Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Khalid H. Bhat"'
Autor:
Khalid H. Bhat, Saurabh Priyadarshi, Sarah Naiyer, Xinyan Qu, Hammad Farooq, Eden Kleiman, Jeffery Xu, Xue Lei, Jose F. Cantillo, Robert Wuerffel, Nicole Baumgarth, Jie Liang, Ann J. Feeney, Amy L. Kenter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Here the authors show enhancers in the Igh locus play a major role in configuring locus architecture and in V(D)J recombination, and identify a link between enhancer hub formation, locus contraction and cohesin-mediated loop extrusion.
Externí odkaz:
https://doaj.org/article/ba000a65998d49268875ffe123c8814e
Autor:
Khalid H. Bhat, Saurabh Priyardarshi, Sarah Naiyer, X. Qu, Hammad Farooq, Eden Kleiman, J. Xu, X. Lei, Jose F. Cantillo, Robert Wuerffel, Nicole Baumgarth, Jie Liang, Ann J. Feeney, Amy L. Kenter
The Igh locus is organized into a developmentally regulated topologically associated domain (TAD) that is divided into subTADs. Here we identify a series of novel enhancers (NEs) that collaborate to configure the locus, determine transcriptional pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838df64ddbff55c839150c2b816a2171
https://doi.org/10.1101/2022.05.23.492988
https://doi.org/10.1101/2022.05.23.492988
