Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Khamlichi MD"'
1
Akademický článek
Outcomes of single brain metastasis treated with gamma knife stereotaxic radiosurgery(GKSR). Our experience on 103 cases
Autor: Nourou Dine Adeniran Bankole, MD, Adyl Melhaoui, MD, Yasser Arkha, MD, Afaf Semmar, MD, Khalid Bouyakhlef, PhD, Mohamed Jiddane, MD, Abdeslam El Khamlichi, MD
Publikováno v: IBRO Neuroscience Reports, Vol 14, Iss , Pp 138-145 (2023)
Background: Brain metastases (BM) occur in the natural course of malignant tumors in 18–40% of cases. Their management has changed considerably over the past decade thanks to the advent of Gamma knife Stereotactic Radiosurgery (GKSR). Objective: We
Externí odkaz: https://doaj.org/article/295f73867e46427b9749bbcf2b548b39
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2
Akademický článek
Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
Autor: McGowan DC; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium. Electronic address: dmcgowan@its.jnj.com., Herschke F; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Khamlichi MD; Villapharma Research, Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, Km. 2,5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Rosauro ML; Villapharma Research, Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, Km. 2,5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Benedicto SMP; Villapharma Research, Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, Km. 2,5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Pauwels F; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Stoops B; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Pande V; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Scholliers A; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Van Schoubroeck B; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Mostmans W; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Van Dijck K; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Thoné T; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Horton H; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Fanning G; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Jonckers THM; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium., Raboisson P; Janssen Infectious Diseases, Turnhoutseweg 30, 2340 Beerse, Belgium.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Oct 15; Vol. 28 (19), pp. 3216-3221. Date of Electronic Publication: 2018 Aug 16.
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3
Akademický článek
Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.
Autor: Pieters S; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium. Electronic address: spieters@its.jnj.com., McGowan D; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Herschke F; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Pauwels F; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Stoops B; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Last S; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Embrechts W; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Scholliers A; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Mostmans W; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Van Dijck K; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Van Schoubroeck B; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Thoné T; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., De Pooter D; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Fanning G; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Rosauro ML; Villapharma Research S.L., Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, km. 2.5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Khamlichi MD; Villapharma Research S.L., Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, km. 2.5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Houpis I; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Arnoult E; Janssen Research & Development L.L.C., 1400 McKean Rd, Spring House, PA 19454, United States., Jonckers THM; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium., Raboisson P; Janssen Infectious Diseases Diagnostics BVBA, Turnhoutseweg 30, 2340 Beerse, Belgium.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2018 Feb 15; Vol. 28 (4), pp. 711-719. Date of Electronic Publication: 2018 Jan 16.
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4
Akademický článek
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.
Autor: McGowan DC; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Herschke F; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Pauwels F; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Stoops B; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Smyej I; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Last S; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Pieters S; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Embrechts W; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Khamlichi MD; Villapharma Research S.L. , Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, Km. 2.5-Av. Azul, 30320 Fuente Álamo de Murcia, Murcia, Spain., Thoné T; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Van Schoubroeck B; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Mostmans W; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Wuyts D; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Verstappen D; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Scholliers A; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., De Pooter D; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Dhuyvetter D; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Borghys H; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Tuefferd M; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Arnoult E; Janssen Research & Development L.L.C. , 1400 McKean Road, Spring House, Pennsylvania 19454, United States., Hong J; Alios Biopharma, Inc. , 260 East Grand Avenue, South San Francisco, California 94080, United States., Fanning G; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Bollekens J; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Urmaliya V; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Teisman A; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Horton H; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Jonckers THM; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium., Raboisson P; Janssen Pharmaceutica , N. V. Turnhoutseweg 30, 2340 Beerse, Belgium.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Jul 27; Vol. 60 (14), pp. 6137-6151. Date of Electronic Publication: 2017 Jul 14.
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5
Akademický článek
Synthesis and evaluation of novel HCV replication inhibitors.
Autor: McGowan DC; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium. dmcgowan@its.jnj.com., Khamlichi MD; Villapharma Research, Parque Tecnológico de Fuente Álamo, Ctra. El Estrecho-Lobosillo, Km. 2,5- Av. Azul, 30320, Fuente Álamo de Murcia, Murcia, Spain., De Groot A; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium., Pauwels F; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium., Delouvroy F; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium., Van Emelen K; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium., Simmen K; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium., Raboisson P; Janssen Infectious Diseases BVBA, Turnhoutseweg 30, 2340, Beerse, Belgium.
Publikováno v: Molecular diversity [Mol Divers] 2017 May; Vol. 21 (2), pp. 475-481. Date of Electronic Publication: 2017 Mar 14.
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6
Akademický článek
Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.
Autor: McGowan D; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Herschke F; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Pauwels F; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Stoops B; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Last S; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Pieters S; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Scholliers A; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Thoné T; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Van Schoubroeck B; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., De Pooter D; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Mostmans W; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Khamlichi MD; Villapharma Research S.L. , Parque Tecnológico de Fuente Álamo. Ctra. El Estrecho-Lobosillo, Km. 2.5, Av. Azul 30320 Fuente Álamo de Murcia, Murcia, Spain., Embrechts W; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Dhuyvetter D; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Smyej I; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Arnoult E; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Demin S; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Borghys H; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Fanning G; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Vlach J; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium., Raboisson P; Janssen Infectious Diseases Diagnostics BVBA , Turnhoutseweg 30, 2340 Beerse, Belgium.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2016 Sep 08; Vol. 59 (17), pp. 7936-49. Date of Electronic Publication: 2016 Aug 23.
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7
Akademický článek
New Bioactive Semisynthetic Derivatives of 31-Norlanostenol and Obtusifoliol from Euphorbia officinarum.
Autor: Bailen M, Khamlichi MD, Benharref A, Martinez-Diaz RA, Gonzalez-Coloma A
Publikováno v: Natural product communications [Nat Prod Commun] 2016 Jun; Vol. 11 (6), pp. 733-8.
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8
Akademický článek
An insight on medicinal attributes of pyrimidine scaffold: An updated review.
Autor: Vyas, Akshun1 (AUTHOR), Sahu, Bhaskar1 (AUTHOR), Pathania, Shelly1 (AUTHOR), Nandi, Nilay Kumar1 (AUTHOR), Chauhan, Gaurav2 (AUTHOR), Asati, Vivek1 (AUTHOR) vivek.asati@isfcp.org, Kumar, Bhupinder1 (AUTHOR) bhupinderkumar25@gmail.com
Publikováno v: Journal of Heterocyclic Chemistry. Jul2023, Vol. 60 Issue 7, p1081-1121. 41p.
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