Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Khaled Alayed"'
Autor:
Khaled Alayed, Michael Johnson, Howard J. Meyerson, Georgeta Blidaru, Jeremy B Meyerson, Ebenezer S. Osei, June Schlegelmilch
Publikováno v:
American Journal of Clinical Pathology. 153:554-565
Objectives Previously we demonstrated that a decreased percentage of CD177-positive granulocytes detected by flow cytometry (FCM) was associated with myelodysplastic syndrome (MDS). Here we expand on those findings to more rigorously evaluate the uti
Autor:
Khaled, Alayed, Howard J, Meyerson
Publikováno v:
Leukemia research. 112
A decreased percentage of CD177
Autor:
Khaled Alayed, Howard J. Meyerson
Publikováno v:
Leukemia Research. 112:106752
A decreased percentage of CD177pos neutrophils is frequently present in MDS and AML and is a useful flow cytometry (FCM) marker for the identification of MDS. The underlying mechanism leading to the low percentage of CD177pos neutrophils in MDS has n
Autor:
Samir Turakhia, Shashirekha Shetty, Howard J. Meyerson, Khaled Alayed, Amad Awadallah, Karen Schweitzer
Publikováno v:
Journal of Clinical Pathology. 71:906-915
AimDevelop an objective assay to detect c-MYC protein expression using multiparametric flow cytometry (FCM) as an alternative to immunohistochemistry (IHC).Methods57 patient samples and 11 cell line samples were evaluated. Cell suspensions were obtai
Autor:
Jyoti Patel, Khaled Alayed, Danh Phan, Jan Paul V Yap, Chinemerem C. Ojiaku, Carlos E. Bueso-Ramos, Janaya S. Woods, Steven R. Reyes, L. Jeffrey Medeiros, Yen McCord, Sergej Konoplev
Publikováno v:
Archives of Pathology & Laboratory Medicine. 137:1669-1673
Context.—Anti–promyelocytic leukemia (PML) immunofluorescence staining is a known diagnostic tool for rapid diagnosis of acute promyelocytic leukemia (APL). Objective.—We describe our methods using the recently developed, commercially available
Autor:
Carlos E. Bueso-Ramos, Hagop M. Kantarjian, Jorge E. Cortes, Zhuang Zuo, L. Jeffrey Medeiros, Martin Nguyen, Khaled Alayed, Tariq N. Aladily, Zaher Chakhachiro
Publikováno v:
American Journal of Clinical Pathology. 140:370-378
Objectives: To assess CD105 (endoglin) expression in 119 acute myeloid leukemia (AML) and 13 control cases using immunohistochemistry. Methods: CD105 expression was assessed retrospectively by using immunohistochemistry in bone marrow specimens. Resu
Autor:
Keyur P. Patel, Christopher J. Bowman, Khaled Alayed, R. Craig Cason, C. Cameron Yin, Sergio Pina-Oviedo, Joseph D. Khoury, L. Jeffrey Medeiros, Shaoying Li
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 30(5)
Langerhans cell histiocytosis is characterized by a localized or systemic proliferation of Langerhans cells. BRAF mutations have been reported in 40-70% of cases and MAP2K1 mutations have been found in BRAF-negative cases, supporting that Langerhans
Autor:
Khaled Alayed, Shalini Verma, Cheng Cameron Yin, Keyur P. Patel, Shaoying Li, L. Jeffrey Medeiros, John Galbincea, Rajyalakshmi Luthra, Zhuang Zuo, R. Craig Cason
Publikováno v:
Human pathology. 52
Langerhans cell histiocytosis (LCH) is a proliferation of Langerhans cells, often associated with lymphocytes, eosinophils, macrophages, and giant cells. BRAF mutations, usually V600E, have been reported in 40%-70% of cases, and recently, MAP2K1 muta
Autor:
Khaled Alayed, C. Cameron Yin, Roberto N. Miranda, Sanam Loghavi, Shimin Hu, L. Jeffrey Medeiros, Siok Bian Ng, Zhuang Zuo, Guilin Tang, Tariq N. Aladily, Joseph D. Khoury
Publikováno v:
Journal of Hematology & Oncology
Background Plasmablastic lymphoma (PBL) is a rare aggressive neoplasm with lymphoid and plasmacytic differentiation that is commonly associated with immunodeficiency and an unfavorable prognosis. Clinicopathologic features have been largely derived f
Autor:
Sergej Konoplev, Nitin Jain, Mark J. Routbort, Rajesh R. Singh, Abdulaziz Al Shaikh, L. Jeffrey Medeiros, Naveen Pemmaraju, Neelima Reddy, Khaled Alayed, Liping Zhang, Rajyalakshmi Luthra, Keyur P. Patel, Tariq N. Aladily, Joseph D. Khoury
Publikováno v:
American journal of hematology. 88(12)
Distinguishing blastic plasmacytoid dendritic cell neoplasm (BPDCN) from acute myeloid leukemia (AML) is gaining increased importance because of emerging differences in therapeutic approaches, and this distinction can be problematic in bone marrow sp