Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Khalid A. Al-Rashood"'
Autor:
Ghada H. Al-Ansary, Wagdy M. Eldehna, Hazem A. Ghabbour, Sara T. A. Al-Rashood, Khalid A. Al-Rashood, Radwa A. Eladwy, Abdullah Al-Dhfyan, Maha M. Kabil, Hatem A. Abdel-Aziz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 986-991 (2017)
Cancer stem cells (CSCs) have been objects of intensive study since their identification in 1994. Adopting a structural rigidification approach, a novel series of 3-phenylthiazolo[3,2-a]benzimidazoles 4a–d was designed and synthesised, in an attemp
Externí odkaz:
https://doaj.org/article/02f9a0e9954840abb435b4fc96bbfce4
Publikováno v:
Molecules, Vol 15, Iss 6, Pp 3775-3815 (2010)
The present review covers the recent synthetic strategies and chemical transformations of thiazolo[3,2-a]benzimidazoles and it also presents the highlights of the biological activities of these compounds.
Externí odkaz:
https://doaj.org/article/dd5baacec2de44ec9859bddcb1b175b1
Publikováno v:
Journal of Chemistry, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/563ead5d640c475e828ccce13f9b17c9
Autor:
Ali S. Abdelhameed, Adnan A. Kadi, Hatem A. Abdel-Aziz, Rihab F. Angawi, Mohamed W. Attwa, Khalid A. Al-Rashood
Publikováno v:
The Scientific World Journal, Vol 2014 (2014)
A new approach was recently introduced to improve the structure elucidation power of tandem mass spectrometry simulating the MS3 of ion trap mass spectrometry system overcoming the different drawbacks of the latter. The fact that collision induced di
Externí odkaz:
https://doaj.org/article/0b20fd0dbeed40e0bfb515d077780f32
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 8, Pp o2369-o2369 (2012)
The molecule of the title compound, C15H15NO3S, has a twisted U-shaped conformation: the twist occurs at the central C—S(=O)2—C—C—C unit and the benzene ring makes a dihedral angle of 28.74 (7)° with the phenyl ring. The S—C—C=N torsion
Externí odkaz:
https://doaj.org/article/b608c56e2949441d98e954173b53dbf6
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 4, Pp o1033-o1033 (2012)
In the title compound, C15H14O3S, the benzene and phenyl rings make a dihedral angle of 33.56 (16)°. In the crystal, molecules are linked by C—H...O hydrogen bonds into a layer parallel to the ab plane.
Externí odkaz:
https://doaj.org/article/206d508949dd4daabc4022330bea41a3
Autor:
Hoong-Kun Fun, Suchada Chantrapromma, Hazem A. Ghabbour, Hatem A. Abdel-Aziz, Khalid A. Al-Rashood
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o612-o613 (2012)
In the title molecule, C12H12N4S, the thiophene ring is disordered over two orientations with a refined site-occupancy ratio of 0.777 (4):0.223 (4). The pyrazolopyridine ring system is essentially planar with an r.m.s. deviation of 0.0069 (3) Å and
Externí odkaz:
https://doaj.org/article/d66572825702451a94cd484173fb7389
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o628-o628 (2012)
In the title compound, C12H14N2O, the imidazole ring forms a dihedral angle of 66.73 (5)° with the phenyl ring. In the crystal, molecules are linked via O—H...N and C—H...O hydrogen bonds into sheets lying parallel to (100). The crystal structur
Externí odkaz:
https://doaj.org/article/d2704c86f7194c2e87aece6571ce0a2f
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 10, Pp o2623-o2624 (2011)
The title compound, C25H22N2O4S, features a tetra-substituted pyrazole ring. The dihedral angles formed between the five-membered ring (r.m.s. deviation = 0.007 Å) and the N- and C-bound phenyl rings are 48.10 (7) and 72.01 (7) °, respectively, ind
Externí odkaz:
https://doaj.org/article/92288788181049a0a03ea68e21fe10e6
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 164:1-8
Suvorexant is a novel sedative/hypnotic drug approved for treatment of insomnia. It has significant forensic importance due to its hypnotic and depressant effects on central nervous system. In this study, a highly sensitive UPLC-MS/MS assay was devel