Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Khaled, Alganem"'
Autor:
Abdul-rizaq Hamoud, Khaled Alganem, Sean Hanna, Michael Morran, Nicholas Henkel, Ali S. Imami, William Ryan, Smita Sahay, Priyanka Pulvender, Austin Kunch, Taylen O. Arvay, Jarek Meller, Rammohan Shukla, Sinead M. O’Donovan, Robert McCullumsmith
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Protein kinases are critical components of a myriad biological processes and strongly associated with various diseases. While kinase research has been a point of focus in biomedical research for several decades, a large portion of the kinome
Externí odkaz:
https://doaj.org/article/0fe77c7a32824f5db32b05dec26eb13a
Autor:
Jennifer Nguyen, Melissa A. Curtis, Ali S. Imami, William G. Ryan, Khaled Alganem, Kari L. Neifer, Nilanjana Saferin, Charlotte N. Nawor, Brian P. Kistler, Gary W. Miller, Rammohan Shukla, Robert E. McCullumsmith
Publikováno v:
Translation, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/19421693822744e0944eb21064314f3a
Autor:
Lauren Wegman-Points, Khaled Alganem, Ali Sajid Imami, Victoria Mathis, Justin Fortune Creeden, Robert McCullumsmith, Li-Lian Yuan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Protein kinases and their substrates form signaling networks partitioned across subcellular compartments to facilitate critical biological processes. While the subcellular roles of many individual kinases have been elucidated, a comprehensiv
Externí odkaz:
https://doaj.org/article/70e562c31ee1428fa5635716503723f4
Autor:
Ketan K. Marballi, Khaled Alganem, Samuel J. Brunwasser, Arhem Barkatullah, Kimberly T. Meyers, Janet M. Campbell, Annika B. Ozols, Robert E. Mccullumsmith, Amelia L. Gallitano
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Bioinformatics and network studies have identified the immediate early gene transcription factor early growth response 3 (EGR3) as a master regulator of genes differentially expressed in the brains of patients with neuropsychiatric illnesses
Externí odkaz:
https://doaj.org/article/81fb50e775ac47e18e756a66b4665804
Autor:
Boren Lin, Khaled Alganem, Sinead M. O’Donovan, Zhen Jin, FarzanehSadat Naghavi, Olivia A. Miller, Tyler C. Ortyl, Ye Chun Ruan, Robert E. McCullumsmith, Jianyang Du
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Reconsolidation has been considered a process in which a consolidated memory is turned into a labile stage. Within the reconsolidation window, the labile memory can be either erased or strengthened. Manipulating acid-sensing ion channels (AS
Externí odkaz:
https://doaj.org/article/f2eef7bfc2ca41ef902828beeefe4684
Autor:
Erica A K DePasquale, Khaled Alganem, Eduard Bentea, Nawshaba Nawreen, Jennifer L McGuire, Tushar Tomar, Faris Naji, Riet Hilhorst, Jaroslaw Meller, Robert E McCullumsmith
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260440 (2021)
Phosphorylation by serine-threonine and tyrosine kinases is critical for determining protein function. Array-based platforms for measuring reporter peptide signal levels allow for differential phosphorylation analysis between conditions for distinct
Externí odkaz:
https://doaj.org/article/fbeae036ba4e4805806f7b1078411edb
Publikováno v:
Schizophr Res
Altered expression and localization of the glutamate transporter EAAT2 is found in schizophrenia and other neuropsychiatric (major depression, MDD) and neurological disorders (amyotrophic lateral sclerosis, ALS). However, the EAAT2 interactome, the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163f801d9923920bca70dd5e48feca72
https://doi.org/10.1016/j.schres.2020.03.018
https://doi.org/10.1016/j.schres.2020.03.018
Autor:
Robin C. Su, Joshua D. Breidenbach, Khaled Alganem, Fatimah K. Khalaf, Benjamin W. French, Prabhatchandra Dube, Deepak Malhotra, Robert McCullumsmith, John B. Presloid, R. Mark Wooten, David J. Kennedy, Steven T. Haller
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9939 (2021)
We were the first to previously report that microcystin-LR (MC-LR) has limited effects within the colons of healthy mice but has toxic effects within colons of mice with pre-existing inflammatory bowel disease. In the current investigation, we aimed
Externí odkaz:
https://doaj.org/article/3155eb4fe2a846e3a19e8f384b6dd915
Autor:
Justin F. Creeden, Zachary A. Kipp, Mei Xu, Robert M. Flight, Hunter N. B. Moseley, Genesee J. Martinez, Wang‐Hsin Lee, Khaled Alganem, Ali S. Imami, Megan R. McMullen, Sanjoy Roychowdhury, Atta M. Nawabi, Jennifer A. Hipp, Samir Softic, Steven A. Weinman, Robert McCullumsmith, Laura E. Nagy, Terry D. Hinds
Publikováno v:
Hepatology. 76:1376-1388
Resolution of pathways that converge to induce deleterious effects in hepatic diseases, such as in the later stages, have potential antifibrotic effects that may improve outcomes. We aimed to explore whether humans and rodents display similar fibroti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64ac9e52f717413e99715100e1a652f
https://doi.org/10.1002/hep.32467
https://doi.org/10.1002/hep.32467
Autor:
Justin F. Creeden, Khaled Alganem, Ali S. Imami, F. Charles Brunicardi, Shi-He Liu, Rammohan Shukla, Tushar Tomar, Faris Naji, Robert E. McCullumsmith
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8679 (2020)
Pancreatic cancer remains one of the most difficult malignancies to treat. Minimal improvements in patient outcomes and persistently abysmal patient survival rates underscore the great need for new treatment strategies. Currently, there is intense in
Externí odkaz:
https://doaj.org/article/1913e2c584794d5299f985afd4a8da6e