Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Khanh Dao Duc"'
Autor:
Sandra Peña-Díaz, Joseph D. Chao, Celine Rens, Hasti Haghdadi, Xingji Zheng, Keegan Flanagan, Mary Ko, Tirosh Shapira, Adrian Richter, Danay Maestre-Batlle, Julio Ortiz Canseco, Maximiliano Gabriel Gutierrez, Khanh Dao Duc, Steven Pelech, Yossef Av-Gay
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110555- (2024)
Summary: Compounds targeting host control of infectious diseases provide an attractive alternative to antimicrobials. A phenotypic screen of a kinase library identified compounds targeting glycogen synthase kinase 3 as potent inhibitors of Mycobacter
Externí odkaz:
https://doaj.org/article/733a7b48c7c74ef1be5a2e2bc8a78728
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Conventional dimensionality reduction methods like Multidimensional Scaling (MDS) are sensitive to the presence of orthogonal outliers, leading to significant defects in the embedding. We introduce a robust MDS method, called DeCOr-MDS (Detection and
Externí odkaz:
https://doaj.org/article/cf0f0aa2441b471a94883a7577c297dd
Publikováno v:
AIMS Mathematics, Vol 7, Iss 1, Pp 986-999 (2022)
Cryogenic electron microscopy (cryo-EM) has become widely used for the past few years in structural biology, to collect single images of macromolecules "frozen in time". As this technique facilitates the identification of multiple conformational stat
Externí odkaz:
https://doaj.org/article/8ecf21c9691d4844a0df44dea01c2a14
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101605- (2022)
Summary: Ribosome profiling is a powerful technique which maps the distribution of ribosomes along mRNAs to analyze translation genome-wide. Ribosome density can be affected by multiple factors, such as changes to translation initiation or elongation
Externí odkaz:
https://doaj.org/article/7557e064d6eb45c8a9410f9e25758220
Publikováno v:
Molecules, Vol 25, Iss 18, p 4262 (2020)
The extent of ribosomal heterogeneity has caught increasing interest over the past few years, as recent studies have highlighted the presence of structural variations of the ribosome. More precisely, the heterogeneity of the ribosome covers multiple
Externí odkaz:
https://doaj.org/article/50479058aee0454987bbfd93c6342528
Autor:
Khanh Dao Duc, Yun S Song
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007620 (2018)
[This corrects the article DOI: 10.1371/journal.pgen.1007166.].
Externí odkaz:
https://doaj.org/article/eddb11ab81d947ce978bb5414a5cc718
Autor:
Khanh Dao Duc, Yun S Song
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007166 (2018)
Previous studies have shown that translation elongation is regulated by multiple factors, but the observed heterogeneity remains only partially explained. To dissect quantitatively the different determinants of elongation speed, we use probabilistic
Externí odkaz:
https://doaj.org/article/fe92e74a3e6a480ebbd197a9047abdde
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 3, p e1004137 (2015)
Neuronal excitability relies on inward sodium and outward potassium fluxes during action potentials. To prevent neuronal hyperexcitability, potassium ions have to be taken up quickly. However, the dynamics of the activity-dependent potassium fluxes a
Externí odkaz:
https://doaj.org/article/50435b791b864fba927b59538ec0e5cc
Autor:
Khanh Dao Duc, Chun-Yao Lee, Pierre Parutto, Dror Cohen, Menahem Segal, Nathalie Rouach, David Holcman
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124694 (2015)
Neuronal networks can generate complex patterns of activity that depend on membrane properties of individual neurons as well as on functional synapses. To decipher the impact of synaptic properties and connectivity on neuronal network behavior, we in
Externí odkaz:
https://doaj.org/article/bdf1c5e2c6a44b84abfc5fe4e6be3d73
Publikováno v:
AIMS Mathematics, Vol 7, Iss 1, Pp 986-999 (2022)
Cryogenic electron microscopy (cryo-EM) has become widely used for the past few years in structural biology, to collect single images of macromolecules "frozen in time". As this technique facilitates the identification of multiple conformational stat