Výsledky vyhledávání - "Khalilah G. Reddie"

In vivofluorescence imaging of biomaterial-associated inflammation and infection in a minimally invasive manner

Autor: Shalu Suri, Khalilah G. Reddie, Niren Murthy, Shivaram Selvam, Andrés J. García, Susan M. Lehman, Santanu Maity

Publikováno v: Journal of Biomedical Materials Research Part A. 103:76-83

Implant-associated inflammation and bacterial infection severely limit the functional performance of medical devices and are a major cause of implant failure. Therefore, it is crucial to develop methodologies to monitor/image implant-associated asept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8a7465129e7431ccde15f91f9a14f64
https://doi.org/10.1002/jbm.a.35162

Zobrazit plný text záznamu

RegB Kinase Activity Is Repressed by Oxidative Formation of Cysteine Sulfenic Acid

Autor: Jiang Wu, Carl E. Bauer, Loubna A. Hammad, Zhuo Cheng, Jonathan A. Karty, Kate S. Carroll, Khalilah G. Reddie

Publikováno v: Journal of Biological Chemistry. 288:4755-4762

RegB/RegA comprise a global redox-sensing signal transduction system utilized by a wide range of proteobacteria to sense environmental changes in oxygen tension. The conserved cysteine 265 in the sensor kinase RegB was previously reported to form an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01623fad68f96927abc89a742aabffe2
https://doi.org/10.1074/jbc.m112.413492

Zobrazit plný text záznamu

Activity of the tetrapyrrole regulator CrtJ is controlled by oxidation of a redox active cysteine located in the DNA binding domain

Autor: Kate S. Carroll, Loubna A. Hammad, Aaron T. Setterdahl, Zhuo Cheng, Carl E. Bauer, Khalilah G. Reddie, Jonathan A. Karty, Jiang Wu

Publikováno v: Molecular Microbiology. 85:734-746

CrtJ from Rhodobacter capsulatus is a regulator of genes involved in the biosynthesis of haem, bacteriochlorophyll, carotenoids as well as structural proteins of the light harvesting-II complex. Fluorescence anisotropy-based DNA-binding analysis demo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89380a31a2d4c688b69574271c360cf2
https://doi.org/10.1111/j.1365-2958.2012.08135.x

Zobrazit plný text záznamu

Fluorescent Coumarin Thiols Measure Biological Redox Couples

Autor: Melissa L. Kemp, William H. Humphries, Khalilah G. Reddie, Christine K. Payne, Niren Murthy, Charlo P. Bain

Publikováno v: Organic Letters. 14:680-683

In this report we present a new chemical probe, 3-HTC, that can reversibly and ratiometrically measure the thiol-disulfide equilibrium of biological systems. 3-HTC is composed of a coumarin that has a thiolate directly conjugated to its extended arom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdaf8b76a58f5dfe2f81b4a7efc46f11
https://doi.org/10.1021/ol203105c

Zobrazit plný text záznamu

Mining the Thiol Proteome for Sulfenic Acid Modifications Reveals New Targets for Oxidation in Cells

Autor: Stephen E. Leonard, Kate S. Carroll, Khalilah G. Reddie

Publikováno v: ACS Chemical Biology. 4:783-799

Oxidation of cysteine to sulfenic acid has emerged as a biologically relevant post-translational modification with particular importance in redox- mediated signal transduction; however, the identity of modified proteins remains largely unknown. We re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba91fc01b4039961ea771520e70ed88
https://doi.org/10.1021/cb900105q

Zobrazit plný text záznamu

Inhibition of Kinesin Motor Proteins by Adociasulfate-2

Autor: Donald R. Roberts, Timothy M. Dore, Khalilah G. Reddie

Publikováno v: Journal of Medicinal Chemistry. 49:4857-4860

Kinesin motor proteins are involved in cell division and intracellular transport of vesicles and organelles, and as such, they play a role in neurological disease, cancer, and developmental disorders. Inhibitors of kinesin would be valuable as probes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cebfa1730868e8cc5892d6eeab90b8
https://doi.org/10.1021/jm060115z

Zobrazit plný text záznamu

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5

Autor: Robin M. Shaw, Lian Zhang, Laurie K. Svoboda, Sharlene M. Day, Eileen D. Vesely, Jeffrey R. Martens, Khalilah G. Reddie, Sarah M. Schumacher, Kate S. Carroll, Elizabeth S. Williams, Justus M.B. Anumonwo, Ryan P. O'Connell

Publikováno v: Circulation research. 111(7)

Rationale: Kv1.5 (KCNA5) is expressed in the heart, where it underlies the I Kur current that controls atrial repolarization, and in the pulmonary vasculature, where it regulates vessel contractility in response to changes in oxygen tension. Atrial f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b186df4f730c5ab28dde80bcab5073f
https://pubmed.ncbi.nlm.nih.gov/22843785

Zobrazit plný text záznamu

Substituent effects on the sensitivity of a quinoline photoremovable protecting group to one- and two-photon excitation

Autor: Hunter C. Wilson, M. Jarrett Davis, Yue Zhu, Khalilah G. Reddie, Christopher H. Kragor, Timothy M. Dore

Publikováno v: The Journal of organic chemistry. 74(4)

Photoremovable protecting groups that can reveal biologically important functional groups through one- and two-photon excitation (1PE and 2PE, respectively) have promise in regulating physiological function in a temporally and spatially restricted ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486c75be027e99c4b2d8729a36cd8e8d
https://pubmed.ncbi.nlm.nih.gov/19140722

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání