Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Khaled A. Aly"'
Autor:
Alla Gagarinova, Ali Hosseinnia, Matineh Rahmatbakhsh, Zoe Istace, Sadhna Phanse, Mohamed Taha Moutaoufik, Mara Zilocchi, Qingzhou Zhang, Hiroyuki Aoki, Matthew Jessulat, Sunyoung Kim, Khaled A. Aly, Mohan Babu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The bacterium E. coli has around 300 transcriptional factors, but the functions of many of them, and the interactions between their respective regulatory networks, are unclear. Here, the authors study genetic interactions among all transcription fact
Externí odkaz:
https://doaj.org/article/e26b507a74f145268dd8fb6fa76b67a2
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 2535-2546 (2020)
Neuropsychiatric disorders (NPDs) such as bipolar disorder (BD), schizophrenia (SZ) and mood disorder (MD) are hard to manage due to overlapping symptoms and lack of biomarkers. Risk alleles of BD/SZ/MD are emerging, with evidence suggesting mitochon
Externí odkaz:
https://doaj.org/article/5906bf4df3b44cc9a739c7c8bc02d634
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102030- (2021)
Summary: Mitochondrial (mt) dysfunction is linked to rare diseases (RDs) such as respiratory chain complex (RCC) deficiency, MELAS, and ARSACS. Yet, how altered mt protein networks contribute to these ailments remains understudied. In this perspectiv
Externí odkaz:
https://doaj.org/article/ace72ec956f0447a9b3f72cb48f18ede
Publikováno v:
Microscopy and Microanalysis. 28:1780-1793
The donkey is mainly used as a working animal for riding and pack transport, as well as for dairy and meat production. Eye afflictions are common in donkeys, thus requiring a detailed study. A few studies had focused on the donkey's eye, and most of
Publikováno v:
Seminars in Cancer Biology.
Publikováno v:
The Medical Journal of Cairo University. 88:1933-1942
Background: Breast cancer is one of the most common causes of death among women worldwide. Early detection and diagnosis will be helpful to reduce mortality and improve prognosis. It is urgent to develop efficient detection technology for breast canc
Autor:
Matthew Jessulat, Mohamed Taha Moutaoufik, Khaled A. Aly, Mara Zilocchi, Mohan Babu, Sadhna Phanse
Publikováno v:
Expert Review of Proteomics. 17:119-136
Introduction: Mitochondria (mt) are protein-protein interaction (PPI) hubs in the cell where mt-localized and associated proteins interact in a fashion critical for cell fitness. Altered mtPPIs are linked to neurodegenerative disorders (NDs) and driv
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2535-2546 (2020)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Neuropsychiatric disorders (NPDs) such as bipolar disorder (BD), schizophrenia (SZ) and mood disorder (MD) are hard to manage due to overlapping symptoms and lack of biomarkers. Risk alleles of BD/SZ/MD are emerging, with evid
Neuropsychiatric disorders (NPDs) such as bipolar disorder (BD), schizophrenia (SZ) and mood disorder (MD) are hard to manage due to overlapping symptoms and lack of biomarkers. Risk alleles of BD/SZ/MD are emerging, with evid
Autor:
Maryam Hajikarimlou, Mohsen Hooshyar, Mohamed Taha Moutaoufik, Khaled A Aly, Taha Azad, Sarah Takallou, Sasi Jagadeesan, Sadhna Phanse, Kamaledin B Said, Bahram Samanfar, John C Bell, Frank Dehne, Mohan Babu, Ashkan Golshani
Publikováno v:
NAR genomics and bioinformatics. 4(3)
The coronavirus disease 19 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) prompted the development of diagnostic and therapeutic frameworks for timely containment of this pandemic. Here, we utilized our non-conv
Publikováno v:
Current Opinion in Chemical Biology. 71:102211
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare early-onset neurodegenerative disease caused by mutations in the SACS gene, encoding Sacsin. Initial functional annotation of Sacsin was based on sequence homology, with sub