Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Khang Hua"'
Autor:
Sara El-Sahli, Khang Hua, Andrew Sulaiman, Jason Chambers, Li Li, Eliya Farah, Sarah McGarry, Dan Liu, Peiyong Zheng, Seung-Hwan Lee, Jiefeng Cui, Marc Ekker, Marceline Côté, Tommy Alain, Xuguang Li, Vanessa M. D’Costa, Lisheng Wang, Suresh Gadde
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, accounting for the majority of breast cancer-related death. Due to the lack of specific therapeutic targets, chemotherapeutic agents (e.g., paclitaxel) rem
Externí odkaz:
https://doaj.org/article/01bd15f375e049938f736c0619b78c47
Publikováno v:
Brain Sciences, Vol 10, Iss 5, p 286 (2020)
Glial cell line-derived neurotrophic factor (GDNF) was initially described as important for dopaminergic neuronal survival and is involved in many other essential functions in the central nervous system. Characterization of GDNF phenotype in mammals
Externí odkaz:
https://doaj.org/article/87fe5c2e77094e47af4d9c24488a1c99
Publikováno v:
Biomedicines, Vol 8, Iss 1, p 1 (2019)
Neurotoxin exposure of zebrafish larvae has been used to mimic a Parkinson’s disease (PD) phenotype and to facilitate high-throughput drug screening. However, the vulnerability of zebrafish to various neurotoxins was shown to be variable. Here, we
Externí odkaz:
https://doaj.org/article/6ca6d8c4346c4e44aa300659165173cd
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Adult zebrafish have the ability to regenerate cells of the central nervous system. However, few neuronal regeneration studies in adult zebrafish addressed their ability to regenerate specific types of neurons following cell specific ablation. We sho
Autor:
Hannah A. Nicolas, Frédérique Tesson, Marie-Andrée Akimenko, Hailey Quigley, Joshua Ivare, Khang Hua
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 251(4)
Background Lamin A/C gene (LMNA) mutations frequently cause cardiac and/or skeletal muscle diseases called striated muscle laminopathies. We created a zebrafish muscular laminopathy model using CRISPR/Cas9 technology to target the zebrafish lmna gene
Autor:
Rida Ansari, Lior Appelbaum, W. Philip Bartel, Carla Denise Bonan, Caroline H. Brennan, Edward A. Burton, Michael J. Carvan III, Karl J. Clark, Rosane Souza Da Silva, Konstantin A. Demin, Flavia De Santis, Vincenzo Di Donato, Elena Dreosti, Marc Ekker, Amanda Facciol, Gert Flik, Robert T. Gerlai, Marnix Gorissen, Fabrizio Grieco, Su Guo, Amanda A. Heeren, Dennis M. Higgs, Ellen J. Hoffman, Kerstin Howe, Khang Hua, Arnim Jenett, Allan V. Kalueff, Konstantinos Kalyviotis, Justin W. Kenney, Anton M. Lakstygal, Han B. Lee, Emmanuel Marquez-Legorreta, Noam Miller, Rodsy Modhurima, Stephan C.F. Neuhauss, Lucas P.J.J. Noldus, William HJ. Norton, Periklis Pantazis, David M. Parichy, Marielle Piber, John H. Postlethwait, David Pritchett, Hanyu Qin, Jason Rihel, Domino K. Schlegel, Ethan K. Scott, Alexander Stankiewicz, S.J. Stednitz, Ruud A.J. Tegelenbosch, Javier Terriente, Steven Tran, Benjamin Tsang, Sachiko Tsuda, Ruud van den Bos, Victor S. Van Laar, Monica Ryff Moreira Roca Vianna, P. Washbourne, Svante Winberg, Jiale Xu, David Zada, Irina V. Zhdanova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2d8bf5edd950288cc2f43ee814830f
https://doi.org/10.1016/b978-0-12-817528-6.01002-0
https://doi.org/10.1016/b978-0-12-817528-6.01002-0
Publikováno v:
Brain Sciences
Volume 10
Issue 5
Brain Sciences, Vol 10, Iss 286, p 286 (2020)
Volume 10
Issue 5
Brain Sciences, Vol 10, Iss 286, p 286 (2020)
Glial cell line-derived neurotrophic factor (GDNF) was initially described as important for dopaminergic neuronal survival and is involved in many other essential functions in the central nervous system. Characterization of GDNF phenotype in mammals
Autor:
Khang Hua, Marc Ekker
Zebrafish have a remarkable ability to generate new neurons throughout life and to regenerate those neurons after injury or cell loss. These properties make zebrafish an attractive experimental system to study development and regeneration of dopamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0099352937d837340d9a4b4027a069d
https://doi.org/10.1016/b978-0-12-817528-6.00022-x
https://doi.org/10.1016/b978-0-12-817528-6.00022-x
Autor:
Chee Ern David Wong, Anwar Norazit, Simon Monis, Khang Hua, Vishal Saxena, Suzita Mohd Noor, Marc Ekker
Publikováno v:
Journal of neurochemistryREFERENCES. 156(4)
Glial cell line-derived neurotrophic factor (GDNF) has been reported to enhance dopaminergic neuron survival and differentiation in vitro and in vivo, although those results are still being debated. Glial cell line-derived neurotrophic factor (gdnf)