Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Khaled, Zemoura"'
Autor:
Himanish Ghosh, Luca Auguadri, Sereina Battaglia, Zahra Simone Thirouin, Khaled Zemoura, Simon Messner, Mario A. Acuña, Hendrik Wildner, Gonzalo E. Yévenes, Andrea Dieter, Hiroshi Kawasaki, Michael O. Hottiger, Hanns Ulrich Zeilhofer, Jean-Marc Fritschy, Shiva K. Tyagarajan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Gephyrin is a cytoplasmic scaffolding protein that selectively forms postsynaptic scaffolds at GABAergic and glycinergic synapses. Here the authors characterize regulatory mechanisms determining gephyrin scaffolding and GABAA receptor synaptic transm
Externí odkaz:
https://doaj.org/article/73ddc1c5e39d47848b61414b2085adaa
Publikováno v:
Molecular Neurobiology
Molecular neurobiology, 56 (2)
Molecular neurobiology, 56 (2)
The G protein-coupled GABAB receptors, constituted from GABAB1 and GABAB2 subunits, are important regulators of neuronal excitability by mediating long-lasting inhibition. One factor that determines receptor availability and thereby the strength of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9349cdf56e82990288f671db7d58ea03
https://doi.org/10.1007/s12035-018-1142-5
https://doi.org/10.1007/s12035-018-1142-5
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
GABAB receptors are heterodimeric G protein-coupled receptors, which control neuronal excitability by mediating prolonged inhibition. The magnitude of GABAB receptor-mediated inhibition essentially depends on the amount of receptors in the plasma mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9f25977149bab8ab16147d7d9c3605
https://doi.org/10.1074/jbc.m116.750968
https://doi.org/10.1074/jbc.m116.750968
Publikováno v:
Neuropharmacology
Neuropathic pain is associated with impaired inhibitory control of spinal dorsal horn neurons, which are involved in processing pain signals. The metabotropic GABAB receptor is an important component of the inhibitory system and is highly expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98dd6b41580995e9352fe64e459d3a9
Autor:
Kendrick J. Jones, Hongik Hwang, Bozena Kuzniewska, Franciso X Pena, Magdalena Dziembowska, Ding J Lei, Shannon Nguyen, Christopher Saenz, Khaled Zemoura, Sebastian Templet, Michael C. Lewis, Henny Haensgen, Weifeng Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance De novo protein synthesis is critical for memory formation. We found that protein synthesis during acquisition is transiently required for contextual memory formation. We identified one candidate gene, Nrgn (encoding protein neurogranin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6eab7fbc53f088e266aaa5ccbda9ca
https://doi.org/10.1073/pnas.1716750115
https://doi.org/10.1073/pnas.1716750115
Autor:
Andreas T. Sørensen, Feng-Ju Weng, Karina Alviña, Rodrigo Garófallo Garcia, Taeyun Ku, Khaled Zemoura, Yingxi Lin, Matthew Hung, Stefano Lutzu, Tushar D. Yelhekar, Dario Garcia-Dominguez, Margaret Dushko, Kwanghun Chung, Yuxiang Zhang, Pablo E. Castillo, David C. Rich, Weifeng Xu
Publikováno v:
PMC
Synaptic connections between hippocampal mossy fibers (MFs) and CA3 pyramidal neurons are essential for contextual memory encoding, but the molecular mechanisms regulating MF-CA3 synapses during memory formation and the exact nature of this regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6a89e76aa201049b657bc974b007ab
https://hdl.handle.net/1721.1/128839
https://hdl.handle.net/1721.1/128839
Autor:
Khaled Zemoura, Dietmar Benke
Publikováno v:
The Journal of Biological Chemistry
Regulation of cell surface expression of neurotransmitter receptors is crucial for determining synaptic strength and plasticity, but the underlying mechanisms are not well understood. We previously showed that proteasomal degradation of GABAB recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346e7571811208e0a82013c5cabd8cb9
Autor:
Khaled Zemoura, Marisa Schenkel, Hanns Ulrich Zeilhofer, Dietmar Benke, Gonzalo E. Yévenes, Mario A. Acuña
Publikováno v:
The Journal of biological chemistry
Metabotropic GABAB receptors are crucial for controlling the excitability of neurons by mediating slow inhibition in the CNS. The strength of receptor signaling depends on the number of cell surface receptors, which is thought to be regulated by traf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ade33fa4302e1f4f70a368cdf972d0a
https://doi.org/10.1074/jbc.m113.514745
https://doi.org/10.1074/jbc.m113.514745
Publikováno v:
GABAB Receptor ISBN: 9783319460420
GABAB receptors are heterodimeric G protein-coupled receptors composed of the two seven transmembrane spanning proteins GABAB1 and GABAB2. They are expressed in the vast majority of neurons and primarily regulate neuronal excitability via several dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd293b9d97d255ad00857f25e83cba8
https://doi.org/10.1007/978-3-319-46044-4_4
https://doi.org/10.1007/978-3-319-46044-4_4