Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Khaled Greish"'
Publikováno v:
Molecules, Vol 29, Iss 9, p 2073 (2024)
The concept of nanomedicine has evolved significantly in recent decades, leveraging the unique phenomenon known as the enhanced permeability and retention (EPR) effect. This has facilitated major advancements in targeted drug delivery, imaging, and i
Externí odkaz:
https://doaj.org/article/070fc776d6004b299dc20cdd218b8a13
Publikováno v:
Molecules, Vol 27, Iss 21, p 7259 (2022)
Silver nanoparticles (AgNPs) are widely used commercially due to their antimicrobial effects. Little is known about the effect of AgNPs on neural transmission and pain response. The aim of this study was to assess the anti-nociceptive activity of AgN
Externí odkaz:
https://doaj.org/article/9b799d803b2545978ad340c4082f3a7e
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1771-1775 (2018)
Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO
Externí odkaz:
https://doaj.org/article/2ab48b7af31347d8aceff547ebf1f520
Autor:
Valeria Ciaffaglione, Valeria Consoli, Sebastiano Intagliata, Agostino Marrazzo, Giuseppe Romeo, Valeria Pittalà, Khaled Greish, Luca Vanella, Giuseppe Floresta, Antonio Rescifina, Loredana Salerno, Valeria Sorrenti
Publikováno v:
Molecules, Vol 27, Iss 10, p 3220 (2022)
This paper reports on a novel series of tyrosine kinase inhibitors (TKIs) potentially useful for the treatment of chronic myeloid leukemia (CML). The newly designed and synthesized compounds are structurally related to nilotinib (NIL), a second-gener
Externí odkaz:
https://doaj.org/article/04d5594b9bda4cd4bfd90b74c5595aec
Autor:
Khaled Greish, Abdulla Alawadhi, Ahmed Jaradat, Amer Almarabheh, Marwa AlMadhi, Jaleela Jawad, Basma Alsaffar, Ejlal Alalawi, Adel Alsayyad, Afaf Merza, Batool Alalawi, Donia Qayed, Ahmed Humaidan, Manaf Al Qahtani
Publikováno v:
Vaccines, Vol 10, Iss 4, p 586 (2022)
Background and Objectives: In the current COVID-19 pandemic, children below the age of 12 could manifest COVID-19 symptoms and serve as a reservoir for the virus in the community. The present study was conducted to evaluate the reactogenicity, and im
Externí odkaz:
https://doaj.org/article/f4747fab8f4447f09c428710cff18354
Autor:
Giuseppe Floresta, Antonino Nicolò Fallica, Vincenzo Patamia, Valeria Sorrenti, Khaled Greish, Antonio Rescifina, Valeria Pittalà
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1289 (2021)
HO-1 overexpression has been reported in several cases/types of human malignancies. Unfortunately, poor clinical outcomes are reported in most of these cases, and the inhibition of HO-1 is considered a valuable and proven anticancer approach. To iden
Externí odkaz:
https://doaj.org/article/9f686c33e5db4976b0e05e4c948253c3
Publikováno v:
Molecules, Vol 26, Iss 12, p 3532 (2021)
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of tumors that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. The mainstay of treatment remains chemotherapy, but the therapeutic outcome remains
Externí odkaz:
https://doaj.org/article/55d21d092a0c4020aeecebafe7bdf517
Autor:
Khaled Greish, Safa Taha, Anfal Jasim, Sara Abd Elghany, Ameera Sultan, Ali AlKhateeb, Manal Othman, Fang Jun, Sebastien Taurin, Moiz Bakhiet
Publikováno v:
Clinical and Translational Medicine, Vol 6, Iss 1, Pp 1-10 (2017)
Abstract Background Inflammatory bowel disease (IBD) comprises a group of disorders that manifest through chronic inflammation of the colon and small intestine. Although the exact cause of IBD is still unclear, dysfunctional immunoregulation involvin
Externí odkaz:
https://doaj.org/article/4c77ea9fd113485396e58e1eaaf2095c
Publikováno v:
Pharmaceutics, Vol 12, Iss 11, p 1026 (2020)
The oral delivery of insulin is a convenient and safe physiological route of administration for management of diabetes mellitus. In this study, we developed a poly-(styrene-co-maleic acid) (SMA) micellar system for oral insulin delivery to overcome t
Externí odkaz:
https://doaj.org/article/6d7f0521a3f4421aa3f65444b732fc02
Screening and Molecular Docking of Novel Benzothiazole Derivatives as Potential Antimicrobial Agents
Autor:
Mohamed A. Morsy, Enas M. Ali, Mahmoud Kandeel, Katharigatta N. Venugopala, Anroop B. Nair, Khaled Greish, Mahmoud El-Daly
Publikováno v:
Antibiotics, Vol 9, Iss 5, p 221 (2020)
The burden of antibiotic resistance necessitates a continued search for new antimicrobials. We evaluated the antimicrobial activities of novel benzothiazoles synthesized by our group. Antibacterial activity was evaluated in vitro in Staphylococcus au
Externí odkaz:
https://doaj.org/article/49908171d6874248a3164b89148ee309