Synthetic SARS-CoV-2 Spike-Based DNA Vaccine Elicits Robust and Long-Lasting Th1 Humoral and Cellular Immunity in Mice

Autor: Sawsan S. Alamri, Khalid A. Alluhaybi, Rowa Y. Alhabbab, Mohammad Basabrain, Abdullah Algaissi, Sarah Almahboub, Mohamed A. Alfaleh, Turki S. Abujamel, Wesam H. Abdulaal, M-Zaki ElAssouli, Rahaf H. Alharbi, Mazen Hassanain, Anwar M. Hashem

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

The ongoing global pandemic of coronavirus disease 2019 (COVID-19) calls for an urgent development of effective and safe prophylactic and therapeutic measures. The spike (S) glycoprotein of severe acute respiratory syndrome-coronavirus (SARS-CoV-2) i

Externí odkaz: https://doaj.org/article/f06cd1e46e344052adf163bca47a890d

Early Humoral Response Correlates with Disease Severity and Outcomes in COVID-19 Patients

Autor: Anwar M. Hashem, Abdullah Algaissi, Sarah A. Almahboub, Mohamed A. Alfaleh, Turki S. Abujamel, Sawsan S. Alamri, Khalid A. Alluhaybi, Haya I. Hobani, Rahaf H. AlHarbi, Reem M. Alsulaiman, M-Zaki ElAssouli, Sharif Hala, Naif K. Alharbi, Rowa Y. Alhabbab, Ahdab A. AlSaieedi, Wesam H. Abdulaal, Abdullah Bukhari, Afrah A. AL-Somali, Fadwa S. Alofi, Asim A. Khogeer, Arnab Pain, Almohanad A. Alkayyal, Naif A. M. Almontashiri, Bakur Mahmoud Ahmad, Xuguang Li

Publikováno v: Viruses, Vol 12, Iss 12, p 1390 (2020)

The Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, continues to spread globally with significantly high morbidity and mortality rates. Antigen-specific responses are of unquestionable value for clinical management of COVID-19 patients. He

Externí odkaz: https://doaj.org/article/6abdd5c2c73d44ecbdd5b3fbedf84173

Early Humoral Response Correlates with Disease Severity and Outcomes in COVID-19 Patients

Autor: Mohamed A. Alfaleh, Rowa Y. Alhabbab, M-Zaki ElAssouli, Naif Khalaf Alharbi, Reem M. Alsulaiman, Sharif Hala, Arnab Pain, Haya I. Hobani, Almohanad A. Alkayyal, Wesam H. Abdulaal, Asim Khogeer, Rahaf H. Alharbi, Sawsan S. Al-amri, Khalid A Alluhaybi, Turki S. Abujamel, Xuguang Li, Afrah Alsomali, Bakur Mahmoud Ahmad, Abdullah Bukhari, Abdullah Algaissi, Sarah A Almahboub, Anwar M. Hashem, Fadwa S. Alofi, Naif A.M. Almontashiri, Ahdab AlSaieedi

Publikováno v: Viruses, Vol 12, Iss 1390, p 1390 (2020)
Viruses
Viruses; Volume 12; Issue 12; Pages: 1390

The Coronavirus Disease 2019 (COVID-19), caused by the novel SARS-CoV-2, continues to spread globally with significantly high morbidity and mortality rates. Immunological surrogate markers, in particular antigen-specific responses, are of unquestiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312c2d30e057f3e21851fd4f2013056a
https://www.mdpi.com/1999-4915/12/12/1390

Multiple Indirect ELISAs for Serological Detection of SARS-CoV-2 Antibodies

Autor: Mohammad Zaki ElAssouli, Reem M. Alsulaiman, Ahmad Bakur Mahmoud, Mohamed A. Alfaleh, Afrah Alsomali, Rahaf H. Alharbi, Arnab Pain, Khalid A Alluhaybi, Anwar M. Hashem, Naif A.M. Almontashiri, Sherif Hala, Abdullah Algaissi, Haya I. Hobani, Wesam H. Abdulaal, Fadwa S. Alofi, SawsanS. Alamari, Almohanad A. Alkayyal, Asim Khogeer, Turki S. Abujamel

As the coronavirus disease 2019 (COVID-19), which is caused by the novel coronavirus SARS-CoV-2, continues to spread rapidly around the world, there is an urgent need for validated serological assays to evaluate viral specific antibody responses in C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557a44a547052f466412550177ae4b80

Early Humoral Response Correlates with Disease Severity and Outcomes in COVID-19 Patients.

Autor: Hashem, Anwar M.^1,2 (AUTHOR) salmahboob@kau.edu.sa, Algaissi, Abdullah^3,4 (AUTHOR) aalgaissi@jazanu.edu.sa, Almahboub, Sarah A.¹ (AUTHOR) maalfaleh@kau.edu.sa, Alfaleh, Mohamed A.^1,5 (AUTHOR) tabujamel@kau.edu.sa, Abujamel, Turki S.^1,6 (AUTHOR) sawsan522@hotmail.com, Alamri, Sawsan S.^1,7 (AUTHOR) Kalluhaybi@kau.edu.sa, Alluhaybi, Khalid A.^1,5 (AUTHOR) haya.ibmh@gmail.com, Hobani, Haya I.¹ (AUTHOR) rahafh_h@live.com, AlHarbi, Rahaf H.¹ (AUTHOR) ralsulaiman@kau.edu.sa, Alsulaiman, Reem M.¹ (AUTHOR) mzassouli@hotmail.com, ElAssouli, M-Zaki¹ (AUTHOR) ralhabbab2@gmail.com, Hala, Sharif⁸ (AUTHOR) sharif.hala@kaust.edu.sa, Alharbi, Naif K.⁹ (AUTHOR) harbina2@ngha.med.sa, Alhabbab, Rowa Y.^1,6 (AUTHOR) aalsaieedi@kau.edu.sa, AlSaieedi, Ahdab A.^1,6 (AUTHOR), Abdulaal, Wesam H.⁷ (AUTHOR), Bukhari, Abdullah¹⁰ (AUTHOR) ab.bukhari@gmail.com, AL-Somali, Afrah A.¹¹ (AUTHOR) afaalsomali@moh.gov.sa, Alofi, Fadwa S.¹² (AUTHOR) fsalofi@moh.gov.sa, Khogeer, Asim A.¹³ (AUTHOR) akhogeer@moh.gov.sa

Publikováno v: Viruses (1999-4915). Dec2020, Vol. 12 Issue 12, p1390. 1p.