Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Khalid A Mohamedali"'
Autor:
Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Timothy G Whitsett, Jeffrey A Winkles, Walter N Hittelman, Michael G Rosenblum
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Antibody-drug conjugates are an exceptional and useful therapeutic tool for multiple diseases, particularly for cancer treatment. We previously showed that the fusion of the serine protease granzyme B (GrB), the effector molecule or T and
Externí odkaz:
https://doaj.org/article/12c629aa49a34d43add526d6194f842b
Autor:
Lawrence H. Cheung, Yunli Zhao, Ana Alvarez-Cienfuegos, Khalid A. Mohamedali, Yu J. Cao, Walter N. Hittelman, Michael G. Rosenblum
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Immunotherapeutic approaches designed to augment T and B cell mediated killing of tumor cells has met with clinical success in recent years suggesting tremendous potential for treatment in a broad spectrum of tumor types. After co
Externí odkaz:
https://doaj.org/article/385fcf50e0a246b1a69551338e570547
Autor:
Michael G. Rosenblum, Nhan L. Tran, Jeffrey A. Winkles, Walter N. Hittelman, Yuan Qi, Xiudong Lei, Janine LoBello, Lawrence H. Cheung, Mary Migliorini, Yu Cao, Ana Maria Gonzalez-Angulo, Khalid A. Mohamedali, Hong Zhou
Supplementary Figures 1-8. Supplementary Figure 1: TWEAK is internalized and degraded following binding to Fn14-positive cells Supplementary Figure 2: Surface plasmon resonance analysis of TWEAK Supplementary Figure 3: GrB-TWEAK specifically internal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f699c8a82be2f270e9b2b2f6c66f0b
https://doi.org/10.1158/1535-7163.22501878.v1
https://doi.org/10.1158/1535-7163.22501878.v1
Autor:
Michael G. Rosenblum, Nhan L. Tran, Jeffrey A. Winkles, Walter N. Hittelman, Yuan Qi, Xiudong Lei, Janine LoBello, Lawrence H. Cheung, Mary Migliorini, Yu Cao, Ana Maria Gonzalez-Angulo, Khalid A. Mohamedali, Hong Zhou
Supplementary materials and methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dda76b441c2c569bfa40e6b02eda224
https://doi.org/10.1158/1535-7163.22501869.v1
https://doi.org/10.1158/1535-7163.22501869.v1
Supplementary Figures - PDF file 791K, Supplementary Figure 1. Representative image showing selective detection of CD-31+ pixels using MetaMorph 7.7 imaging software. The original image is shown in Figure 6B. Supplementary Figure 2. Original whole ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9130f4a6762da51322bfecbe0a8eff57
https://doi.org/10.1158/1535-7163.22498407.v1
https://doi.org/10.1158/1535-7163.22498407.v1
Autor:
Michael G. Rosenblum, Nhan L. Tran, Jeffrey A. Winkles, Walter N. Hittelman, Yuan Qi, Xiudong Lei, Janine LoBello, Lawrence H. Cheung, Mary Migliorini, Yu Cao, Ana Maria Gonzalez-Angulo, Khalid A. Mohamedali, Hong Zhou
Supplementary Tables 1-4. Supplementary Table 1: In vitro cytotoxicity of GrB-TWEAK Supplementary Table 2: TNBC cell lines are highly sensitive to GrB-Fc-IT4 cytotoxicity Supplementary Table 3: GrB-TWEAK and GrB-Fc-IT4 circumvent MDR1-mediated multid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb20287e4bc7dda28fc0a47b19629bd
https://doi.org/10.1158/1535-7163.22501872
https://doi.org/10.1158/1535-7163.22501872
Autor:
Nora M. Navone, Michael G. Rosenblum, Wendy Zhang, Sehoon Kim, Jun Yang, Xinhai Wan, Michael W. Starbuck, Zhi Gang Li, Khalid A. Mohamedali
Purpose: A hallmark of prostate cancer (PCa) progression is the development of osteoblastic bone metastases, which respond poorly to available therapies. We previously reported that VEGF121/rGel targets osteoclast precursors and tumor neovasculature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cac3f21ee94d3bbef5f824907a1ccb
https://doi.org/10.1158/1078-0432.c.6519315.v1
https://doi.org/10.1158/1078-0432.c.6519315.v1
Autor:
Nora M. Navone, Michael G. Rosenblum, Wendy Zhang, Sehoon Kim, Jun Yang, Xinhai Wan, Michael W. Starbuck, Zhi Gang Li, Khalid A. Mohamedali
Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33789fb4ef43dd30274ba2d55e7f9c00
https://doi.org/10.1158/1078-0432.22442637.v1
https://doi.org/10.1158/1078-0432.22442637.v1
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
The pathophysiology of tumor growth following skeletal metastases and the poor response of this type of lesion to therapeutic intervention remains incompletely understood. Vascular endothelial growth factor (VEGF)-A and its receptors play a role in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3be43809ff188551cbbd5aacc00d1
https://doi.org/10.1158/0008-5472.c.6494972
https://doi.org/10.1158/0008-5472.c.6494972
Autor:
Michael G. Rosenblum, Bryant G. Darnay, Philip E. Thorpe, Nora M. Navone, Charles R. Sikes, Ann T. Poblenz, Khalid A. Mohamedali
Supplementary Figure 2 from Inhibition of Prostate Tumor Growth and Bone Remodeling by the Vascular Targeting Agent VEGF121/rGel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a0548d034516cab145575cf6120866
https://doi.org/10.1158/0008-5472.22366061
https://doi.org/10.1158/0008-5472.22366061