Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Khaled S Abd-Elrahman"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 8, Pp 1635-1636 (2024)
Externí odkaz:
https://doaj.org/article/b8e540eef0b5426e9714527245b2b4aa
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1a9fc9390a134f35b8597d1cf896e3d2
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Repressor element 1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) is a transcription repressor and its expression is regulated by the Wnt pathway through β-catenin. Metabotropic glutamate receptor 5 (mGluR5)
Externí odkaz:
https://doaj.org/article/207182bafc104c7290e2a5ccbdf8f569
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment. There are currently no available disease modifying treatments for HD patients. We have previously show
Externí odkaz:
https://doaj.org/article/59c9292dce2c4774be4a99099905c3ea
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-9 (2019)
Abstract Huntington’s disease (HD) is a neurodegenerative disorder caused by a genetic abnormality in the huntingtin gene that leads to a polyglutamine repeat expansion of the huntingtin protein. The cleaved polyglutamine expansion of mutant huntin
Externí odkaz:
https://doaj.org/article/0d229b0c163b4f0f90242ef745e4b248
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Alzheimer’s disease (AD) is characterized by neurotoxicity mediated by the accumulation of beta amyloid (Aβ) oligomers, causing neuronal loss and progressive cognitive decline. Genetic deletion or chronic pharmacological inhibition of mGl
Externí odkaz:
https://doaj.org/article/837d5bcb12f0440aaac2e7c5836b767c
Publikováno v:
Annual Review of Pharmacology and Toxicology. 62:235-254
Metabotropic glutamate receptor 5 (mGluR5) is ubiquitously expressed in brain regions responsible for memory and learning. It plays a key role in modulating rapid changes in synaptic transmission and plasticity. mGluR5 supports long-term changes in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31aeb314ce0f9457356166d224f20c28
https://doi.org/10.1146/annurev-pharmtox-021821-091747
https://doi.org/10.1146/annurev-pharmtox-021821-091747
Publikováno v:
Canadian Journal of Civil Engineering. 48:925-940
The critical need to enhance existing strengthening methods with more efficient and effective ones has led to the evolvement of smarter and innovative class of materials termed shape memory alloys (SMA). The SMAs possess unique characteristic propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be37f6b86862c82ffd1390f268cbd23d
https://doi.org/10.1139/cjce-2019-0511
https://doi.org/10.1139/cjce-2019-0511
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:74-84
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease that leads to progressive motor impairments with no available disease-modifying treatment. Current evidence indicates that exacerbated postsynaptic glutamate signaling in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a30a235bc9616fc27ce7b8bedc0d9b
https://doi.org/10.1124/jpet.121.000735
https://doi.org/10.1124/jpet.121.000735
Autor:
Safaa H. Hammoud, Khaled S. Abd-Elrahman, Ali H. Eid, Rana Alaaeddine, Ahmed F. El-Yazbi, Aya Arakji, Ibrahim AlZaim
Publikováno v:
Clinical Science. 135:1015-1051
Antithrombotic drugs are widely used for primary and secondary prevention, as well as treatment of many cardiovascular disorders. Over the past few decades, major advances in the pharmacology of these agents have been made with the introduction of ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dbe93e7019b7512d75d430889e1f0e
https://doi.org/10.1042/cs20201445
https://doi.org/10.1042/cs20201445