Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Khalil Saadeh"'
Publikováno v:
Education Sciences, Vol 13, Iss 10, p 1012 (2023)
University of Surrey’s School of Veterinary Medicine introduced an assessment called On The Spot Presentation-based Assessment (OTSPA) into the 3rd and 4th year of a 5-year veterinary degree programme. The OTSPA is designed as a low-weightage summa
Externí odkaz:
https://doaj.org/article/c7be516a35d44a5dbb3c9b597520b8de
Autor:
Antoine Premont, Khalil Saadeh, Charlotte Edling, Rebecca Lewis, Celia M. Marr, Kamalan Jeevaratnam
Publikováno v:
Physiological Reports, Vol 10, Iss 14, Pp n/a-n/a (2022)
Abstract Understanding cardiomyocyte ion channel expression is crucial to understanding normal cardiac electrophysiology and underlying mechanisms of cardiac pathologies particularly arrhythmias. Hitherto, equine cardiac ion channel expression has ra
Externí odkaz:
https://doaj.org/article/73a8f0b30a024508b727454840a30746
Transcriptional profiles of genes related to electrophysiological function in Scn5a+/− murine hearts
Autor:
Michael Takla, Charlotte E. Edling, Kevin Zhang, Khalil Saadeh, Gary Tse, Samantha C. Salvage, Christopher L.‐H. Huang, Kamalan Jeevaratnam
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Abstract The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initiation and propagation in both atria and ventricles predisposes organis
Externí odkaz:
https://doaj.org/article/edef003b381440f3af65dbd7393d25d6
Autor:
Khalil Saadeh, Karan R. Chadda, Shiraz Ahmad, Haseeb Valli, Nakulan Nanthakumar, Ibrahim T. Fazmin, Charlotte E. Edling, Christopher L.-H. Huang, Kamalan Jeevaratnam
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 27, Iss , Pp 100753- (2021)
Mitochondrial dysfunction underlying metabolic disorders such as obesity and diabetes mellitus is strongly associated with cardiac arrhythmias. Murine Pgc-1α−/− hearts replicate disrupted mitochondrial function and model the associated pro-arrhy
Externí odkaz:
https://doaj.org/article/5b3313281d784c3081ca659d1886a157
Autor:
Khalil Saadeh, Ibrahim Talal Fazmin
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Incidence of cardiac arrhythmias increases significantly with age. In order to effectively stratify arrhythmic risk in the aging population it is crucial to elucidate the relevant underlying molecular mechanisms. The changes underlying age-related el
Externí odkaz:
https://doaj.org/article/f21a47a108a241fc95ccc91b9164af7f
Autor:
Khalil Saadeh, Joanna B Aitken, Sharmini Julita Paramasivam, Peter Cockcroft, Kamalan Jeevaratnam
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0249669 (2021)
The transition into the clinical environment is challenging and associated with significant stress and anxiety. This study aimed to examine the perspectives of students on the characteristics important for preparedness for clinical learning and the i
Externí odkaz:
https://doaj.org/article/85888657a1e44e918bafa6488ceab562
Publikováno v:
Leukemia & Lymphoma. 64:725-729
Publikováno v:
Subcellular Biochemistry ISBN: 9783031265754
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c347b72e32d93a09f6ed811fb2bca9ec
https://doi.org/10.1007/978-3-031-26576-1_10
https://doi.org/10.1007/978-3-031-26576-1_10
Transcriptional profiles of genes related to electrophysiological function in Scn5a+/- murine hearts
Autor:
Samantha C. Salvage, Kamalan Jeevaratnam, Charlotte E. Edling, Michael Takla, Gary Tse, Khalil Saadeh, Christopher L.-H. Huang, Kevin Zhang
Publikováno v:
Physiological Reports, Vol 9, Iss 19, Pp n/a-n/a (2021)
Funder: University of Surrey; Id: http://dx.doi.org/10.13039/501100003513
The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initi
The Scn5a gene encodes the major pore‐forming Nav1.5 (α) subunit, of the voltage‐gated Na+ channel in cardiomyocytes. The key role of Nav1.5 in action potential initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1441935c644dcf3b2a59408139218e50
Autor:
Kamalan Jeevaratnam, N Nanthakumar, Khalil Saadeh, Charlotte E. Edling, C Huang, Shiraz Ahmad, Karan R. Chadda, H Valli, Ibrahim T. Fazmin
Publikováno v:
European Heart Journal. 42
Background The risk of cardiac arrhythmias increases significantly in patients with metabolic disorders such as obesity and diabetes mellitus. The mechanisms linking metabolic conditions and electrophysiological changes underlying cardiac arrhythmias