Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Khalid Amine Timani"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
To date, there are a small number of nuclear-restricted proteins that have been reported to play a role in NF-κB signaling. However, the exact molecular mechanisms are not fully understood. Tip110 is a nuclear protein that has been implicated in mul
Externí odkaz:
https://doaj.org/article/c8ff096bb2044b00bebb03976106c9ad
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-6 (2018)
Abstract Tip110, an important regulator of several oncogenic proteins, was significantly downregulated in human metastatic melanoma cells exposed to a hypoxic condition. Therefore, in this study, we set to determine whether differential expression of
Externí odkaz:
https://doaj.org/article/204ef1ce9d8f4b4d9e061ee58e4a5e0c
Publikováno v:
Stem Cells and Development. 27:566-576
Tip110 plays important roles for stem cell pluripotency and hematopoiesis. However, little is known about the regulatory mechanisms of Tip110 expression in this process. In this study, we first sho...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5aa47f32ca96b485c71022f2846f94a
https://doi.org/10.1089/scd.2017.0197
https://doi.org/10.1089/scd.2017.0197
Publikováno v:
Oncotarget
Tip110 expression regulates hematopoiesis, but the regulatory mechanisms during hematopoiesis are not fully understood. There are a number of putative microRNA (miRNA) binding sites identified within the Tip110 3' untranslated region (3'UTR). In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254a4a010f33ba21ddadeabbe81a136b
https://doi.org/10.18632/oncotarget.23572
https://doi.org/10.18632/oncotarget.23572
Autor:
Chris Sanburns, Johnny J. He, Lu Li, Ying Liu, Yinghua Niu, Khalid Amine Timani, Victor L. He, Jiafeng Xie
Publikováno v:
J Neurovirol
Astrocytes are susceptible to HIV infection and potential latent HIV reservoirs. Tat is one of three abundantly expressed HIV early genes in HIV-infected astrocytes and has been shown to be a major pathogenic factor for HIV/neuroAIDS. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e70eac089bbff2cd8514e6c27fb432
https://europepmc.org/articles/PMC6750972/
https://europepmc.org/articles/PMC6750972/
Publikováno v:
Virus Research. 223:161-169
HIV-1 Nef is necessary and may be sufficient for HIV-1-associated AIDS pathogenicity, in that knockout of Nef alone can protect HIV-infected patients from AIDS. We therefore investigated the feasibility of physical knockout of Nef, using the host ubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0088336326f81116e54ee364c8c13a97
https://doi.org/10.1016/j.virusres.2016.07.009
https://doi.org/10.1016/j.virusres.2016.07.009
Publikováno v:
Current HIV Research. 13:55-63
Human immunodeficiency virus type 1 (HIV-1) Tat protein is a major pathogenic factor in HIV-associated neurological diseases; it exhibits direct neurotoxicity and indirect astrocyte-mediated neurotoxicity. We have shown that Tat alone is capable of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446fd73720a80b2747eab9291c3c838b
https://doi.org/10.2174/1570162x13666150121115804
https://doi.org/10.2174/1570162x13666150121115804
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 54:10-19
Tip110 is a nuclear protein and has been shown to function in tumor antigenicity, regulation of gene transcription, pre-mRNA splicing, stem cell proliferation and differentiation, and embryonic development. To characterize the in vivo functions of Ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9508e15686ba7a30bad96bd5ad967d
https://doi.org/10.1016/j.biocel.2014.06.017
https://doi.org/10.1016/j.biocel.2014.06.017
Autor:
Jiafeng Xie, Chris Sanborn, Ying Liu, Yinghua Niu, Khalid Amine Timani, Victor L. He, Lu Li, Johnny J. He
Publikováno v:
Journal of NeuroVirology. 25:901-901
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::538875b660aa962b7ed3bacdbb5c3884
https://doi.org/10.1007/s13365-019-00766-7
https://doi.org/10.1007/s13365-019-00766-7
Publikováno v:
Stem cells (Dayton, Ohio). 35(7)
HIV-1 Tat-interacting protein of 110 kDa, Tip110, plays important roles in multiple biological processes. In this study, we aimed to characterize the function of Tip110 in embryonic development. Transgenic mice lacking expression of a functional Tip1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcfc41d4034bb8d82578c00e439d800
https://pubmed.ncbi.nlm.nih.gov/28436127
https://pubmed.ncbi.nlm.nih.gov/28436127