Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

Autor: Bradbury, C. A.¹, Khanim, F. L.², Hayden, R.², Bunce, C. M.², White, D. A.¹, Drayson, M. T.³, Craddock, C.³, Turner, B. M.¹ b.m.turner@bham.ac.uk

Publikováno v: Leukemia (08876924). Oct2005, Vol. 19 Issue 10, p1751-1759. 9p. 5 Graphs.

Development of a nano-luciferase based assay to measure the binding of SARS-CoV-2 spike receptor binding domain to ACE-2.

Autor: Lima MA; Molecular & Structural Bioscience, School of Life Sciences, Keele University Staffordshire, ST5 5BG, United Kingdom., Skidmore M; Molecular & Structural Bioscience, School of Life Sciences, Keele University Staffordshire, ST5 5BG, United Kingdom., Khanim F; School of Biomedical Sciences, Institute of Clinical Sciences Medical School University of Birmingham, Birmingham, B15 2TT, United Kingdom., Richardson A; School of Pharmacy and Bioengineering, Keele University Staffordshire, ST5 5BG, United Kingdom. Electronic address: a.richardson1@keele.ac.uk.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jan 01; Vol. 534, pp. 485-490. Date of Electronic Publication: 2020 Nov 17.

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Interaction of toll-like receptors and ACE-2 with different variants of SARS-CoV-2: A computational analysis.

Autor: Zahmatkesh, Azadeh¹ a.zahmatkesh@rvsri.ac.ir, Salmasi, Elham², Gholizadeh, Reza³

Publikováno v: BioImpacts. Jul2024, Vol. 14 Issue 4, p1-12. 12p.

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma.

Autor: Bryant J; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK.; Joint first authors., Batis N; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK.; Joint first authors., Franke AC; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK., Clancey G; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK., Hartley M; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK., Ryan G; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK., Brooks J; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK., Southam AD; School of Biosciences, University of Birmingham, Birmingham, UK.; Phenome Centre Birmingham, University of Birmingham, Birmingham, UK., Barnes N; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.; School of Pharmacy, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Parish J; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Roberts S; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Khanim F; School of Biomedical Sciences, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK., Spruce R; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK.; Joint senior authors., Mehanna H; Institute of Head and Neck Studies and Education (InHANSE), University of Birmingham, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Joint senior authors.

Publikováno v: Oncotarget [Oncotarget] 2019 Aug 27; Vol. 10 (50), pp. 5229-5244. Date of Electronic Publication: 2019 Aug 27 (Print Publication: 2019).