Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Khaled Moussawi"'
Autor:
Osama Ahmed, Kingsley M. Ekumi, Francesco V. Nardi, Gulimiheranmu Maisumu, Khaled Moussawi, Eric D. Lazartigues, Bo Liang, Abraam M. Yakoub
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Gene delivery to, and expression in, the mouse brain is important for understanding gene functions in brain development and disease, or testing gene therapies. Here, we describe an approach to express a transgene in the mouse brain in a cell
Externí odkaz:
https://doaj.org/article/3fb73528200548d7b16bc0114b0e7fd5
Publikováno v:
Brain Stimulation, Vol 15, Iss 1, Pp 23-31 (2022)
Background: Deep Brain Stimulation (DBS) of the subthalamic nucleus or globus pallidus internus is used to treat the motor symptoms of Parkinson's disease. The former can worsen impulsive and compulsive behaviors after controlling for the reduction o
Externí odkaz:
https://doaj.org/article/eb126600740946189c2c0bcbc1641d29
Publikováno v:
Bio-Protocol, Vol 11, Iss 10 (2021)
Models of drug addiction in rodents are instrumental in understanding the underlying neurobiology. Intravenous self-administration of drugs in mice is currently the most commonly used model; however, several challenges exist due to complications rela
Externí odkaz:
https://doaj.org/article/9a4e625be401429bbad1aa99750e8fa2
Publikováno v:
eLife, Vol 10 (2021)
Ultrapotent chemogenetics, including the chloride-permeable inhibitory PSAM4-GlyR receptor, were recently proposed as a powerful strategy to selectively control neuronal activity in awake, behaving animals. We aimed to validate the inhibitory functio
Externí odkaz:
https://doaj.org/article/7449ab2676034253b79760799f82b4f7
Publikováno v:
eLife, Vol 9 (2020)
The dorsal raphe nucleus is the predominant source of central serotonin, where neuronal activity regulates complex emotional behaviors. Action potential firing of serotonin dorsal raphe neurons is driven via α1-adrenergic receptors (α1-AR) activati
Externí odkaz:
https://doaj.org/article/463104f2681c4d35bedabc965ca4decf
Publikováno v:
eNeurologicalSci, Vol 13, Iss , Pp 24-25 (2018)
Hypercalcemia from tumors has been associated with Posterior Reversible Encephalopathy Syndrome (PRES) but the mechanism remains unclear. In this article, we describe a case of PRES caused by hypercalcemia from lymphoma. We summarize the available sc
Externí odkaz:
https://doaj.org/article/bae05a5cd7564bdfb3efe2bdc98836c0
Autor:
Juho Joutsa, Khaled Moussawi, Shan H. Siddiqi, Amir Abdolahi, William Drew, Alexander L. Cohen, Thomas J. Ross, Harshawardhan U. Deshpande, Henry Z. Wang, Joel Bruss, Elliot A. Stein, Nora D. Volkow, Jordan H. Grafman, Edwin van Wijngaarden, Aaron D. Boes, Michael D. Fox
Publikováno v:
Nature Medicine. 28:1249-1255
Drug addiction is a public health crisis for which new treatments are urgently needed. In rare cases, regional brain damage can lead to addiction remission. These cases may be used to identify therapeutic targets for neuromodulation. We analyzed two
Cell type and sex specific insights into ventral striatum deep brain stimulation for cocaine relapse
Autor:
Collin M, Lehmann, Khaled, Moussawi
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
Publikováno v:
Brain Stimul
Brain Stimulation, Vol 15, Iss 1, Pp 23-31 (2022)
Brain Stimulation, Vol 15, Iss 1, Pp 23-31 (2022)
Background: Deep Brain Stimulation (DBS) of the subthalamic nucleus or globus pallidus internus is used to treat the motor symptoms of Parkinson's disease. The former can worsen impulsive and compulsive behaviors after controlling for the reduction o
Autor:
Juho, Joutsa, Khaled, Moussawi, Shan H, Siddiqi, Amir, Abdolahi, William, Drew, Alexander L, Cohen, Thomas J, Ross, Harshawardhan U, Deshpande, Henry Z, Wang, Joel, Bruss, Elliot A, Stein, Nora D, Volkow, Jordan H, Grafman, Edwin, van Wijngaarden, Aaron D, Boes, Michael D, Fox
Publikováno v:
Nature medicine. 28(6)
Drug addiction is a public health crisis for which new treatments are urgently needed. In rare cases, regional brain damage can lead to addiction remission. These cases may be used to identify therapeutic targets for neuromodulation. We analyzed two