Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Khalil Bouyakdan"'
Autor:
Shingo Nakajima, Geneviève Demers, Arturo Israel Machuca-Parra, Zahra Dashtehei Pour, Diane Bairamian, Khalil Bouyakdan, Alexandre Fisette, Anita Kabahizi, Josephine Robb, Demetra Rodaros, Cyril Laurent, Guillaume Ferreira, Nathalie Arbour, Thierry Alquier, Stephanie Fulton
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract G protein-coupled receptor 120 (GPR120, Ffar4) is a sensor for long-chain fatty acids including omega-3 polyunsaturated fatty acids (n-3 PUFAs) known for beneficial effects on inflammation, metabolism, and mood. GPR120 mediates the anti-infl
Externí odkaz:
https://doaj.org/article/f87ce8b1f2204c9eb17e5b7be56e1bd7
Autor:
Alexandria Béland-Millar, Alexia Kirby, Yen Truong, Julie Ouellette, Sozerko Yandiev, Khalil Bouyakdan, Chantal Pileggi, Shama Naz, Melissa Yin, Micaël Carrier, Pavel Kotchetkov, Marie-Kim St-Pierre, Marie-Ève Tremblay, Julien Courchet, Mary-Ellen Harper, Thierry Alquier, Claude Messier, Adam J. Shuhendler, Baptiste Lacoste
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112485- (2023)
Summary: Neurovascular abnormalities in mouse models of 16p11.2 deletion autism syndrome are reminiscent of alterations reported in murine models of glucose transporter deficiency, including reduced brain angiogenesis and behavioral alterations. Yet,
Externí odkaz:
https://doaj.org/article/80b98b8bcdd8414481360ac28e85ff5a
Autor:
Alexandre Fisette, Stephanie Tobin, Léa Décarie-Spain, Khalil Bouyakdan, Marie-Line Peyot, S.R. Murthy Madiraju, Marc Prentki, Stephanie Fulton, Thierry Alquier
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1217-1226 (2016)
Summary: α/β-Hydrolase domain 6 (ABHD6) is a monoacylglycerol hydrolase that degrades the endocannabinoid 2-arachidonoylglycerol (2-AG). Although complete or peripheral ABHD6 loss of function is protective against diet-induced obesity and insulin r
Externí odkaz:
https://doaj.org/article/38c0435357f247599bf5d59aad540d0a
Autor:
Daniel Oropeza, Nathalie Jouvet, Khalil Bouyakdan, Gabrielle Perron, Lea-Jeanne Ringuette, Louis H. Philipson, Robert S. Kiss, Vincent Poitout, Thierry Alquier, Jennifer L. Estall
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 811-822 (2015)
Objectives: Peroxisome proliferator-activated receptor γ coactivator 1 (PPARGCA1, PGC-1) transcriptional coactivators control gene programs important for nutrient metabolism. Islets of type 2 diabetic subjects have reduced PGC-1α expression and thi
Externí odkaz:
https://doaj.org/article/1935dd6aa91c47d5ae94162df6f8e61d
Autor:
Khalil Bouyakdan, Romane Manceau, Josephine L. Robb, Demetra Rodaros, Stephanie Fulton, Thierry Alquier
Publikováno v:
Journal of Neuroendocrinology. 34
Acyl-CoA binding protein (ACBP), also known as diazepam binding inhibitor (DBI), has recently emerged as a hypothalamic and brainstem gliopeptide regulating energy balance. Previous work has shown that the ACBP-derived octadecaneuropeptide exerts str
Autor:
Khalil Bouyakdan, Cindy Baldwin, Scott A. Campbell, Maureen Gannon, Thierry Alquier, Vincent Poitout, Nathalie Jouvet, Jennifer L. Estall, Shannon E. Townsend
Publikováno v:
Diabetes
Controllable genetic manipulation is an indispensable tool in research, greatly advancing our understanding of cell biology and physiology. However in β-cells, transgene silencing, low inducibility, ectopic expression, and off-targets effects are pe
Autor:
MARIA GALIPEAU, NATHALIE JOUVET, EMILIE COURTY, ROXANNE VANDENBEEK, NAVEEN P. KHAN, KHALIL BOUYAKDAN, CUILAN NIAN, CATERINA IORIO, DANIEL D. SCOTT, MAY FARAJ, MARLENE OEFFINGER, FRANCIS C. LYNN, ROBERT A. SCREATON, THIERRY ALQUIER, JENNIFER L. ESTALL
Publikováno v:
Diabetes. 71
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1A) is a nuclear transcriptional coregulator that plays a major role in the control of metabolism and mitochondrial biogenesis. We showed that a diabetes-linked single nucleotid
Autor:
Jennifer L. Estall, Thierry Alquier, Vincent Poitout, Maureen A. Gannon, Shannon E. Townsend, Cindy Baldwin, Scott A. Campbell, Khalil Bouyakdan, Nathalie Jouvet
Controllable genetic manipulation is an indispensable tool in research, greatly advancing our understanding of cell biology and physiology. However in beta cells, transgene silencing, low inducibility, ectopic expression and off-targets effects are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc3b9f40a9d43fbf3b1ebae5ad0278c
https://doi.org/10.2337/figshare.16713151
https://doi.org/10.2337/figshare.16713151
Autor:
Thierry Alquier, Roxanne Vandenbeek, Emilie Courty, Khalil Bouyakdan, Jennifer L. Estall, Nathalie Jouvet, Maria Galipeau
Publikováno v:
Canadian Journal of Diabetes. 45:S8-S9
Autor:
Jennifer L. Estall, Khalil Bouyakdan, Thierry Alquier, Baldwin C, Nathalie Jouvet, Jadwiga Marcinkiewicz
Controllable genetic manipulation is an indispensable tool in research, greatly advancing our understanding of cell biology and physiology. However, in beta cells, transgene silencing, low inducibility, ectopic expression and off-targets effects on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::835c711d9835ee514c2086983afda398
https://doi.org/10.1101/2021.02.10.430692
https://doi.org/10.1101/2021.02.10.430692