendran et al., [2009] Synapse 63:447–461). The aim of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f4e352167bcfacc8b3f9f9403616776
https://doi.org/10.1002/syn.20813

Zobrazit plný text záznamu

The brain structural disposition to social interaction

Autor: Päivikki Tanskanen, John Suckling, Maël Lebreton, Graham K. Murray, Peter B. Jones, Edward T. Bullmore, Anna Barnes, Khanum Ridler, Jouko Miettunen, Matti Isohanni, Juha Veijola, Leena Peltonen, Marjo-Riitta Järvelin

Publikováno v: European Journal of Neuroscience. 29:2247-2252

Social reward dependence (RD) in humans is a stable pattern of attitudes and behaviour hypothesized to represent a favourable disposition towards social relationships and attachment as a personality dimension. It has been theorized that this long-ter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44344b53923179ec1808624001f8705d
https://doi.org/10.1111/j.1460-9568.2009.06782.x

Zobrazit plný text záznamu

Plný text ve formátu HTML

Morphometric Brain Abnormalities in Schizophrenia in a Population-Based Sample: Relationship to Duration of Illness

Autor: Matti Isohanni, Marianne Haapea, Graham K. Murray, Päivikki Tanskanen, Edward T. Bullmore, Jouko Miettunen, Peter B. Jones, Juha Veijola, Erika Jääskeläinen, Khanum Ridler

Publikováno v: Schizophrenia Bulletin. 36:766-777

Biased recruitment and sample selection may cause variability in neuroimaging studies. Epidemiologically principled population-based magnetic resonance imaging (MRI) studies of schizophrenia are very rare. We gathered structural MRI data on 154 subje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e220c52c5d24c48957a0fd62e00ca36d
https://doi.org/10.1093/schbul/sbn141

Zobrazit plný text záznamu

Brain Imaging Correlates of Depressive Symptom Severity and Predictors of Symptom Improvement After Antidepressant Treatment

Autor: Khanum Ridler, Emilio Merlo-Pich, John Suckling, Edward T. Bullmore, Cynthia H.Y. Fu, Steve C.R. Williams, Chi-Hua Chen

Publikováno v: Biological Psychiatry. 62:407-414

Background It would be therapeutically useful to predict clinical response to antidepressant drugs. We evaluated structural magnetic resonance imaging (MRI) and functional MRI (fMRI) data as predictors of symptom change in people with depression. Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0b2fd390e19e4228555c15361b6ba6
https://doi.org/10.1016/j.biopsych.2006.09.018

Zobrazit plný text záznamu

Fronto-cerebellar systems are associated with infant motor and adult executive functions in healthy adults but not in schizophrenia

Autor: Jouko Miettunen, Graham K. Murray, Khanum Ridler, Marianne Haapea, Edward T. Bullmore, Peter B. Jones, John Suckling, Päivikki Tanskanen, Matti Isohanni, Juha Veijola, Xavier Chitnis

Publikováno v: Proceedings of the National Academy of Sciences. 103:15651-15656

Delineating longitudinal relationships between early developmental markers, adult cognitive function, and adult brain structure could clarify the pathogenesis of neurodevelopmental disorders such as schizophrenia. We aimed to identify brain structura

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8a16031417138b1679fe9a9452ab61
https://doi.org/10.1073/pnas.0602639103

Zobrazit plný text záznamu

Neuroanatomical Correlates of Memory Deficits in Tuberous Sclerosis Complex

Autor: P. J. De Vries, C. M. E. Stephenson, Edward T. Bullmore, John Suckling, Patrick Bolton, Khanum Ridler, N Higgins

Publikováno v: Cerebral Cortex. 17:261-271

Tuberous sclerosis complex (TSC) is a multisystem syndrome classically associated with the occurrence of focal brain dysplasias. We used structural magnetic resonance imaging to test for neuroradiological abnormalities in TSC (tubers, white matter le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe56d74ee3ed7c88c0f3e6d9fcc05458
https://doi.org/10.1093/cercor/bhj144

Zobrazit plný text záznamu

Standardized Whole Brain Mapping of Tubers and Subependymal Nodules in Tuberous Sclerosis Complex

Autor: Khanum Ridler, N Higgins, Patrick Bolton, John Suckling, Edward T. Bullmore

Publikováno v: Scopus-Elsevier

Tuberous sclerosis complex is associated with radiologically visible abnormalities of brain structure, principally tubers and subependymal nodules. We reviewed the literature on neuroimaging of tubers and subependymal nodules and found qualitative ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73380379a58cf02e01e3b88789efce0c
https://doi.org/10.1177/08830738040190090501

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání