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Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.

Autor: Yun JH; Channing Division of Network Medicine and.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Khan MAW; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee., Ghosh A; Pulmonary Critical Care and Sleep Medicine, Upstate Medical University, Syracuse, New York., Hobbs BD; Channing Division of Network Medicine and.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Castaldi PJ; Channing Division of Network Medicine and.; Harvard Medical School, Boston, Massachusetts., Hersh CP; Channing Division of Network Medicine and.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Miller PG; Harvard Medical School, Boston, Massachusetts.; Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts., Cool CD; Division of Pathology, Department of Medicine, University of Colorado, Aurora, Colorado., Sciurba F; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Barwick L; Emmes, Frederick, Maryland., Limper AH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota., Flaherty K; Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, Michigan., Criner GJ; Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania., Brown K; Department of Medicine, National Jewish Health, Denver, Colorado., Wise R; Department of Medicine, Johns Hopkins Medicine, Baltimore, Maryland; and., Martinez F; Department of Medicine, Weill Cornell Medical College, New York, New York., Silverman EK; Channing Division of Network Medicine and.; Harvard Medical School, Boston, Massachusetts., DeMeo D; Channing Division of Network Medicine and.; Harvard Medical School, Boston, Massachusetts., Cho MH; Channing Division of Network Medicine and.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Bick AG; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2023 Dec 01; Vol. 208 (11), pp. 1196-1205.

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.

Autor: Hahn AW; Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Menk AV; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania., Rivadeneira DB; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania., Augustin RC; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Xu M; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Li J; Department of Bioinformatics and Computational Biology, Division of Basic Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas., Wu X; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Mishra AK; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Gide TN; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia., Quek C; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia., Zang Y; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania., Spencer CN; Parker Institute for Cancer Immunotherapy, San Francisco, California., Menzies AM; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia., Daniel CR; Department of Epidemiology, Division of Cancer Prevention and Population Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas., Hudgens CW; Department of Translational Molecular Pathology, Division of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Nowicki T; Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of California Los Angeles, Los Angeles, California.; Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California.; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, California., Haydu LE; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Khan MAW; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Gopalakrishnan V; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Burton EM; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Malke J; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Simon JM; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Bernatchez C; Department of Biologics Development, Division of Therapeutics Discovery, University of Texas MD Anderson Cancer Center, Houston, Texas., Putluri N; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Woodman SE; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Vashisht Gopal YN; Department of Melanoma Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Guerrieri R; Department of Melanoma Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Fischer GM; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Wang J; Department of Biostatistics, Division of Biosciences, University of Texas MD Anderson Cancer Center, Houston, Texas., Wani KM; Department of Translational Molecular Pathology, Division of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Thompson JF; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia., Lee JE; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Hwu P; Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa Bay, Florida., Ajami N; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Gershenwald JE; Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, California., Long GV; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia., Scolyer RA; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.; Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital and NSW Health Pathology, Sydney, New South Wales, Australia., Tetzlaff MT; Division of Dermatopathology, Department of Pathology, University of California San Francisco, San Francisco, California., Lazar AJ; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Translational Molecular Pathology, Division of Pathology and Laboratory Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Schadendorf D; Department of Dermatology, Venereology, and Allergology, University Hospital Essen and German Cancer Consortium, Partner site Essen, Germany., Wargo JA; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Surgical Oncology, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas., Kirkwood JM; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., DeBerardinis RJ; Children's Medical Research Institute and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas., Liang H; Department of Bioinformatics and Computational Biology, Division of Basic Sciences, University of Texas MD Anderson Cancer Center, Houston, Texas., Futreal A; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Zhang J; Department of Genomic Medicine, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Wilmott JS; Melanoma Institute of Australia, The University of Sydney, Sydney, New South Wales, Australia., Peng W; Department of Biology and Biochemistry, University of Houston, Houston, Texas., Davies MA; Department of Melanoma Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas., Delgoffe GM; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania., Najjar YG; Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., McQuade JL; Department of Melanoma Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Jan 04; Vol. 29 (1), pp. 154-164.