Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Khalid A. Agha"'
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Akademický článek
Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR co-agonist: simulation-guided analogue design and pharmacological screening
Autor: Khalid A. Agha, Nader E. Abo-Dya, Abdul Rashid Issahaku, Clement Agoni, Mahmoud E. S. Soliman, Eatedal H. Abdel-Aal, Zakaria K. Abdel-Samii, Tarek S. Ibrahim
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1241-1256 (2022)
An efficient method for synthesising NMDAR co-agonist Sunifiram (DM235), in addition to Sunifram-carbamate and anthranilamide hybrids, has been developed in high yields via protecting group-free stepwise unsymmetric diacylation of piperazine using N-
Externí odkaz: https://doaj.org/article/4e635989cfea448eab1877e1019864be
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N-Acylbenzotriazole: convenient approach for protecting group-free monoacylation of symmetric diamines
Autor: Nader E. Abo-Dya, Zakaria K. Abdel-Samii, Khalid A. Agha, Tarek S. Ibrahim, Eatedal H. Abdel-Aal
Publikováno v: Monatshefte für Chemie - Chemical Monthly. 151:589-598
An efficient green route for monoacylation of aromatic diamines, namely o-phenylenediamine and p-phenylenediamine and aliphatic diamines ethylenediamine and piperazine using N-acylbenzotriazoles (NABs) in n-butanol was developed. The new protocol doe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52d127f800636381e55a86cf1470c3b5
https://doi.org/10.1007/s00706-020-02579-5
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6
Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity
Autor: Nader E. Abo-Dya, Eatedal H. Abdel-Aal, Tarek S. Ibrahim, Zakaria K. Abdel-Samii, Khalid A. Agha, Nehal M. Elsherbiny, Mohamed El-Sherbiny
Publikováno v: Bioorganic chemistry. 114
Cisplatin (CP) is an effective chemotherapeutic agent for treatment of various types of cancer, however efforts are needed to reduce its toxic side effect. Previous studies revealed promising effect of peptides in decreasing CP induced nephrotoxicity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::093cad7e0fbcd3f7e7796455f435f8c7
https://pubmed.ncbi.nlm.nih.gov/34246972
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7
Benzotriazole-Mediated Synthesis and Antibacterial Activity of Novel N-Acylcephalexins
Autor: Khalid A. Agha, Tarek S. Ibrahim, Wael A H Hegazy, Eatedal H. Abdel-Aal, Nader E. Abo-Dya
Publikováno v: Scientia Pharmaceutica
Volume 84
Issue 3
Pages 484-496
Cephalexin (1) was acylated using N-acylbenzotriazoles (3a–k′) derived from various carboxylic acids including aromatic, heterocyclic and N-Pg-α-amino acid to afford N-acylcephalexins in excellent yields (82%–96%). Antibacterial screening of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05604adba61efb701e21f382a4cc294
https://doi.org/10.3390/scipharm84030484
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Physico-Chemical Environment Of Coastal Areas In The Vicinity Of Lbod And Tidal Link Drain In Sindh, Pakistan After Cyclone 2A
Autor: Salam Khalid Al-Agha, Inamullah Bhatti, Hossam Adel Zaqoot, Shaukat Hayat Khan, Abdul Khalique Ansari
This paper presents the results of preliminary assessment of water quality along the coastal areas in the vicinity of Left Bank Outfall Drainage (LBOD) and Tidal Link Drain (TLD) in Sindh province after the cyclone 2A occurred in 1999. The water samp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c757e03931d5469ff04dd68d9d7033d
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