Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Khaled, Alsayegh"'
Autor:
Baolei Yuan, Chongwei Bi, Yeteng Tian, Jincheng Wang, Yiqing Jin, Khaled Alsayegh, Muhammad Tehseen, Gang Yi, Xuan Zhou, Yanjiao Shao, Fernanda Vargas Romero, Wolfgang Fischle, Juan Carlos Izpisua Belmonte, Samir Hamdan, Yanyi Huang, Mo Li
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background CRISPR-Cas9 genome editing often induces unintended, large genomic rearrangements, posing potential safety risks. However, there are no methods for mitigating these risks. Results Using long-read individual-molecule sequencing (ID
Externí odkaz:
https://doaj.org/article/d1681b87d8e041b8a7a543e11f0f1746
Autor:
Maryam Alowaysi, Robert Lehmann, Mohammad Al-Shehri, Moayad Baadhaim, Hajar Alzahrani, Doaa Aboalola, Asima Zia, Dalal Malibari, Mustafa Daghestani, Khaled Alghamdi, Ali Haneef, Dunia Jawdat, Fahad Hakami, David Gomez-Cabrero, Jesper Tegner, Khaled Alsayegh
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Human iPSCs' derivation and use in clinical studies are transforming medicine. Yet, there is a high cost and long waiting time associated with autologous iPS-based cellular therapy, and the genetic engineering of hypo-immunogenic
Externí odkaz:
https://doaj.org/article/6dd0a040a789495da7871c502a54028c
Autor:
Mohammed N. Baeshen, Roba Attar, Thamer A. Bouback, Abdulaziz O. Albeshri, Naseebh N. Baeshen, Alaa Karkashan, Basma Abbas, Abdullah A. Aljaddawi, Yaaser Q. Almulaiky, Sara H. Mahmoud, Noura M. Abo Shama, Mohamed A. Ali, Moayad Baadhaim, Samer Zakri, Khaled Alsayegh, Arif Mohammed, Nabih A. Baeshen
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 36, Iss 1, Pp 68-74 (2022)
AbstractThe emergence of superbugs and resistant pathogens poses a challenge in scientific and medical research as they threaten public health worldwide. Many herbal natural products currently used in therapies have been suggested to exert antimicrob
Externí odkaz:
https://doaj.org/article/8d09751fb4ed476bb47cd05e8e27ee59
Autor:
Maryam Alowaysi, Mohammad Al-Shehri, Moayad Baadhaim, Hajar AlZahrani, Doaa Aboalola, Mustafa Daghestani, Heba Hashem, Rawan Aljahdali, Rayan Salem, Adel Alharbi, Mohammed Muharraq, Khaled Alghamdi, Fawaz Alsobiy, Asima Zia, Robert Lehmann, Jesper Tegner, Khaled Alsayegh
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103158- (2023)
Myoglobin (MB) is a cytoplasmic hemoprotein that is predominantly expressed in the heart and oxidative myofibers of skeletal muscle. It has been demonstrated that MB binds to oxygen and promotes its diffusion for energy production in the mitochondria
Externí odkaz:
https://doaj.org/article/baec57c5daa944d2843c788119c37229
Autor:
Doaa Aboalola, Heba Badraiq, Rawiah Alsiary, Samer Zakri, Neda Aboulola, Loay Haneef, Dalal Malibari, Moayad Baadhaim, Khaled Alsayegh
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
In recent years, the industry of unproven stem cell-based therapies has been on the rise around the globe, putting patients at great risk of potential harm. In this cross-sectional study, we aimed to assess the level of knowledge and awareness of the
Externí odkaz:
https://doaj.org/article/474aeea4e5e24bfa9729b6d4870e3d0f
Autor:
Mohammad Al-Shehri, Moayad Baadhaim, Shereen Jamalalddin, Doaa Aboalola, Mustafa Daghestani, Hajar AlZahrani, Dalal Malibari, Mohammad Mubaraki, Kholoud Aldubayan, Mohammed AlBalwi, Khaled Alsayegh
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102548- (2021)
In this study we isolated and enriched erythroid progenitor cells (EPCs) from a 10 ml peripheral blood sample from a 37-year old healthy Saudi donor. After expansion, these EPCs were reprogrammed using episomal plasmids to generate an induced pluripo
Externí odkaz:
https://doaj.org/article/18b583e556e6416f8a707cba0b5100d9
Autor:
Baolei Yuan, Chongwei Bi, Jinchen Wang, Yiqing Jin, Khaled Alsayegh, Muhammad Tehseen, Gang Yi, Samir Hamdan, Yanyi Huang, Mo Li
CRISPR-Cas9, an efficient genome editing tool, has been widely used in research and holds great promise in the clinic. However, large unintended rearrangements of the genome occur frequently after CRISPR-Cas9 editing and their potential risk cannot b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e329abbb1e42eba4b9675c849be1306
https://doi.org/10.1101/2022.11.16.516713
https://doi.org/10.1101/2022.11.16.516713
Autor:
Khaled Alsayegh, Mo Li, Anieka J. Parry, Shannon G. Klein, Carlos M. Duarte, Juan Carlos Izpisua Belmonte, Alexandra Steckbauer, Samhan M. Alsolami, Gerardo Ramos Mandujano, Silvia Arossa
Publikováno v:
Nature Biomedical Engineering. 5:787-792
We thank members of the Li laboratory for helpful discussions, and J. Xu and M. K. Y. Sicat for administrative support. We also thank members of the Izpisua Belmonte laboratory for their critical feedback on early versions of the manuscript. This wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d762bf320e96a900cd44f061fe3d2d45
https://doi.org/10.1038/s41551-021-00775-0
https://doi.org/10.1038/s41551-021-00775-0
Autor:
Shannon G, Klein, Samhan M, Alsolami, Alexandra, Steckbauer, Silvia, Arossa, Anieka J, Parry, Gerardo, Ramos Mandujano, Khaled, Alsayegh, Juan Carlos, Izpisua Belmonte, Mo, Li, Carlos M, Duarte
Publikováno v:
Nature biomedical engineering. 5(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7f8432cee3d2e7c23c9aca201cfdb6c
https://pubmed.ncbi.nlm.nih.gov/34389822
https://pubmed.ncbi.nlm.nih.gov/34389822
Autor:
Dalal Malibari, Khaled Alsayegh, Hajar Alzahrani, Kholoud Aldubayan, Mohammad Mubaraki, Moayad Baadhaim, Shereen Jamalalddin, Mustafa Daghestani, Mohammed AlBalwi, Mohammad Al-Shehri, Doaa Aboalola
Publikováno v:
Stem Cell Research, Vol 56, Iss, Pp 102548-(2021)
In this study we isolated and enriched erythroid progenitor cells (EPCs) from a 10 ml peripheral blood sample from a 37-year old healthy Saudi donor. After expansion, these EPCs were reprogrammed using episomal plasmids to generate an induced pluripo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99631cbfc70c3cd877c0101bc5d52d0f
https://pubmed.ncbi.nlm.nih.gov/34592601
https://pubmed.ncbi.nlm.nih.gov/34592601